Studies on the antifungal activity of biotemplated gold nanoparticles over Candida albicans

Abstract Green synthesis and applications of gold nanoparticles are more fascinating research area due to their unique optical properties and high X-ray attenuation power. In this study, we have synthesized gold nanoparticles of uniform size (5 nm) with spherical shape. UV–vis spectroscopy, Transmission Electron Microscopy and Atomic Force Microscopy were employed to characterize the synthesized gold nanoparticles. The biomedical applications of the synthesized gold nanoparticles were carried out against most prevalent human fungal pathogen, Candida albicans. Broth micro dilution assay was used to determine minimum inhibitory concentration (MIC). We observed that 0. 5 mM concentration was effective in inhibiting the growth of fungal cells which was later confirmed by spot assay.