A simple recipe for direct writing complex 45S5 Bioglass® 3D scaffolds
Source abstract
Abstract
Abstract Direct-writing fabrication techniques, such as robocasting, have been ignored up to date for the production of scaffolds from 45S5 Bioglass ® , probably due to difficulties in the preparation of stable high solids loading colloidal suspensions (inks) from 45S5 Bioglass ® powders using traditional approaches. Here, we report how these difficulties can be overcome. Aqueous suspensions containing 45 vol% of 45S5 Bioglass ® were successfully prepared using carboxymethyl cellulose (CMC) as single multifunctional (dispersant, binder, gelation agent) processing additive. Playing with the molecular weight (MW) and amount of CMC enabled tuning the rheological properties of the inks to meet the stringent requirements of robocasting. An incomplete surface coverage allowing bridging flocculation to occur is the key to obtain highly performing inks.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Facial Trauma and Fracture Management · Additive Manufacturing and 3D Printing Technologies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (23)
Show source-provided references
1. Bonding mechanisms at the interface of ceramic prosthetic materials10.1002/jbm.820050611 ↗
2. Sintering and crystallisation of 45S5 Bioglass® powder10.1016/j.jeurceramsoc.2009.06.035 ↗
3. The story of Bioglass®10.1007/s10856-006-0432-z ↗
4. Glass and medicine10.1111/j.2041-1294.2010.00001.x ↗
5. Bioactive glass and glass-ceramic scaffolds for bone tissue engineering10.3390/ma3073867 ↗
6. Processing of 45S5 Bioglass® by lithography-based additive manufacturing10.1016/j.matlet.2012.01.019 ↗
7. Three-dimensional bioactive glass implants fabricated by rapid prototyping based on CO2 laser cladding10.1016/j.actbio.2011.05.023 ↗
8. Three-dimensional printing of hierarchical and tough mesoporous bioactive glass scaffolds with a controllable pore architecture, excellent mechanical strength and mineralization ability10.1016/j.actbio.2011.03.009 ↗
9. Meszaros · Three-Dimensional Print Bioactive Glass · 2011 · 111
10. Cracking in ceramic/metal/polymer trilayer systems10.1557/JMR.2002.0163 ↗
11. Porous and strong bioactive glass (13–93) scaffolds fabricated by freeze extrusion technique.10.1016/j.msec.2011.06.004 ↗
12. Direct ink writing of highly porous and strong glass scaffolds for load-bearing bone defects repair and regeneration10.1016/j.actbio.2011.06.030 ↗
13. Robocasting provides moldless fabrication from slurry deposition
14. Sintering and robocasting of beta-tricalcium phosphate scaffolds for orthopaedic applications10.1016/j.actbio.2006.02.004 ↗
15. Bioactive glass scaffolds for bone tissue engineering: state of the art and future perspectives10.1016/j.msec.2011.04.022 ↗
16. Iler · 1979
17. An electrokinetic study of the interactions between glass-fibers and aqueous-solutions of calcium10.1016/0021-9797(82)90166-7 ↗
18. Acid behavior of carboxylic derivatives of cellulose.1. Carboxymethyl cellulose10.1002/pol.1963.100010911 ↗
19. Biphasic calcium phosphate nanocomposite porous scaffolds for load-bearing bone tissue engineering10.1016/j.biomaterials.2003.12.023 ↗
20. Adsorption of partially hydrolyzed polyacrylamides on titanium-dioxide10.1016/0021-9797(88)90430-4 ↗
21. 45S5 Bioglass ®-derived glass-ceramic scaffolds for bone tissue engineering10.1016/j.biomaterials.2005.11.025 ↗
22. Abarrategi A, Moreno-Vicente C, Martinez-Vazquez FJ, Civantos A, Ramos V, Sanz Casado JV., et al. Biological properties of solid free form designed ceramic scaffolds with BMP-2: in vitro and in vivo evaluation, 2012.10.1371/journal.pone.0034117 ↗
23. Multiscale osteointegration as a new paradigm for the design of calcium phosphate scaffolds for bone regeneration10.1016/j.biomaterials.2010.01.052 ↗