Utilization of Ocimum basilicum extracts for zinc oxide nanoparticles synthesis and their antibacterial activity after a novel combination with phage
Source abstract
Abstract
Abstract The current study illustrates the synergetic effect of both environment-friendly green synthesized zinc oxide nanoparticles (ZnO-NPs) of Ocimum basilicum extract using the bio-reduction process and bacteriophages (phage) to control pathogenic bacteria. Ocimum basilicum has various phytochemical compounds that were responsible for the formation of ZnO-NPs. In addition, the phage ZCSE6, as a biological material, has a bacteriolytic activity against pathogenic bacteria. The spectrum of UV-Vis indicated a corresponding ZnO-NPs peak at 370 nm. Transmission electron micrographs (TEM) showed irregular particles in shape with 10-25 nm in size. Furthermore, the ZnO-NPs displayed biofilm deformation that can be formed by Staphylococcus sciuri (S. sciuri). Moreover, it has a synergic antibacterial activity against Salmonella enterica (S. enterica) when combined with phage ZCSE6. This study reveals the antibacterial effect of using metallic and biological materials and their possible applications in the medical field.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bacteriophages and microbial interactions · Nanoparticles: synthesis and applications · Aquaculture disease management and microbiota
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (12)
Show source-provided references
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