Optofluidic liquid sensing on electromicrofluidic devices
Source abstract
Abstract
Abstract Electromicrofluidic (EMF) devices are used to handle and move tiny amounts of liquids by electrical actuation, including electrowetting-on-dielectric (EWOD) and dielectrophoresis (DEP). Monitoring the liquid characteristics in one of these devices requires suitable sensing transducers incorporated within the microfluidic structure. In the present work, we describe the incorporation of an optofluidic photonic transducer in an EMF device to monitor the refractive index of a liquid during its manipulation. The incorporated transducer consists of a responsive porous Bragg Microcavity (BM) deposited via physical vapor oblique angle deposition. Besides reporting the manufacturing procedure of the sensing-EMF device combining liquid handling and monitoring, the performance of the BM is verified by infiltrating several liquids dripped on its surface and comparing the responses with those of liquid droplets electrically moved from the delivery part of the chip to the BM location. This study proved that modified EMF devices can incorporate photonic structures to analyze very low liquid volumes (∼0.2 μL) during its handling.
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Research context
OpenAlex topics: Electrowetting and Microfluidic Technologies · Photonic and Optical Devices · Photonic Crystals and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (39)
Show source-provided references
1. Developing optofluidic technology through the fusion of microfluidics and optics10.1038/nature05060 ↗
2. Nanoholes as nanochannels: flow-through plasmonic sensing10.1021/ac900221y ↗
3. Spectral sensitivity of two-dimensional nanohole array surface plasmon polariton resonance sensor10.1063/1.2789181 ↗
4. Metallic nanohole arrays on fluoropolymer substrates as small label-free real-time bioprobes10.1021/nl801043t ↗
5. Plasmonic nanoholes in a multichannel microarray format for parallel kinetic assays and differential sensing10.1021/ac802276x ↗
6. Integrated nanoplasmonic-nanofluidic biosensors with targeted delivery of analytes10.1063/1.3290633 ↗
7. Reversible and irreversible control of optical properties of porous silicon superlattices by thermal oxidation, vapor adsorption, and liquid penetration10.1116/1.581438 ↗
8. Inverse silica opal photonic crystals for optical sensing applications10.1364/OE.15.012979 ↗
9. Silicon photonic crystal nanostructures for refractive index sensing10.1063/1.3009203 ↗
10. Photonic crystals for fluid sensing in the subterahertz range10.1063/1.2369537 ↗
11. Sub-micrometric reflectometry for localized label-free biosensing10.1364/OE.23.012544 ↗
12. Photonic crystal fiber long-period gratings for biochemical sensing10.1364/OE.14.008224 ↗
13. Optofluidic microsystems for chemical and biological analysis10.1038/nphoton.2011.206 ↗
14. Electrowetting: from basics to applications10.1088/0953-8984/17/28/R01 ↗
15. Multiphase optofluidics on an electro-microfluidic platform powered by electrowetting and dielectrophoresis10.1039/C4LC00317A ↗
16. General digital microfluidic platform manipulating dielectric and conductive droplets by dielectrophoresis and electrowetting10.1039/b816535a ↗
17. Encapsulated droplets with metered and removable oil shells by electrowetting and dielectrophoresis10.1039/c1lc20142e ↗
18. Constructing 3D heterogeneous hydrogels from electrically manipulated prepolymer droplets and crosslinked microgels10.1126/sciadv.1600964 ↗
19. Atmospheric-pressure microplasma in dielectrophoresis-driven bubbles for optical emission spectroscopy10.1039/c2lc40499k ↗
20. In situ characterization of microdroplet interfacial properties in digital microfluidic systems10.1039/b925665b ↗
21. SPR microscopy and its applications to high-throughput analyses of biomolecular binding events and their kinetics10.1016/j.biomaterials.2007.01.047 ↗
22. Miniaturization of fiber optic surface plasmon resonance sensor10.1016/S0925-4005(98)00205-6 ↗
23. Surface plasmon resonance sensors for detection of chemical and biological species10.1021/cr068107d ↗
24. Surface plasmon resonance biosensor based on smart phone platforms10.1038/srep12864 ↗
25. Review of plasmonic fiber optic biochemical sensors: improving the limit of detection10.1007/s00216-014-8411-6 ↗
26. Cytometry on a chip: Cellular phenotypic and functional analysis using grating-coupled surface plasmon resonance10.1016/j.bios.2005.12.021 ↗
27. Surface plasmon resonance imaging of biomolecular interactions on a grating-based sensor array10.1021/ac0519209 ↗
28. Mie theory for light scattering by a spherical particle in an absorbing medium10.1364/AO.40.001354 ↗
29. Calculated absorption and scattering properties of gold nanoparticles of different size, shape, and composition: applications in biological imaging and biomedicine10.1021/jp057170o ↗
30. Microfluidic surface plasmon resonance sensors: from principles to point-of-care applications10.3390/s16081175 ↗
31. Two-dimensional droplet-based surface plasmon resonance imaging using electrowetting-on-dielectric microfluidics10.1039/B814697G ↗
32. Integrating optical waveguides in electrowetting-on-dielectric digital microfluidic chips10.1016/j.snb.2013.01.078 ↗
33. Chip scale integration of optical microresonator sensors with digital microfludics systems10.1109/LEOS.2008.4688588 ↗
34. Chip scale optical microresonator sensors integrated with embedded thin film photodetectors on electrowetting digital microfluidics platforms10.1109/JSEN.2011.2179027 ↗
35. Silicon photonic sensors incorporated in a digital microfluidic system10.1007/s00216-012-6319-6 ↗
36. Liquids analysis with optofluidic bragg microcavities10.1021/am401685r ↗
37. Optofluidic modulation of self-associated nanostructural units forming planar bragg microcavities10.1021/acsnano.5b06625 ↗
38. Robust polarization active nanostructured 1D Bragg Microcavities as optofluidic label-free refractive index sensor10.1016/j.snb.2017.10.060 ↗
39. Transparent and conducting ITO films: new developments and applications10.1016/S0040-6090(02)00163-3 ↗