journal article·2019-11

3D structures of hydroxyapatite obtained from Rapana venosa shells using hydrothermal synthesis followed by 3D printing

Ana Maria Mocioiu, Raluca Tutuianu, Laura Madalina Cursaru, Roxana Mioara Piticescu, Paul Stanciu, Bogdan Stefan Vasile, Roxana Trusca, Viviana Sereanu, Aurelia Meghea

Journal of Materials Science· Volume 54· Issue 22
Publisher page

Abstract

In this study, hydroxyapatite (HAp) obtained by hydrothermal synthesis from natural sources (whelk shells of Rapana thomasiana) was compared to synthetic hydroxyapatite (prepared from chemical reagents) and used for 3D printing of HAp-based structures. Rapana thomasiana can be found in Romanian coast of Black Sea. The visceral part of Rapana is used for culinary purposes, but the whelk shell, mainly consisting of CaCO3, remains as biowaste and can be used as a source of Ca for hydroxyapatite synthesis. Synthetic and natural hydroxyapatite nanopowders were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), dynamic light scattering (DLS) method and in vitro tests. XRD and FT-IR have confirmed the formation of nanostructured hydroxyapatite irrespective of the raw material used. Both types of powders were further used for 3D printing of HAp-based structures, which have also been characterized by SEM and in vitro tests. In vitro tests performed on natural HAp disks (made from whelk shell) lack cytotoxicity and were associated with cell viability similar to that for the synthetic hydroxyapatite disk.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Bone Tissue Engineering Materials · Dental Implant Techniques and Outcomes · Additive Manufacturing and 3D Printing Technologies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (34)

