DataVXBiointerphasesPaper
journal article·2016-06-01

Functionalization of poly(ε-caprolactone) surface with lactose-modified chitosan via alkaline hydrolysis: ToF-SIMS characterization

Luca Tortora, Sofia Concolato, Marco Urbini, Sara Maria Giannitelli, Francesco Basoli, Alberto Rainer, Marcella Trombetta, Monica Orsini, Pamela Mozetic

Biointerphases· Volume 11· Issue 2
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Source abstract

Abstract

Functionalization of poly(ε-caprolactone) (PCL) was performed via hydrolysis and subsequent grafting of lactose-modified chitosan (chitlac) at two different degrees of derivatization (9% and 64%). Time of flight secondary ion mass spectrometry (ToF-SIMS) and multivariate analysis (principal component analysis) were successfully applied to the characterization of PCL surface chemistry, evidencing changes in the biopolymer surface following base-catalyzed hydrolysis treatment. ToF-SIMS analysis also confirmed positive EDC/NHS-catalyzed (EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; NHS: N-hydroxysuccinimide) immobilization of chitlac onto activated PCL surface, with formation of amide bonds between PCL surface carboxyl groups and amine residues of chitlac. Yield of grafting reaction was also shown to be dependent upon the lactosilation degree of chitlac.
Source: crossref · Quality: baseline

Research context

Catalysis & surfaces

OpenAlex topics: Nanocomposite Films for Food Packaging · biodegradable polymer synthesis and properties · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Roma Tre University Department of Mathematics and Physics and INFN, Surface Analysis Laboratory, , Via della Vasca Navale 84, 00146 Rome, Italy

Roma Tre University Department of Mathematics and Physics and INFN, Surface Analysis Laboratory, , Via della Vasca Navale 84, 00146 Rome, Italy and Department of Engineering, , Via Vito Volterra 62, 00146 Rome, Italy

Roma Tre University Department of Mathematics and Physics and INFN, Surface Analysis Laboratory, , Via della Vasca Navale 84, 00146 Rome, Italy and Department of Industrial Engineering, Via del Politecnico 1, 00133 Roma, Italy

University of Rome “Tor Vergata,” Department of Mathematics and Physics and INFN, Surface Analysis Laboratory, , Via della Vasca Navale 84, 00146 Rome, Italy and Department of Industrial Engineering, Via del Politecnico 1, 00133 Roma, Italy

“Università Campus Bio-Medico di Roma,” Tissue Engineering Unit, via Álvaro del Portillo 21, 00128 Roma, Italy

Roma Tre University Department of Engineering, , Via Vito Volterra 62, 00146 Roma, Italy

Funding

Fondazione Roma

References (34)

Show source-provided references
1. Prog. Polym. Sci. · 2010 · 35 · 121710.1016/j.progpolymsci.2010.04.002 ↗
2. Polymer · 2015 · 64 · 11210.1016/j.polymer.2015.03.025 ↗
3. Biointerphases · 2014 · 9 · 02901110.1116/1.4870781 ↗
4. Biointerphases · 2009 · 4 · FA310.1116/1.3089252 ↗
5. Acta Biomater. · 2013 · 9 · 769910.1016/j.actbio.2013.05.003 ↗
6. Asia-Pac. J. Chem. Eng. · 2014 · 9 · 40110.1002/apj.1809 ↗
7. Plasma Processes Polym. · 2011 · 8 · 25610.1002/ppap.201000009 ↗
8. Macromol. Symp. · 1996 · 101 · 44310.1002/masy.19961010150 ↗
9. Adv. Polym. Sci. · 2004 · 169 · 23110.1007/b13524 ↗
10. Mater. Sci. Eng., C · 2015 · 57 · 33810.1016/j.msec.2015.07.015 ↗
11. Biomacromolecules · 2009 · 10 · 235110.1021/bm900186s ↗
12. Biomaterials · 2014 · 35 · 902310.1016/j.biomaterials.2014.07.015 ↗
13. Prog. Polym. Sci. · 2011 · 36 · 98110.1016/j.progpolymsci.2011.02.001 ↗
14. Nature · 1983 · 302 · 81210.1038/302812a0 ↗
15. J. Phys. Chem. · 2013 · 117 · 1357810.1021/jp4067263 ↗
16. Biomacromolecules · 2012 · 13 · 156410.1021/bm3002683 ↗
17. Biomaterials · 2003 · 24 · 363510.1016/S0142-9612(03)00159-5 ↗
18. Surf. Interface Anal. · 2009 · 41 · 64510.1002/sia.3056 ↗
19. J. Mater. Sci.: Mater. Med. · 2012 · 23 · 29310.1007/s10856-011-4527-9 ↗
20. Anal. Chem. · 2000 · 72 · 562510.1021/ac000450+ ↗
21. J. Biomater. Sci., Polym. Ed. · 2016 · 27 · 6910.1080/09205063.2015.1108637 ↗
22. Appl. Surf. Sci. · 2015 · 327 · 29610.1016/j.apsusc.2014.11.185 ↗
23. Biomaterials · 2005 · 26 · 497510.1016/j.biomaterials.2005.01.044 ↗
24. Biomaterials · 2005 · 26 · 98710.1016/j.biomaterials.2004.04.015 ↗
25. 2012 · 473
26. Polym. Int. · 2006 · 55 · 133610.1002/pi.2090 ↗
27. Polym. Prepr. · 2011 · 52 · 325
28. J. Biomater. Sci., Polym. Ed. · 2015 · 26 · 51510.1080/09205063.2015.1030991 ↗
29. Appl. Surf. Sci. · 2003 · 203–204 · 85510.1016/S0169-4332(02)00822-X ↗
30. Anal. Chem. · 2006 · 78 · 182710.1021/ac051624w ↗
31. ACS Nano · 2011 · 5 · 154910.1021/nn103577g ↗
32. See supplementary material at http://dx.doi.org/10.1116/1.4942498 for positive and negative ToF-SIMS spectra of standard and treated samples: PCLctrl, PCLActrl and PCLAhydro. Positive ion peaks of PCL used for PCA are also reported.
33. J. Mater. Chem. · 2010 · 20 · 48310.1039/B911854C ↗
34. 1998 · 511