RNA-modified carbon nanotube arrays recognizing RNA via electrochemical capacitance response
Source abstract
Abstract
Abstract Electrochemically active hybrid electrodes have been obtained by non-covalent immobilization of homo-oligoribonucleotide probes on the surface of multi-walled carbon nanotubes (MWCNTs) grown vertically on a silicon substrate. Immobilization has been achieved by interaction of heterocyclic bases of oligonucleotide with MWCNT surface or through a pyrene anchor group pre-conjugated to oligonucleotide. The electrode capacitance signal measured in our model system allowed for the selective recognition of target RNA oligonucleotides. Pyrene-anchoring of oligonucleotide probes to the MWCNT surface was shown to provide the better selectivity and stability of electrochemical response of the hybrid electrode.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Carbon Nanotubes in Composites · Conducting polymers and applications · Electrochemical Analysis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (37)
Show source-provided references
1. A review on technological aspects influencing commercialization of carbon nanotube sensors10.1016/j.snb.2011.03.040 ↗
2. Advances in carbon nanotube based electrochemical sensors for bioanalytical applications10.1016/j.biotechadv.2010.10.002 ↗
3. Recent developments in carbon nanomaterial sensors10.1039/C4CS00379A ↗
4. Electrochemical sensors and biosensors based on redox polymer/carbon nanotube modified electrodes: a review10.1016/j.aca.2015.02.059 ↗
5. Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: a review10.1016/j.aca.2015.05.049 ↗
6. Comparative study of the electrochemical behavior and analytical applications of (bio)sensing platforms based on the use of multi-walled carbon nanotubes dispersed in different polymers10.1016/j.aca.2013.10.039 ↗
7. Advances in carbon-nanotube assembly10.1002/smll.200600354 ↗
8. Orientated assembly of single-walled carbon nanotubes and applications10.1039/b702080e ↗
9. Electrochemical double layer capacitor electrodes using aligned carbon nanotubes grown directly on metals10.1088/0957-4484/20/39/395202 ↗
10. Vertically aligned single-walled carbon nanotubes by chemical assembly — methodology, properties, and applications10.1002/adma.200903592 ↗
11. Carbon nanotubes: present and future commercial applications10.1126/science.1222453 ↗
12. Carbon nanotubes and nanowires for biological sensing
13. Carbon nanotube-based electrochemical biosensing platforms: fundamentals, applications and future possibilities10.2174/187220807780809427 ↗
14. Non-covalent immobilization of oligonucleotides on single-walled carbon nanotubes
15. Nanomaterial-based electrochemical DNA sensing strategies10.1016/j.talanta.2007.10.012 ↗
16. Electrochemistry of nucleic acids10.1021/cr200303p ↗
17. Carbon nanotubes for electrochemical biosensing10.1016/j.talanta.2007.10.013 ↗
18. Use of nanomaterials for impedimetric DNA sensors: a review10.1016/j.aca.2010.08.022 ↗
19. Site-specific assembly of DNA and appended cargo on arrayed carbon nanotubes10.1021/ja045543d ↗
20. Single-walled carbon nanotube biosensors using aptamers as molecular recognition elements10.1021/ja053094r ↗
21. Label-free protein biosensor based on aptamer-modified carbon nanotube field-effect transistors10.1021/ac060830g ↗
22. Label-free detection of DNA hybridization using pyrene-functionalized single-walled carbon nanotubes: effect of chemical structures of pyrene molecules on DNA sensing performance10.1166/jnn.2011.3663 ↗
23. Fluorecently labelled single-walled carbon nanotubes and their hybrids with oligonucleotides10.1134/S1995078012020024 ↗
24. Novel multifunctional hybrids of single-walled carbon nanotubes with nucleic acids: synthesis and interactions with living cells10.1021/am4034729 ↗
25. Synthesis and structure of films consisting of carbon nanotubes oriented normally to the substrate10.1134/S1063784207120183 ↗
26. Oligo(2′-O-methylribonucleotides) and their derivatives: III. 5′-Mono- and 5′-bispyrenyl derivatives of oligo(2′–O-methylribonucleotides) and their 3′-modified analogues: synthesis and properties10.1134/S1068162008050105 ↗
27. Stöhr · 1992
28. Electronic structure of the nucleobases10.1021/jp0463058 ↗
29. Electronic structure of genomic DNA: a photoemission and X-ray absorption study10.1021/jp1013237 ↗
30. Adsorption of poly(rA) on the carbon nanotube surface and its hybridization with poly(rU).10.1002/cphc.200800182 ↗
31. Unzipping and binding of small interfering RNA with single walled carbon nanotube: a platform for small interfering RNA delivery10.1063/1.3682780 ↗
32. Detection of influenza A virus based on fluorescence resonance energy transfer from quantum dots to carbon nanotubes10.1016/j.aca.2012.02.030 ↗
33. DNA–carbon nanotube interactions and nanostructuring based on DNA10.1002/pssb.200776108 ↗
34. Readily reusable electrochemical DNA hybridization biosensor based on the interaction of DNA with single-walled carbon nanotubes10.1021/ac802026j ↗
35. Dissociation of single-strand DNA: single-walled carbon nanotube hybrids by Watson-Crick base-pairing10.1021/ja102673m ↗
36. Combined Raman scattering and ab initio investigation of the interaction between pyrene and carbon SWNT10.1080/0026897031000154284 ↗
37. SWNT–DNA and SWNT–polyC hybrids: AFM study and computer modeling10.1166/jnn.2008.18214 ↗