journal article·2022-05

Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: An efficient and biocompatible wound-dressing material

Mohammed Bello, Faizuan Abdullah, Abdull Rahim Mohd Yusoff, Wan Mohd Asyraf Wan Mahmood, Tan Yong Chee, Nik Ahmad Nizam Nik Malek, Khairunnadwa Binti Jemon, Palanivel Sathishkumar

Materials Letters· Volume 315
Publisher page

Abstract

The present study aims to produce a natural drug-incorporated nano-based wound-dressing material with high biocompatibility and enhanced antibacterial efficacy for promoting rapid wound healing. Electrospun curcumin-loaded poly(ɛ-caprolactone) (PCL/Cur) membrane is successfully fabricated and characterized using standard techniques. The fabricated PCL/Cur membrane showed a higher antibacterial effect against the bacterial strains, Staphylococcus aureus and Escherichia coli; whereas, a very less cytotoxic effect was observed on the mouse fibroblast (L929) cells. This study concludes that PCL/Cur membrane could be a simple, biocompatible, and efficient material for wound-dressing applications.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Wound Healing and Treatments · Silk-based biomaterials and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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