journal article·2022-03

Eco-friendly copper nanomaterials-based dual-mode optical nanosensors for ultrasensitive trace determination of amoxicillin antibiotics residue in tap water samples

Nguyen Tuan Anh, Ngo Xuan Dinh, Hoang Van Tuan, Mai Quan Doan, Nguyen Ha Anh, Nguyen Tien Khi, Vu Thi Trang, Doan Quang Tri, Anh-Tuan Le

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Abstract

Abstract In this study, we have developed, for the first time, a colorimetric and surface-enhanced Raman scattering (SERS) dual-mode sensing platform for sensitive amoxicillin (AMX) detection by employing electrochemically-synthesized copper nanoparticles (CuNPs) and copper-graphene oxide (Cu-GO) nanocomposites with low cost and high purity. The obtained results revealed that Cu-GO-based colorimetric nanosensor exhibited high sensitivity with AMX antibiotics in a linear working range from 5 to 50 µM with a limit of detection (LOD) of 1.71 µM, which was 1.3 times lower than that of CuNPs-based colorimetric nanosensor (2.17 µM). More interestingly, Cu-GO-based SERS nanosensor has a linear range from 0.01 to 1000 µM and a LOD value ∼x223C 0.0012 µM, which was ∼x223C 13 times lower than CuNPs-based SERS sensor (0.0152 µM). Our developed dual-mode optical nanosensors also exhibited good practical applicability for AMX detection in real tap-water samples with high accuracy as recovery rates were calculated about 95% and RSDs were less than 5%.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Gold and Silver Nanoparticles Synthesis and Applications · Biosensors and Analytical Detection

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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