journal article·2021-02

Camptothecin-loaded holmium ferrite nanocarrier. Expanded activity on breast cancer cells

Kiruthiga Kaliyamoorthi, Sivaraj Ramasamy, Archana Sumohan Pillai, Aleyamma Alexander, Anitha Arivarasu, Israel V.M.V. Enoch

Materials Letters· Volume 285
Publisher page

Abstract

Abstract To achieve magnetic field-assisted drug delivery, magnetic nanocarriers have to be designed. In this paper, we report the synthesis of holmium ferrite nanoparticles. The nanoparticles are coated with cyclodextrin-polyethylene glycol conjugate. The nanoparticles are characterized using X-ray diffraction, EDX, and XPS. The nanoparticles are of the size range suitable for effective drug delivery. The holmium ferrite nanoparticles are superparamagnetic. An anticancer drug, camptothecin, is loaded on the nanocarrier with an adsorption percentage of 92%. The efficacy of the anticancer drug is enhanced on employing the magnetic nanocarrier.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Nanoparticle-Based Drug Delivery · Graphene and Nanomaterials Applications · Nanomaterials for catalytic reactions

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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