journal article·2025-12Open access

Enhanced electrochemical ascorbic acid sensing via synergistic TiO2 nanoparticle and molecularly imprinted polymer modified carbon paste electrodes

Ria Sri Rahayu, Roro Arwinda Filzahimka, Annisa Anggitami, Muhammad Arya Nugraha, Muhammad Yudhistira Azis

Materials Letters· Volume 401

Abstract

An electrochemical sensor for ascorbic acid (AA) was developed using a carbon paste electrode (CPE) modified with titanium dioxide (TiO 2 ) nanoparticles and molecularly imprinted polymer (MIP) based on methyl red. Surface deposition of TiO 2 , followed by MIP modification, increased the oxidation peak current by 30.8 %. The sensor exhibited four linear response ranges (1–10 μM, 10–100 μM, 100–1000 μM, and 1–10 mM), with a detection limit of 0.7 μM. It also demonstrated excellent repeatability (RSD = 2.68 %) and reproducibility (RSD = 2.25 %). The structural and compositional integration of TiO 2 and MIP was confirmed through scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), and Brunauer-Emmett-Teller (BET) analysis. These results support its use in clinical and food safety AA detection.
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Research context

OpenAlex topics: Electrochemical sensors and biosensors · Electrochemical Analysis and Applications · Analytical Chemistry and Sensors

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