journal article·2015-06-01Open access

Composite nature of fresh skin revealed during compression

Benjamin J. Butler, Rachael L. Boddy, Chiara Bo, Hari Arora, Alun Williams, William G. Proud, Katherine A. Brown

Abstract

Biological systems are subjected to moderate-to-high strain rates in blast-type traumatic injuries. An improved understanding of the responses of cells and tissues to extreme mechanical stresses could improve mitigation and post-injury treatment strategies. A key aim of this research is to create biologically meaningful injury models of soft tissues. Here the authors examine the material and cellular properties of freshly harvested porcine skin in compression. The data presented suggest that fresh skin differentially responds low to moderate strain rates as a composite rather than that of a homogeneous polymer. The implications of this work are discussed in terms of creating improved analytical models to describe the material properties of fresh skin.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Elasticity and Material Modeling · Structural Response to Dynamic Loads · Automotive and Human Injury Biomechanics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Graduate Student, The Royal British Legion Centre for Blast Injury Studies, Imperial College London, London, UK

Surfaces, Microstructure and Fracture Group, Cavendish Laboratory, University of Cambridge, Cambridge, UK

Graduate Student, Surfaces, Microstructure and Fracture Group, Cavendish Laboratory, University of Cambridge, Cambridge, UK

Postdoctoral Researcher, The Royal British Legion Centre for Blast Injury Studies, Imperial College London, London, UK

Institute of Shock Physics, Imperial College London, London, UK

Research Fellow, The Royal British Legion Centre for Blast Injury Studies, Imperial College London, London, UK

Department of Bioengineering, Imperial College London, London, UK

Professor, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK

Reader, The Royal British Legion Centre for Blast Injury Studies, Imperial College London, London, UK

Senior Research Fellow, The Royal British Legion Centre for Blast Injury Studies, Imperial College London, London, UK

Department of Chemistry, University of Texas at Austin, Austin, TX, USA

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