journal article·2022-02

Biofunctionalization of graphene and its two-dimensional analogues and synthesis of biomimetic materials: a review

Shuhan Di, Yuhong Qian, Li Wang, Zhuang Li

Journal of Materials Science· Volume 57· Issue 5
Publisher page

Abstract

Two-dimensional (2D) materials have become a “rising star” in the eyes of scientists because of their designability, manipulability, and ease of functionalization. When the 2D materials are modified by biomolecules in a covalent or non-covalent ways, some properties of the materials surface will change accordingly, making them have the properties of both the material and the biological macromolecules used for modification. Biomolecules attached to the surface of 2D materials can improve the bioactivity and biocompatibility of the obtained biocomposites, which makes the application of 2D materials more extensive. In this work, we introduce the interaction processes of the graphene and its derivatives, transition metal dichalcogenide materials (TMDs), and hexagonal boron nitride (h-BN) with biological macromolecules such as DNA and proteins. In addition, we also summarize the method of synthesizing bionic materials by using the composite materials with biofunctions and their important applications in biomineralization, biomedicine, environmental engineering, and materials engineering. We hope that this review can help readers to make sense of the principles and methods of biofunctionalization of 2D materials, understand the interactions between 2D materials and biomolecules at the molecular level, design biofunctionalized 2D materials to obtain bionanomaterials with special properties, and promote the applications and research in various fields such as biomedicine.
Source: expertdata · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Graphene and Nanomaterials Applications · Graphene research and applications · MXene and MAX Phase Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (100+)

Show source-provided references
1. Cai XK, Luo YT, Liu BL, Cheng HM (2018) Preparation of 2D material dispersions and their applications. Chem Soc Rev 47:6224–6266. https://doi.org/10.1039/C8CS00254A10.1039/C8CS00254A ↗
2. Novoselov KS, Geim AK, Morozov SV et al (2004) Electric field effect in atomically thin carbon films. Science 306:666–669. https://doi.org/10.1126/science.110289610.1126/science.1102896 ↗
3. Novoselov KS, Jing D, Schedin F, Booth TJ, Khotkevich VV, Morozov SV, Geim AK (2005) Two-dimensional atomic crystals. P Natl Acad Sci Usa 102:10451–10453. https://doi.org/10.1073/pnas.050284810210.1073/pnas.0502848102 ↗
4. Liu HY, Xi PX, Xie GQ et al (2012) Simultaneous reduction and surface functionalization of graphene oxide for hydroxyapatite mineralization. J Phys Chem C 116:3334–3341. https://doi.org/10.1021/jp210222610.1021/jp2102226 ↗
5. Yousefi N, Lu XL, Elimelech M, Tufenkji N (2019) Environmental performance of graphene-based 3D macrostructures. Nat Nanotechnol 14:107–119. https://doi.org/10.1038/s41565-018-0325-610.1038/s41565-018-0325-6 ↗
6. Zhang Y, Nayak TR, Hong H, Cai WB (2012) Graphene: a versatile nanoplatform for biomedical applications. Nanoscale 4:3833–3842. https://doi.org/10.1039/c2nr31040f10.1039/c2nr31040f ↗
