A Bio-inspired, Thrombus-Mimetic Architecture in Liquid Metal Strain Sensors Achieving Ultra-High Sensitivity and Wide Range Response
Source abstract
Abstract
Abstract This paper presents a bio-inspired liquid metal strain sensor achieving high sensitivity and wide sensing range through a localized flow-limiting design. By integrating rigid PDMS inserts into a soft Ecoflex matrix, tensile strain induces local microchannel constriction, producing exponential resistance changes. The sensor delivers a gauge factor (GF) of 0.343 at 0–50% strain (36-fold enhancement) and 296 at 130–150% strain (15,000-fold enhancement), along with a pressure sensitivity of 19.1 MPa–1 (922-fold enhancement). It maintains excellent stability with only 1.5% resistance degradation after 300 cycles. Through pre-stretching to access the high-sensitivity regime, the sensor successfully demonstrates voice recognition, pulse waveform analysis capable of distinguishing "Cun-Guan-Chi" pulse positions, and gesture-based robotic control. This work provides an effective strategy for developing high-performance flexible sensors for healthcare monitoring and human–machine interaction applications.
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Research context
OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Soft Robotics and Applications · Advanced Materials and Mechanics
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Xiamen University , , , ,
Shenzhen Research Institute of Xiamen University , ,
Funding
Basic and Applied Basic Research Foundation of Guangdong Province · Natural Science Foundation of Xiamen Municipality · National Natural Science Foundation of China (NSFC)
References (48)
Show source-provided references
1. Technology Roadmap for Flexible Sensors10.1021/acsnano.2c12606 ↗
2. One-Step-Printed, Highly Sensitive, Textile-Based, Tunable Performance Strain Sensors for Human Motion Detection10.1002/admt.201900925 ↗
3. A disposable, wearable, flexible, stitched textile electrochemical biosensing platform10.1016/j.Bios.2021.113604 ↗
4. Single fibre enables acoustic fabrics via nanometre-scale vibrations10.1038/s41586-022-04476-9 ↗
5. High-sensitivity and self-powered flexible pressure sensor based on multi-scale structured piezoelectric composite10.1016/j.Cej.2025.164787 ↗
6. Deformation-adaptive pressure sensors based on multi-level discrete sensing arrays for morphing electronics and human–machine interaction10.1038/s41528-025-00522-4 ↗
7. Vascular smooth muscle-inspired architecture enables soft yet tough self-healing materials for durable capacitive strain-sensor10.1038/s41467-023-35810-y ↗
8. A facile and scalable patterning approach for ultrastretchable liquid metal features10.1039/d2lc00872f ↗
9. Bovine rumen inspired multiple-nested porous aerogel pressure sensor with high sensitivity and wide detection range10.1016/j.Snb.2025.139291 ↗
10. A review of flexible strain sensors for walking gait monitoring10.1016/j.sna.2024.115730 ↗
11. Polymer-based strain sensors: review10.1007/s10854-024-12923-8 ↗
12. Recent Advances in Liquid Metal-Based Stretchable and Conductive Composites for Wearable Sensor Applications10.3390/bios15070466 ↗
13. Superhydrophobic MXene-CNT Bridge Strain Sensors with Wide Linear-Range via Strain-isolation and Crack-synergy Effects10.1016/j.Cej.2024.150796 ↗
14. Surface Wettability for Skin-Interfaced Sensors and Devices10.1002/adfm.202200260 ↗
15. Three-dimensional cracks architectural design enhances the sensitivity and stretchability of superhydrophobic strain sensors10.1016/j.Compositesb.2024.111978 ↗
16. Toward flexible piezoresistive strain sensors based on polymer nanocomposites: a review on fundamentals, performance, and applications10.1088/1361-6528/ad3e87 ↗
17. Liquid Metal-Based Soft Electronics for Wearable Healthcare10.1002/adhm.202002280 ↗
18. Liquid Metal-Based Frequency and Pattern Reconfigurable Yagi Antenna for Pressure Sensing10.3390/s25051498 ↗
