Semi-confined synthesis of hollow mesoporous Carbon@Silica nanoparticles with amphipathic dual-shell

Abstract Amphiphilic dual-shell mesoporous carbon@silica nanoparticles were successfully synthesized via a semi-confined pyrolysis strategy. The external silica shell with radial orient mesochannels provided a characteristic semi-confined nanospace as well as a hard protection layer to construct the dual-shell structures. Intriguingly, the composite polymers could display a library of newfangled structures from flower-shaped to semi-yolk shell spheres and cauliflower-like morphology by modulating the amount of NH3·H2O, for it can not only mediate the construction of polymer-silica surface but control the assembly process. This novel dual-shell hollow nanoparticles manifested a perfect dispersion in water and a remarkable performance as a drug carrier to improve the release rate of Naproxen.