Show source-provided references
1. Szczes A, Holysz L, Chibowski E (2017) Synthesis of hydroxyapatite for biomedical applications. Adv Coll Interface Sci 249:321–33010.1016/j.cis.2017.04.007 ↗
2. Turk S, Altinsoy I, CelebiEfe G et al (2017) Microwave-assisted biomimetic synthesis of hydroxyapatite using different sources of calcium. Mater Sci Eng, C 76:528–53510.1016/j.msec.2017.03.116 ↗
3. Shi P, Liu M, Fan F et al (2018) Characterization of natural hydroxyapatite originated from fish bone and its biocompatibility with osteoblasts. Mater Sci Eng, C 90:706–71210.1016/j.msec.2018.04.026 ↗
4. Titsinides S, Agrogiannis G, Karatzas T (2019) Bone grafting materials in dentoalveolar reconstruction: a comprehensive review. Jpn Dent Sci Rev 55(1):26–3210.1016/j.jdsr.2018.09.003 ↗
5. Ferro AC, Guedes M (2019) Mechanochemical synthesis of hydroxyapatite using cuttlefish bone and chicken eggshell as calcium precursors. Mater Sci Eng, C 97:124–14010.1016/j.msec.2018.11.083 ↗
6. Rustom LE, Poellmann MJ, Wagoner Johnson AJ (2019) Mineralization in micropores of calcium phosphate scaffolds. Acta Biomater 83:435–45510.1016/j.actbio.2018.11.003 ↗
7. Hench LL, Wilson J (1993) An introduction to bioceramics. World Scientific, Singapore10.1142/2028 ↗
8. Sanli I, Arts JJC, Geurts J (2016) Clinical and radiologic outcomes of a fully hydroxyapatite-coated femoral revision stem: excessive stress shielding incidence and its consequences. J Arthroplasty 31:209–21410.1016/j.arth.2015.08.037 ↗
9. Barrere-de Groot F, Yuan H, de Bruijn JD (2018) Clinical relevance of sub-micron textured calcium phosphates for bone tissue regeneration. Mater Today Proc 5:15501–1550510.1016/j.matpr.2018.04.156 ↗
10. Moles A, Heudes PM, Amelot A et al (2018) Long-term follow-up comparative study of hydroxyapatite and autologous cranioplasties: complications, cosmetic results, osseointegration. World Neurosurg 111:e395–e40210.1016/j.wneu.2017.12.082 ↗
11. Zhang B, Pei X, Song P et al (2018) Porous bioceramics produced by inkjet 3D printing: effect of printing ink formulation on the ceramic macro and micro porous architectures control. Compos B 155:112–12110.1016/j.compositesb.2018.08.047 ↗
12. Latocha J, Wojasinski M, Jurczak K et al (2018) Precipitation of hydroxyapatite nanoparticles in 3D-printed reactors. Chem Eng Process 133:221–23310.1016/j.cep.2018.10.001 ↗
13. Leukers B, Gulkan H, Irsen SH et al (2005) Hydroxyapatite scaffolds for bone tissue engineering made by 3D printing. J Mater Sci - Mater Med 16:1121–112410.1007/s10856-005-4716-5 ↗
14. Raymond S, Maazouz Y, Montufar EB et al (2018) Accelerated hardening of nanotextured 3D-plotted self-setting calcium phosphate inks. Acta Biomater 75:451–46210.1016/j.actbio.2018.05.042 ↗
15. Shao H, He J, Lin T et al (2019) 3D gel-printing of hydroxyapatite scaffolds for bone tissue engineering. Ceram Int 45:1163–117010.1016/j.ceramint.2018.09.300 ↗
16. Roopavath UK, Malferrari S, Van Haver A et al (2019) Optimization of extrusion based ceramic 3D printing process for complex bony designs. Mater Des 162:263–27010.1016/j.matdes.2018.11.054 ↗
17. Chen S, Shi Y, Zhang X, Ma J (2019) 3D printed hydroxyapatite composite scaffolds with enhanced mechanical properties. Ceram Int 45:10991–1099610.1016/j.ceramint.2019.02.182 ↗
18. Lalzawmliana V, Anand A, Mukherjee P et al (2019) Marine organisms as a source of natural matrix for bone tissue engineering. Ceram Int 45:1469–148110.1016/j.ceramint.2018.10.108 ↗
19. Alif MF, Aprillia W, Arief S (2018) A hydrothermal synthesis of natural hydroxyapatite obtained from Corbicula moltkiana freshwater clams shell biowaste. Mater Lett 230:40–4310.1016/j.matlet.2018.07.034 ↗
20. Rujitanapanich S, Kumpapan P, Wanjanoi P (2014) Synthesis of hydroxyapatite from oyster shell via precipitation. Energy Proc 56:112–11710.1016/j.egypro.2014.07.138 ↗
21. Yakamura H, Pereira da Silva VH, Menin Ruiz PL et al (2018) Physico-chemical characterization and biocompatibility of hydroxyapatite derived from fish waste. J Mech Behav Biomed Mater 80:137–14210.1016/j.jmbbm.2018.01.035 ↗
22. Ayatollahia MR, Yahya MY, Shirazi HA et al (2015) Mechanical and tribological properties of hydroxyapatite nanoparticles extracted from natural bovine bone and the bone cement developed by nano-sized bovine hydroxyapatite filler. Ceram Int 41:10818–1082710.1016/j.ceramint.2015.05.021 ↗
23. Sereanu V, Meghea I, Vasile GG, Mihai M (2018) Environmental influence on Rapana venosa shell morphotypes and phenotypes from the Romanian Black Sea Coast. Rev Chim 69(1):50–5610.37358/RC.18.1.6043 ↗
24. Okada M, Matsumoto T (2015) Synthesis and modification of apatite nanoparticles for use in dental and medical applications. Jpn Dent Sci Rev 51:85–9510.1016/j.jdsr.2015.03.004 ↗
25. Byrappa K, Yoshimura M (2011) Handbook of hydrothermal technology. A technology for crystal growth and materials processing. Noyes Publications, Park Ridge, New Jersey, USA/William Andrew Publishing, LLC, Norwich, New York, USA
26. Gradinaru S, Popescu LM, Piticescu RM et al (2016) Repair of the orbital wall fractures in rabbit animal model using nanostructured hydroxyapatite-based implant. Nanomaterials 6(1):11. https://doi.org/10.3390/nano601001110.3390/nano6010011 ↗
27. Piticescu RM, Cursaru LM, Ciobota DN et al (2019) 3D bioprinting of hybrid materials for regenerative medicine: implementation in innovative small and medium-sized enterprises (SMEs). JOM J Miner Met Mater Soc 71(2):662–67210.1007/s11837-018-3252-y ↗
28. Prakasam M, Popescu M, Piticescu R et al (2017) Fabrication methodologies of biomimetic and bioactive scaffolds for tissue engineering applications. In: Baino F (ed) Scaffolding in bioengineering-materials, technologies, clinical applications. IntechOpen, Rijeka, pp 3–30
29. Popescu LM, Piticescu RM, Motoc AM, et al Romanian Patent no. 132753/30.05.2019
30. Popescu LM, Piticescu RM, Motoc AM, et al European Patent Application EP 3366319/29.08.2018
31. Yang Y, Yao Q, Pu X et al (2011) Biphasic calcium phosphate macroporous scaffolds derived from oyster shells for bone tissue engineering. Chem Eng J 173:837–84510.1016/j.cej.2011.07.029 ↗
32. Kamalanathan P, Ramesh S, Bang LT et al (2014) Synthesis and sintering of hydroxyapatite derived from eggshells as a calcium precursor. Ceram Int 40:16349–1635910.1016/j.ceramint.2014.07.074 ↗
33. Sereanu V, Feraru D-L, Predeanu G et al (2017) Microstructure and chemical characterization of Rapana thomasiana shell. UPB Sci Bull Ser B Chem Mater Sci 79(1):81–92
34. Alif MF, Aprillia W, Arief S (2018) A hydrothermal synthesis of natural hydroxyapatite obtained from Corbicula moltkiana freshwater clams shell biowaste. Mater Lett 230:40–4310.1016/j.matlet.2018.07.034 ↗