Development of a Novel Cyclodextrin–Chitosan Polymer for an Efficient Removal of Pharmaceutical Contaminants in Aqueous Solution
Source abstract
Abstract
A novel polymer synthesized by grafting three cyclodextrins onto chitosan was characterized and evaluated for its potential to adsorb two pharmaceutical residues: ibuprofen and progesterone. The influence of various operational parameters, including contact time, initial molecule concentration, pH, ionic strength, and temperature, was investigated. The synthesized polymer exhibits an amorphous and porous structure with a remarkable swelling capacity of 9.5 mmol/g. It demonstrates remarkable adsorption capacities for progesterone and ibuprofen, reaching 90% and 75%, respectively. Kinetic studies reveal that the adsorption of both molecules follows a pseudo-second-order model. A DSC analysis elucidated the adsorption mechanism, which is governed by the formation of inclusion complexes and electrostatic interactions within the polymer network. The polymer’s regeneration after 23 cycles demonstrates its sustainable adsorption efficiency. The combination of chitosan with three cyclodextrins opens up promising new avenues for water treatment and the removal of specific pollutants. This approach significantly improves the material’s selectivity towards target pollutants, offering a significant advantage in pollution remediation applications.
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Research context
OpenAlex topics: Adsorption and biosorption for pollutant removal · Analytical chemistry methods development · Pharmaceutical and Antibiotic Environmental Impacts
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
UNIROUEN, Galenic Pharmaceutical Laboratory, NorDIC Inserm U1239, UFR Medicine and Pharmacy, Rouen University, Normandie Univ, 22 Bd Gambetta, F-76183 Rouen, France
Laboratory of Membrane Processes and of Separation and Recovery Techniques, Faculty of Technology, Abderrahmane Mira University, Route de Targua Ouzemmour, Bejaia 06000, Algeria
Faculty of Science and Applied Sciences, Department of Process Engineering, Akli Mohand Oulhadj University, Bouira 10000, Algeria
Institute of Technology, Department of Process Engineering, Akli Mohand Oulhadj University, Bouira 10000, Algeria
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