19. Shape-adaptive electronics based on liquid metal circuits printed on thermoplastic films10.1038/s41928-025-01528-6 ↗
20. An Antiferroelectric-Coated Metal Foam Infiltrated with Liquid Metal as a Dielectric Capacitor10.1002/ente.202400956 ↗
21. Implantable Soft Neural Electrodes of Liquid Metals for Deep Brain Stimulation10.1021/acsnano.4c18030 ↗
22. Overview of progress of liquid metal applications in nanomaterials, flexible electronics and new energy10.1080/19475411.2024.2400932 ↗
23. Precision-controlled sequential drug release via electrochemical corrosion of liquid metal nanoparticles10.1126/sciadv.Adw6986 ↗
24. Gallium-based nano-liquid metals enabled antimicrobial mechanisms and biomedical applications10.1039/d5nr00406c ↗
25. Triboelectric nanogenerator with liquid metal electrode surface microarray structure for self-powered bidirectional sensing and energy harvester10.1016/j.mtcomm.2025.112151 ↗
26. Emerging roles of liquid metals in carbon neutrality10.1007/s11708-022-0829-5 ↗
27. Miniaturized Liquid Metal Composite Circuits with Energy Harvesting Coils for Battery-Free Bioelectronics and Optogenetics10.1002/adfm.202417053 ↗
28. Eutectic Gallium-Indium (EGaIn): A Liquid Metal Alloy for the Formation of Stable Structures in Microchannels at Room Temperature10.1002/adfm.200701216 ↗
29. Smart Eutectic Gallium–Indium: From Properties to Applications10.1002/adma.202203391 ↗
30. Liquid-Metal-Based Multichannel Strain Sensor for Sign Language Gesture Classification Using Machine Learning10.1021/acsami.4c19102 ↗
31. Ma · ACS Macro Lett. · 2019 · 8 · 152210.1021/acsmacrolett.9b00783 ↗
32. Gallium Nanodroplets are Anti-Inflammatory without Interfering with Iron Homeostasis10.1021/acsnano.1c10981 ↗
33. Soft Miniaturized Actuation and Sensing Units for Dynamic Force Control of Cardiac Ablation Catheters10.1089/soro.2019.0011 ↗
34. Liquid Metal and Carbon Nanofiber-Based Strain Sensor for Monitoring Gesture, Voice, and Physiological Signals10.1021/acsanm.3c04764 ↗
35. Compression-Durable Soft Electronic Circuits Enabled by Embedding Self-Healing Biphasic Liquid-Solid Metal Into Microstructured Elastomeric Channels10.1002/adma.202420469 ↗
36. Advances in micro/nano-engineered flexible sensor arrays for intelligent human-machine interaction10.20517/ss.2025.11 ↗
37. Bioinspired robot skin with mechanically gated electron channels for sliding tactile perception10.1126/sciadv.Ade0720 ↗
38. Comparison of flexible strain sensors based on liquid metals with different microchannel structures10.1088/1361-6501/ada822 ↗
39. Conductive liquid-based multimodal flexible sensor for self-decoupled strain and temperature measurement10.1016/j.Measurement.2025.119064 ↗
40. Biomimetic three-dimensional microchannel non-destructive self-healing flexible strain sensor based on liquid metal-polydimethylsiloxane elastomer10.1016/j.Cej.2024.154526 ↗
41. A novel liquid metal sensor with three microchannels embedded in elastomer10.1088/1361-665X/ab7433 ↗
42. Design of A Flexible Liquid Metal Tactile Sensor Based on Finite Element Analysis for Pressure and Motion Detection10.1002/aelm.202500124 ↗
43. Precision aerosol-jet micropatterning of liquid metal for high-performance flexible strain sensors10.1038/s41467-025-63023-y ↗
44. Flexible liquid metal-based microfluidic strain sensors with fractal-designed microchannels for monitoring human motion and physiological signals10.1016/j.Bios.2023.115905 ↗
45. Nacre-Inspired, Liquid Metal-Based Ultrasensitive Electronic Skin by Spatially Regulated Cracking Strategy10.1002/adfm.202102359 ↗
46. The relationship between the Young’s modulus and dry etching rate of polydimethylsiloxane (PDMS)10.1007/s10544-019-0379-8 ↗
47. Modulus and adhesion of Sylgard 184, Solaris, and Ecoflex 00-30 silicone elastomers with varied mixing ratios10.1002/app.52412 ↗
48. A Comprehensive Experimental, Simulation, and Characterization Mechanical Analysis of Ecoflex and Its Formulation Under Uniaxial Testing10.3390/ma18133037 ↗