Mesoporous bioactive glasses (MBGs) in cancer therapy: Full of hope and promise
Source abstract
Abstract
Abstract Implementing novel approaches for cancer therapy are under continuous progress, and bioactive glasses (BGs) and glass-ceramics show excellent potential in this regard. Although these materials have been mostly used as magnetic substances in hyperthermia approach, some of their subsets, i.e., mesoporous bioactive glasses (MBGs), have been recently proposed not only as magnetic materials but also as drug delivery systems for advanced treatment of bone cancer. Different types of MBGs including granular particles and three-dimensional (3D) scaffolds can be applied for cancer therapy. Based on the results obtained from in vitro studies, MBGs seem to have a bright future in the therapeutic strategies to combat cancer; however, their application in this field is still in its beginning, and more research needs to reveal all pros and cons of this newly proposed approach.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Layered Double Hydroxides Synthesis and Applications · Cervical and Thoracic Myelopathy
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (62)
Show source-provided references
1. Cassidy · 2015
2. Caffeine: cognitive and physical performance enhancer or psychoactive drug?10.2174/1570159X13666141210215655 ↗
3. Multifunctional magnetic mesoporous bioactive glass scaffolds with a hierarchical pore structure10.1016/j.actbio.2011.06.028 ↗
4. Synthesis, physico-chemical and biological characterization of strontium and cobalt substituted bioactive glasses for bone tissue engineering10.1016/j.jnoncrysol.2016.07.025 ↗
5. Gadolinium-doped bioglass scaffolds promote osteogenic differentiation of hBMSC via the Akt/GSK3β pathway and facilitate bone repair in vivo10.2147/IJN.S193576 ↗
6. In vitro cellular testing of Strontium/Calcium substituted phosphate glass discs and microspheres shows potential for bone regeneration10.1002/term.2796 ↗
7. Review of bioactive glass: from Hench to hybrids10.1016/j.actbio.2012.08.023 ↗
8. Regenerating bone with bioactive glass scaffolds: a review of in vivo studies in bone defect models10.1016/j.actbio.2017.08.030 ↗
9. Can bioactive glasses be useful to accelerate the healing of epithelial tissues?10.1016/j.msec.2019.01.028 ↗
10. Skin wound regeneration with bioactive glass-gold nanoparticles ointment10.1088/1748-605X/aafd7d ↗
11. Potential of bioactive glasses for cardiac and pulmonary tissue engineering10.3390/ma10121429 ↗
12. Bioactive glasses: special applications outside the skeletal system10.1016/j.jnoncrysol.2015.02.015 ↗
13. Boron-containing bioactive glasses in bone and soft tissue engineering10.1016/j.jeurceramsoc.2017.11.001 ↗
14. Synthesis and characterization of Barium-Iron containing magnetic bioactive glasses: the effect of magnetic component on structure and in vitro bioactivity
15. Stimulation of apoptotic pathways in liver cancer cells: an alternative perspective on the biocompatibility and the utility of biomedical glasses10.1177/0885328215621663 ↗
16. Unanticipated stabilization of zinc-silicate glasses by addition of lanthanum: implications for therapeutic inorganic ion delivery systems10.1016/j.jnoncrysol.2015.08.028 ↗
17. Yttrium-90 microsphere radioembolization for hepatocellular carcinoma10.1159/000343878 ↗
18. Outcomes of Therasphere radioembolization for colorectal metastases10.1016/j.clcc.2015.02.002 ↗
19. Copper-doped mesoporous bioactive glass for photothermal enhanced chemotherapy10.1166/jbn.2018.2542 ↗
20. Nanotechnology and Nanomedicine: start small, think big10.1016/j.matpr.2018.04.155 ↗
21. Bioactive glasses: where are we and where are we going?10.3390/jfb9010025 ↗
22. Glass-ceramics for cancer treatment: so close, or yet so far?10.1016/j.actbio.2018.11.013 ↗
23. Ordered mesoporous bioactive glasses for bone tissue regeneration10.1021/cm060488o ↗
24. Highly ordered mesoporous bioactive glasses with superior in vitro bone-forming bioactivities10.1002/anie.200460598 ↗
25. Well-ordered mesoporous bioactive glasses (MBG): a promising bioactive drug delivery system10.1016/j.jconrel.2005.11.002 ↗
26. A doxorubicin delivery system: samarium/mesoporous bioactive glass/alginate composite microspheres10.1016/j.msec.2016.05.019 ↗
27. Mesoporous bioactive glass-polyurethane nanocomposites as reservoirs for sustained drug delivery10.1016/j.colsurfb.2018.10.030 ↗
