journal article·2026-07Open access

Injectable hydrogel with sequential drug release for synergistic antibacterial activity and osteogenesis in infected bone defects

Shouye Sun, Zhaochangci Chen, Qian Wang, Yutao Cui, Hang Xu, Baoming Yuan, Yangbing Wang, Dankai Wu, Chuangang Peng

Materials & Design· Volume 267

Abstract

• Antibiotic-free injectable PEG/ODEX hydrogel for infected bone defect repair. • Sequential release of lysozyme and BMP-2-derived peptide via the hydrogel system • Synergistic bactericidal effect and pro-osteogenic activity of the bifunctional hydrogel. • Enhanced bone regeneration in murine femoral infected bone defect model.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Orthopedic Infections and Treatments · Bone Tissue Engineering Materials · Graphene and Nanomaterials Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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