Fabrication of calcium phosphate fibres through electrospinning and sintering of hydroxyapatite nanoparticles
Source abstract
Abstract
Calcium phosphate (CaP) materials such as synthetic hydroxyapatite (HA, Ca10(PO4)6·(OH)2) and β-tricalcium phosphate (β-TCP, Ca3(PO4)2) are well-known for their potential in bone tissue engineering and drug delivery applications. Processing such materials into submicrofibres might contribute to improve their biocompatibility. This paper presents a new method for creating CaP submicrofibres through the electrospinning route. A thermal treatment at sintering temperature (1100 °C) was applied to electrospun polymer fibres filled with hydroxyapatite nanoparticles to cause aggregation of the nanoparticles and vaporise the polymer matrix. The images taken by electron microscopy revealed that the treated samples maintained their submicrofibrous morphology. Moreover, Fourier transform infrared spectroscopy, X-ray diffraction and X-ray photoelectron spectroscopy analysis confirmed that the resulting fibres are made of hydroxypatite and tricalcium phosphates.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Electrospun Nanofibers in Biomedical Applications · Dental materials and restorations
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (27)
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