Biomimetic apatite coating on magnetite particles

Apatite-coated magnetite particles have been prepared using a novel biomimetic method. This method consisted of immersing magnetite particles in simulated body fluids (SBF, 1.5 SBF) along with disk-shaped sintered wollastonite. Different routes were followed: 7 days of immersion in SBF or 1.5 SBF and 7 or 28 days using a re-immersion method. The magnetic properties were evaluated both before and after the biomimetic process. A bone-like apatite layer was formed on all the samples tested and not a significant change was observed on their original magnetic behavior. These bioactive and superparamagnetic particles may be potential materials for bone cancer treatment.