28. Synergistic combination of bioactive glasses and polymers for enhanced bone tissue regeneration10.1016/j.matpr.2018.04.160 ↗
29. Mesoporous nano-bioglass designed for the release of imatinib and in vitro inhibitory effects on cancer cells10.1016/j.msec.2017.03.288 ↗
30. Functional mesoporous bioactive glass nanospheres: synthesis, high loading efficiency, controllable delivery of doxorubicin and inhibitory effect on bone cancer cells10.1039/c3tb20275e ↗
31. Sol-gel derived terbium-containing mesoporous bioactive glasses nanospheres: in vitro hydroxyapatite formation and drug delivery10.1016/j.colsurfb.2017.09.051 ↗
32. C-dot generated bioactive organosilica nanospheres in theranostics: multicolor luminescent and photothermal properties combined with drug delivery capacity10.1021/acsami.6b07494 ↗
33. Mesoporous bioactive glasses: promising platforms for antibacterial strategies10.1016/j.actbio.2018.09.052 ↗
34. Targeted cancer therapy10.1038/nature03095 ↗
35. Preparation and characterization of mesoporous bioactive glass from agricultural waste rice husk for targeted anticancer drug delivery10.1016/j.ceramint.2016.11.007 ↗
36. Preparation, characterization, and in vitro evaluation of folate-modified mesoporous bioactive glass for targeted anticancer drug carriers10.1039/c3tb20867b ↗
37. Lanthanides: applications in cancer diagnosis and therapy: miniperspective10.1021/acs.jmedchem.5b01975 ↗
38. 153Sm-EDTMP for pain relief of bone metastases from prostate and breast cancer and other malignancies10.1016/j.arcmed.2014.03.006 ↗
39. Bioactive glasses as potential radioisotope vectors for in situ cancer therapy: investigating the structural effects of yttrium10.1039/c1cp21764j ↗
40. Plasmonic photothermal therapy (PPTT) using gold nanoparticles10.1007/s10103-007-0470-x ↗
41. Fundamentals and advances in magnetic hyperthermia10.1063/1.4935688 ↗
42. A review on potential benefits of hyperthermia in the treatment of cancer
43. Effective elimination of cancer stem cells by magnetic hyperthermia10.1021/mp400015b ↗
44. Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme10.1007/s11060-010-0389-0 ↗
45. One-pot synthesis of magnetic and mesoporous bioactive glass composites and their sustained drug release property10.1016/j.actamat.2008.03.013 ↗
46. Magnetic mesoporous bioactive glass scaffolds: preparation, physicochemistry and biological properties10.1039/c2tb00262k ↗
47. Preparation and characterization of magnetic mesoporous bioactive glass/carbon composite scaffolds10.1155/2013/893479 ↗
48. 3D-printed magnetic Fe 3 O 4/MBG/PCL composite scaffolds with multifunctionality of bone regeneration, local anticancer drug delivery and hyperthermia10.1039/C4TB01063A ↗
49. vitro evaluation of glass–glass ceramic thermoseed-induced hyperthermia on human osteosarcoma cell line10.1002/jbm.a.33229 ↗
50. In vitro bioactivity and stem cells attachment of three-dimensionally ordered macroporous bioactive glass incorporating iron oxides10.1016/j.jnoncrysol.2016.08.019 ↗
51. Magnetic phase transitions in macro/mesoporous bioactive glass by ferric nitrate addition in sol-gel synthesis
52. Fe-doped sol-gel glasses and glass-ceramics for magnetic hyperthermia10.3390/ma11010173 ↗
53. Fe-doped bioactive glass-derived scaffolds produced by sol-gel foaming10.1016/j.matlet.2018.10.042 ↗
54. Synthesis characterization, and in vitro biological evaluation of copper-containing magnetic bioactive glasses for hyperthermia in bone defect treatment
55. Surface engineering of iron oxide nanoparticles for targeted cancer therapy10.1021/ar2000277 ↗
56. Magnetic nanoparticles for cancer diagnosis and therapy10.1007/s11095-012-0679-7 ↗
57. Magnetic nanoparticles in cancer theranostics10.7150/thno.11544 ↗
58. A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics10.1016/j.biomaterials.2011.01.004 ↗
59. The effect of iron incorporation on the in vitro bioactivity and drug release of mesoporous bioactive glasses10.1016/j.ceramint.2013.01.094 ↗
60. Blockade of nuclear factor-κB (NF-κB) pathway inhibits growth and induces apoptosis in chemoresistant ovarian carcinoma cells10.1016/j.biocel.2018.03.015 ↗
61. Angiogenesis in cancer10.2147/vhrm.2006.2.3.213 ↗
62. VEGF121-conjugated mesoporous silica nanoparticle: a tumor targeted drug delivery system10.1021/am506849p ↗