Fabrication and biocompatibility of nano-TiO2/titanium alloys biomaterials

Abstract Using the process that titanium alloys were embedded by nanometer titanium dioxide powders and sintered in the high temperature furnace, the nano-TiO 2 /titanium alloys biomedical material was fabricated out. The particle size of TiO 2 particles on the surface of Ti alloy was mainly 50–90 nm. The experimental results indicated that the films of nanocrystalline titanium oxide powders on the surface of Ti alloy were with an excellent biocompatibility. By cultivation in the simulated body fluid (SBF) for 7 days, the Ca phosphates were deposited on the specimen surface; and n (Ca) / n (P) atom ratio is about 1.6 : 1, which is similar to that of HA and human bone.