Surface Studies on a Model Cell-Resistant System
Source abstract
Abstract
A model system involving a polyanionic alginic acid (AA) overlayer ionically immobilized on a polycationic polyethyleneimine underlayer, in turn linked to plasma oxidized polystyrene, was used to investigate the relationship between surface structure properties and resistance to cell adhesion. X-ray Photoelectron Spectroscopy (XPS) and water contact angle measurement were used to characterize the surfaces and to compare the results with data on resistance to adhesion of L-929 fibroblasts. A overlayer model was used to account for the XPS results in terms of fractional coverage by AA. Results show the strong effect of the surface density of AA chains on resistance to cell adhesion and underline the inadequacy of simple relationships between wettability by water and cell adhesion.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Polymer Surface Interaction Studies · Advanced Polymer Synthesis and Characterization · Surface Modification and Superhydrophobicity
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Nobil Bio Ricerche, Str. S. Rocco 32, 14018 Villafranca d'Asti, Italy
References (36)
Show source-provided references
1. Vacanti C. A. · Tissue Eng. · 1995 · 1 · 310.1089/ten.1995.1.3 ↗
2. Ratner B. D. · J. Biomed. Mater. Res. · 1993 · 27 · 83710.1002/jbm.820270702 ↗
3. Horbett, T. A.; Klumb, L. A. InInterfacial Phenomena andBioproducts; Brash, J. L., Wojciechowski, P. W., Eds; Marcel Dekker: New York, 1996; p 351.
4. Tamada Y. · J. Biomed. Mater. Res. · 1994 · 28 · 78310.1002/jbm.820280705 ↗
5. Lydon M. J. · J. Biomaterials · 1985 · 6 · 39610.1016/0142-9612(85)90100-0 ↗
6. Rollason G. · Biomaterials · 1993 · 14 · 15310.1016/0142-9612(93)90230-Y ↗
7. Desai N. P. · J. Biomed. Mater. Res. · 1991 · 25 · 82910.1002/jbm.820250704 ↗
8. Nagaoka S. · ASAIO J. · 1987 · 10 · 7610.1097/00002480-198704000-00006 ↗
9. Szleifer I. · Phys. A · 1997 · 244 · 37010.1016/S0378-4371(97)00293-8 ↗
10. Jeon S. J. · J. Colloid Interface Sci. · 1991 · 142 · 14910.1016/0021-9797(91)90043-8 ↗
11. Jeon S. J. · J. Colloid Interface Sci. · 1991 · 142 · 15910.1016/0021-9797(91)90044-9 ↗
12. Lopez G. P. · J. Biomed. Mater. Res. · 1992 · 26 · 41510.1002/jbm.820260402 ↗
13. Prime K. L. · J. Am. Chem. Soc. · 1993 · 23 · 1071410.1021/ja00076a032 ↗
14. Osterberg E. · J. Biomed. Mater. Res. · 1995 · 29 · 74110.1002/jbm.820290610 ↗
15. Brink C. · Colloids Surf. · 1992 · 66 · 14910.1016/0166-6622(92)80131-K ↗
16. Morra M. · 1996
17. Pavesio A. · Med. Dev. Technol. · 1997 · 8 · 20
18. Golander, G. C.; Herron, J. N.; Lim., K.; Claesson, P.; Stenius, P.; Andrade, J. D. InPoly(Ethylene Glycol) Chemistry: Biotechnical andBiomedical Applications; Harris, J. M., Ed.; Plenum Press: New York, 1992; p 221.10.1007/978-1-4899-0703-5_15 ↗
19. Irvine D. J. · J. Biomed. Mater. Res. · 1998 · 40 · 49810.1002/(SICI)1097-4636(19980605)40:3<498::AID-JBM21>3.0.CO;2-E ↗
20. Larm O. · Biomater. Med. Dev. Art. Org. · 1983 · 161 · 11
21. Narayanan P. V. · J. Biomater. Sci., Polym. Ed. · 1994 · 6 · 111
22. Qin Y. · Med. Dev. Technol. · 1996 · 7 · 32
23. Morra M. · Surface Interface Anal. · 1998 · 26 · 74210.1002/(SICI)1096-9918(199809)26:10<742::AID-SIA417>3.0.CO;2-P ↗
24. Briggs D. · 1992 · 1
25. Golander G. C. · J. Colloid Interface Sci. · 1987 · 119 · 3810.1016/0021-9797(87)90242-6 ↗
26. Chance J. J. · Langmuir · 1997 · 13 · 448710.1021/la970081l ↗
27. West R. H. · J. Mater. Sci. Mater. Med. · 1995 · 6 · 6310.1007/BF00120408 ↗
28. Rau D. C. · Science · 1990 · 249 · 127810.1126/science.2144663 ↗
29. Brady J. W. · J. Phys. Chem. · 1993 · 97 · 95810.1021/j100106a024 ↗
30. Johnson S. D. · J. Biomed. Mater. Res. · 1992 · 26 · 91510.1002/jbm.820260707 ↗
31. Besseling N. A. M. · Langmuir · 1997 · 13 · 211310.1021/la960672w ↗
32. Van Oss C. J. · 1994
33. Morra M. · J. Colloid Interface Sci. · 1996 · 182 · 31210.1006/jcis.1996.0469 ↗
34. Morra M. · J. Biomed. Sci., Polym. Ed. · 1997 · 9 · 5510.1163/156856297X00263 ↗
35. Della Volpe C. · J. Colloid Interface Sci. · 1997 · 195 · 12110.1006/jcis.1997.5124 ↗
36. Lee L. H. · Langmuir · 1996 · 12 · 168110.1021/la950725u ↗