7. Chen Y, Yang GZ, Liu B, Kong H, Xiong Z, Guo L, Wei G (2022) Biomineralization of ZrO2 nanoparticles on graphene oxide-supported peptide/cellulose binary nanofibrous membranes for high-performance removal of fluoride ions. Chem Eng J 430:132721–132731. https://doi.org/10.1016/j.cej.2021.13272110.1016/j.cej.2021.132721 ↗
8. Liu B, Jiang M, Zhu DZ, Zhang JM, Wei G (2022) Metal-organic frameworks functionalized with nucleic acids and amino acids for structure- and function-specific applications: a tutorial review. Chem Eng J 428:131118–131135. https://doi.org/10.1016/j.cej.2021.13111810.1016/j.cej.2021.131118 ↗
9. Palmieri V, Papi M (2020) Can graphene take part in the fight against COVID-19? Nano Today 33:100883–100886. https://doi.org/10.1016/j.nantod.2020.10088310.1016/j.nantod.2020.100883 ↗
10. Olabi AG, Abdelkareem MA, Wilberforce T, Sayed ET (2021) Application of graphene in energy storage device - a review. Renew Sust Energ Rev 135:110026–110045. https://doi.org/10.1016/j.rser.2020.11002610.1016/j.rser.2020.110026 ↗
11. Fan FR, Wang RX, Zhang H, Wu WZ (2021) Emerging beyond-graphene elemental 2D materials for energy and catalysis applications. Chem Soc Rev 50:10983–11031. https://doi.org/10.1039/C9CS00821G10.1039/C9CS00821G ↗
12. Zheng W, Liu XH, Xie JY, Lu GC, Zhang J (2021) Emerging van der Waals junctions based on TMDs materials for advanced gas sensors. Coordin Chem Rev 447:214151. https://doi.org/10.1016/j.ccr.2021.21415110.1016/j.ccr.2021.214151 ↗
13. Lin YX, Yu MX, Li XY et al (2021) Designed borophene/TMDs hybrid catalysts for enhanced hydrogen evolution reaction. J Mater Chem C. https://doi.org/10.1039/D1TC04197E10.1039/D1TC04197E ↗
14. Hassan J, Naz S, Haider A et al (2021) h-BN nanosheets doped with transition metals for environmental remediation; a DFT approach and molecular docking analysis. Mater Sci Eng B-Adv 272:115365–115378. https://doi.org/10.1016/j.mseb.2021.11536510.1016/j.mseb.2021.115365 ↗
15. Yanar H, Purcek G, Demirtas M, Ayar HH (2022) Effect of hexagonal boron nitride (h-BN) addition on friction behavior of low-steel composite brake pad material for railway applications. Tribol Int 165:107274–107288. https://doi.org/10.1016/j.triboint.2021.10727410.1016/j.triboint.2021.107274 ↗
16. Herrera-Reinoza N, Santos ACD, Lima LHD, Landers R, Siervo AD (2021) Atomically precise bottom-up synthesis of h-BNC: graphene doped with h-BN nanoclusters. Chem Mater 33:2871–2882. https://doi.org/10.1021/acs.chemmater.1c0008110.1021/acs.chemmater.1c00081 ↗
17. Lee W, Liu Y, Lee YJ et al (2018) Two-dimensional materials in functional three-dimensional architectures with applications in photodetection and imaging. Nat Commum 9:1417–1425. https://doi.org/10.1038/s41467-018-03870-010.1038/s41467-018-03870-0 ↗
18. Salazar N, Marquez C, Gamiz F (2021) Synthesis of graphene and other two-dimensional materials. Mater Nanophotonics 2D:1–79. https://doi.org/10.1016/B978-0-12-818658-9.00006-510.1016/B978-0-12-818658-9.00006-5 ↗
19. Zhao JL, Ma DT, Wang C et al (2021) Recent advances in anisotropic two-dimensional materials and device applications. Nano Res 14:897–919. https://doi.org/10.1007/s12274-020-3018-z10.1007/s12274-020-3018-z ↗
