Extraction, characterization, and NO release potential of keratin from human hair
Source abstract
Abstract
Abstract Keratin-based biomaterials have emerged as potential candidates for various biomedical and biotechnological applications due to their intrinsic biocompatibility, biodegradability, mechanical durability, and natural abundance. The objective of our study is to explore the feasibility and potential applications of keratin for promoting nitric oxide (NO) release. Herein, keratin was first extracted from human hair and then modified with iodoacetic acid to afford S-carboxymethyl keratin. The amino acid residues, isoelectric point, and molecular weight of keratin were quantified with amino acid analyzer, zeta potential measurement, and SDS-PAGE method. Interestingly, human hair keratin was proved to be capable of promoting NO release from endogenous donor of S-nitrosoglutathione (GSNO) in the presence of glutathione.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Dyeing and Modifying Textile Fibers · Skin Protection and Aging · melanin and skin pigmentation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (21)
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