Microscopic and nanoscopic protein imaging by SIMS and helium ion microscopy
Source abstract
Abstract
Single protein imaging and understanding their interactions are of paramount importance to understand the life phenomena. Recently reported multiplex protein SIMS imaging methodology using metal-oxide nanoparticle conjugated antibodies can be extended to a single protein imaging methodology using He ion microscopy (HIM). It is proposed here that single protein can be imaged in the microscale and the nanoscale by the complementary use of SIMS and HIM.
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Research context
OpenAlex topics: Ion-surface interactions and analysis · Nanopore and Nanochannel Transport Studies · Advanced Electron Microscopy Techniques and Applications
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Affiliations
Department of New Biology, DGIST 1 , 333, Techno Jungang-daero, Dalsung, Daegu 711-873, South Korea
School of Undergraduate Studies, DGIST 2 , 333, Techno Jungang-daero, Dalsung, Daegu 711-873, South Korea
Funding
DGIST R&D Program of the Ministry of Science, ICT & Future Planning · National Research Foundation of Korea
References (12)
Show source-provided references
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