20. Danielson E, Sontakke VA, Porkovich AJ et al (2020) Graphene based field-effect transistor biosensors functionalized using gas-phase synthesized gold nanoparticles. Sensor Actuat B-Chem 320:128432–128438. https://doi.org/10.1016/j.snb.2020.12843210.1016/j.snb.2020.128432 ↗
21. Hilder TA, Gordon D, Chung SH (2009) Boron nitride nanotubes selectively permeable to cations or anions. Small 5:2870–2875. https://doi.org/10.1002/smll.20090122910.1002/smll.200901229 ↗
22. Deng LJ, Xu YF, Sun CX, Yun BF, Sun Q, Zhao CJ, Li Z (2018) Functionalization of small black phosphorus nanoparticles for targeted imaging and photothermal therapy of cancer. Sci Bull 63:917–924. https://doi.org/10.1016/j.scib.2018.05.02210.1016/j.scib.2018.05.022 ↗
23. Aizenberg J, Fratzl P (2009) Biological and biomimetic materials. Adv Mater 21:387–388. https://doi.org/10.1002/adma.20080369910.1002/adma.200803699 ↗
24. Calvert PD (1994) Polymers for new materials. Polymer 35:4484–4488. https://doi.org/10.1016/0032-3861(94)90792-710.1016/0032-3861(94)90792-7 ↗
25. Priyadarsini S, Mohanty S, Mukherjee S, Basu S, Mishra M (2018) Graphene and graphene oxide as nanomaterials for medicine and biology application. J Nanostruct Chem 8:123–137. https://doi.org/10.1007/s40097-018-0265-610.1007/s40097-018-0265-6 ↗
26. Antiochia R, Tortolini C, Tasca F, Gonton L, Bollella P (2018) Chapter 1-graphene and 2D-like nanomaterials: different biofunctionalization pathways for electrochemical biosensor development. Graphene Bioelectron 1–35. https://doi.org/10.1016/B978-0-12-813349-1.00001-910.1016/B978-0-12-813349-1.00001-9 ↗
27. Wei G, Gong CC, Hu KK, Wang YB, Zhang YT (2019) Biomimetic hydroxyapatite on graphene supports for biomedical applications: a review. Nanomaterials-Basel 9:1435–1454. https://doi.org/10.3390/nano910143510.3390/nano9101435 ↗
28. Nel AE, Mädler L, Velegol D et al (2009) Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater 8:543–557. https://doi.org/10.1038/nmat244210.1038/nmat2442 ↗
29. Geim AK (2009) Graphene: status and prospects. Science 324:1530–1534. https://doi.org/10.1126/science.115887710.1126/science.1158877 ↗
30. Meyer JC, Geim AK, Katsnelson ML, Novoselov KS, Booth TJ, Roth S (2007) The structure of suspended graphene sheets. Nature 446:60–63. https://doi.org/10.1038/nature0554510.1038/nature05545 ↗
31. Rao CNR, Sood AK, Subrahmanyam KS, Govindaraj A (2009) Graphene: the new two-dimensional nanomaterial. Angew Chem Int Edit 48:7752–7777. https://doi.org/10.1002/anie.20090167810.1002/anie.200901678 ↗
32. Yan L, Zheng YB, Zhao F et al (2012) Chemistry and physics of a single atomic layer: strategies and challenges for functionalization of graphene and graphene-based materials. Chem Soc Rev 41:97–114. https://doi.org/10.1039/c1cs15193b10.1039/c1cs15193b ↗
33. Sanchez VC, Jachak A, Hurt RH, Kane AB (2012) Biological interactions of graphene-family nanomaterials: an interdisciplinary review. Chem Res Toxicol 25:15–34. https://doi.org/10.1021/tx200339h10.1021/tx200339h ↗
34. Wang Y, Li ZH, Wang J, Li JH, Lin YH (2011) Graphene and graphene oxide: biofunctionalization and applications in biotechnology. Trends Biotechnol 29:205–212. https://doi.org/10.1016/j.tibtech.2011.01.00810.1016/j.tibtech.2011.01.008 ↗
35. Wang YQ, Sauriat-Dorizon H, Korri-Youssoufi H (2017) Direct electrochemical DNA biosensor based on reduced graphene oxide and metalloporphyrin nanocomposite. Sensor Actuat B-Chem 251:40–48. https://doi.org/10.1016/j.snb.2017.04.12810.1016/j.snb.2017.04.128 ↗
36. Bonanni A, Ambrosi A, Pumera M (2012) Nucleic acid functionalized graphene for biosensing. Chem-Eur J 18:1668–1673. https://doi.org/10.1002/chem.20110285010.1002/chem.201102850 ↗
37. Dubuisson E, Yang ZY, Loh KP (2011) Optimizing label-free DNA electrical detection on graphene platform. Anal Chem 83:2452–2460. https://doi.org/10.1021/ac102431d10.1021/ac102431d ↗
38. Lopez A, Liu J (2020) Covalent and noncovalent functionalization of graphene oxide with DNA for smart sensing. Adv Intell Syst 2:2000123–2000135. https://doi.org/10.1002/aisy.20200012310.1002/aisy.202000123 ↗
39. Husale BS, Sahoo S, Radenovic A, Traversi F, Annibale P, Kis A (2010) ssDNA binding reveals the atomic structure of graphene. Langmuir 26:18078–18082. https://doi.org/10.1021/la102518t10.1021/la102518t ↗
40. Moore TC, Yang AH, Ogungbesan O, Hartkamp R, Iacovella CR, Zhang Q, McCabe C (2019) Influence of single-stranded DNA coatings on the interaction between graphene nanoflakes and lipid bilayers. J Phys Chem B 123:7711–7721. https://doi.org/10.1021/acs.jpcb.9b0404210.1021/acs.jpcb.9b04042 ↗
41. Chen JL, Chen L, Wang Y, Chen SD (2014) Molecular dynamics simulations of the adsorption of DNA segments onto graphene oxide. J Phys D Appl Phys 47:505401–505406. https://doi.org/10.1088/0022-3727/47/50/50540110.1088/0022-3727/47/50/505401 ↗
42. Muraru S, Samoila CG, Slusanschi EI, Burns JS, Ionita M (2020) Molecular dynamics simulations of DNA adsorption on graphene oxide and reduced graphene oxide-PEG-NH2 in the Presence of Mg2+ and Cl- ions. Coatings 10:289–307. https://doi.org/10.3390/coatings1003028910.3390/coatings10030289 ↗
43. Xu Z, Lei XL, Tu YS, Tan ZJ, Song B, Fang HP (2017) Dynamic cooperation of hydrogen binding and π stacking in ssDNA adsorption on graphene oxide. Chem Eur J 23:13100–13104. https://doi.org/10.1002/chem.20170173310.1002/chem.201701733 ↗
44. Mahmoudi M, Lynch I, Ejtehadi MR, Monopoli MP, Bombelli FB, Laurent S (2011) Protein−nanoparticle interactions: opportunities and challenges. Chem Rev 111:5610–5637. https://doi.org/10.1021/cr100440g10.1021/cr100440g ↗
45. Li D, Zhang W, Yu X, Wang Z, Su Z, Wei G (2016) When biomolecules meet graphene: from molecular level interactions to material design and applications. Nanoscale 8:19491–19509. https://doi.org/10.1039/c6nr07249f10.1039/c6nr07249f ↗
46. Hampitak P, Melendrez D, Iliut M et al (2020) Protein interactions and conformations on graphene-based materials mapped using a quartz-crystal microbalance with dissipation monitoring (QCM-D). Carbon 165:317–327. https://doi.org/10.1016/j.carbon.2020.04.09310.1016/j.carbon.2020.04.093 ↗
47. Wang YQ, Zhu ZH, Zhang HM, Chen J, Tang BP, Cao J (2016) Investigation on the conformational structure of hemoglobin on graphene oxide. Mater Chem Phys 182:272–279. https://doi.org/10.1016/j.matchemphys.2016.07.03210.1016/j.matchemphys.2016.07.032 ↗
48. Kim KS, Um YM, Jang JR, Choe WS, Yoo PJ (2013) Highly sensitive reduced graphene oxide impedance sensor harnessing pi-stacking interaction mediated direct deposition of protein probes. ACS Appl Mater Inter 5:3591–3598. https://doi.org/10.1021/am303238r10.1021/am303238r ↗
49. Qian YH, Di SH, Wang L, Li Z (2021) Recent advance in the synthesis and applications of graphene-polypeptide nanocomposites. J Mater Chem B 9:6521–6535. https://doi.org/10.1039/D1TB00779C10.1039/D1TB00779C ↗
50. Wang L, Zhang YJ, Wu AG, Wei G (2017) Designed graphene-peptide nanocomposites for biosensor applications: a review. Anal Chim Acta 985:24–40. https://doi.org/10.1016/j.aca.2017.06.05410.1016/j.aca.2017.06.054 ↗
51. Yang ZX, Ge CC, Liu JJ et al (2015) Destruction of amyloid fibrils by graphene through penetration and extraction of peptides. Nanoscale 7:18725–18737. https://doi.org/10.1039/c5nr01172h10.1039/c5nr01172h ↗
52. Zou XQ, Wei S, Jasensky J, Xiao MY, Wang QM, Brooks CL, Chen Z (2017) Molecular interactions between graphene and biological molecules. J Am Chem Soc 139:1928–1936. https://doi.org/10.1021/jacs.6b1122610.1021/jacs.6b11226 ↗
53. Cheng Y, Zhang ZQ, Teo ZS (2013) Deformation of graphene induced by adsorption of peptides: A molecular dynamics study. Int Jappl Mech 05:1350007–1350017. https://doi.org/10.1142/s175882511350007510.1142/s1758825113500075 ↗
54. Kim S, Kuang ZF, Ngo Y, Farmer B, Naik RR (2015) Biotic-abiotic interactions: factors that influence peptide-graphene interactions. ACS Appl Mater Inter 7:20447–20453. https://doi.org/10.1021/acsami.5b0643410.1021/acsami.5b06434 ↗
55. Jin LL, Yang K, Yao K et al (2012) Functionalized graphene oxide in enzyme engineering: a selective modulator for enzyme activity and thermostability. ACS Nano 6:4864–4875. https://doi.org/10.1021/nn300217z10.1021/nn300217z ↗
56. Liu B, Wang Y, Chen Y, Guo L, Wei G (2020) Biomimetic two-dimensional nanozymes: synthesis, hybridization, functional tailoring, and biosensor applications. J Mater Chem B 8:10065–10086. https://doi.org/10.1039/D0TB02051F10.1039/D0TB02051F ↗
57. Zhang Y, Zhang JY, Huang XL, Zhou XJ, Wu HX, Guo SW (2012) Assembly of graphene oxide-enzyme conjugates through hydrophobic interaction. Small 8:154–159. https://doi.org/10.1002/smll.20110169510.1002/smll.201101695 ↗
58. Sun XT, Feng ZW, Hou TJ, Li YY (2014) Mechanism of graphene oxide as an enzyme inhibitor from molecular dynamics simulations. ACS Appl Mater Inter 6:7153–7163. https://doi.org/10.1021/am500167c10.1021/am500167c ↗
59. Zhang JL, Zhang F, Yang HJ, Huang XL, Liu H, Zhang JY, Guo SW (2010) Graphene oxide as a matrix for enzyme immobilization. Langmuir 26:6083–6085. https://doi.org/10.1021/la904014z10.1021/la904014z ↗
60. Radisavljevic B, Radenovic A, Brivio J, Giacometti V, Kis A (2011) Single-layer MoS2 transistors. Nat Nanotechnol 6:147–150. https://doi.org/10.1038/nnano.2010.27910.1038/nnano.2010.279 ↗
61. Zhou KQ, Jiang SH, Bao CL et al (2012) Preparation of poly(vinyl alcohol) nanocomposites with molybdenum disulfide (MoS2): structural characteristics and markedly enhanced properties. RSC Adv 2:11695–11703. https://doi.org/10.1039/c2ra21719h10.1039/c2ra21719h ↗
62. Xi Q, Zhou DM, Kan YY, Ge J, Wu ZK, Yu RQ, Jiang JH (2014) Highly sensitive and selective strategy for microRNA detection based on WS2 nanosheet mediated fluorescence quenching and duplex-specific nuclease signal amplification. Anal Chem 86:1361–1365. https://doi.org/10.1021/ac403944c10.1021/ac403944c ↗
63. Lu C, Liu YB, Ying YB, Liu JW (2017) Comparison of MoS2, WS2, and graphene oxide for DNA adsorption and sensing. Langmuir 33:630–637. https://doi.org/10.1021/acs.langmuir.6b0450210.1021/acs.langmuir.6b04502 ↗
64. Zhu CF, Zeng ZY, Li H, Li F, Fan CH, Zhang H (2013) Single-layer MoS2-based nanoprobes for homogeneous detection of biomolecules. J Am Chem Soc 135:5998–6001. https://doi.org/10.1021/ja401957210.1021/ja4019572 ↗
65. Li BL, Zou HL, Lu L, Yang Y, Lei JL, Luo HQ, Li NB (2015) Size-dependent optical absorption of layered MoS2 and DNA oligonucleotides induced dispersion behavior for label-free detection of single-nucleotide polymorphism. Adv Funct Mater 25:3541–3550. https://doi.org/10.1002/adfm.20150018010.1002/adfm.201500180 ↗
66. Liu F, Zhang YJ, Wang HB, Li LH, Zhao WJ, Shen JW, Liang LJ (2020) Study on the adsorption orientation of DNA on two-dimensional MoS2 surface via molecular dynamics simulation: a vertical orientation phenomenon. Chem Phys 529:110546–110552. https://doi.org/10.1016/j.chemphys.2019.11054610.1016/j.chemphys.2019.110546 ↗
67. Li AX, Zhang J, Qiu JC, Zhao ZH, Wang C, Zhao CJ, Liu H (2017) A novel aptameric biosensor based on the self-assembled DNA-WS2 nanosheet architecture. Talanta 163:78–84. https://doi.org/10.1016/j.Talanta.2016.10.08810.1016/j.Talanta.2016.10.088 ↗
68. Yang JM, Gao L, Peng C, Zhang W (2019) Construction of self-signal DNA electrochemical biosensor employing WS2 nanosheets combined with PIn6COOH. RSC Adv 9:9613–9619. https://doi.org/10.1039/c8ra10266j10.1039/c8ra10266j ↗
69. Wang ST, Zhang YL, Ning Y, Zhang GJ (2015) A WS2 nanosheet-based platform for fluorescent DNA detection via PNA-DNA hybridization. Analyst 140:434–439. https://doi.org/10.1039/c4an01738b10.1039/c4an01738b ↗
70. Fan HJ, Zhao DH, Li YT, Zhou J (2017) Lysozyme orientation and conformation on MoS2 surface: insights from molecular simulations. Biointerphases 12:02D416-1–02D416-8. https://doi.org/10.1116/1.498480310.1116/1.4984803 ↗
71. Gu ZL, Yang ZX, Kang SG, Yang JR, Luo JD, Zhou RH (2016) Robust denaturation of Villin Headpiece by MoS2 nanosheet: potential molecular origin of the nanotoxicity. Sci Rep-UK 6:28252–28259. https://doi.org/10.1038/srep2825210.1038/srep28252 ↗
72. Song J, Li MG, Liang HM, Lou H (2017) Adsorption patterns of aromatic amino acids on monolayer MoS2 and Au-modified MoS2 surfaces: a first-principles study. Comput Theor Chem 1118:115–122. https://doi.org/10.1016/j.comptc.2017.09.00510.1016/j.comptc.2017.09.005 ↗
73. Meng YJ, Liu RR, Zhu M, Zhai HL, Ren CL (2020) Exploring the interactions between flawed materials and YAP65 to reveal the role of vacancy defects in MoS2 sheet nanotoxicity. J Nanopart Res 22:208–218. https://doi.org/10.1007/s11051-020-04945-010.1007/s11051-020-04945-0 ↗
74. Gu ZL, Li WF, Hong LB, Zhou RH (2016) Exploring biological effects of MoS2 nanosheets on native structures of alpha-helical peptides. J Chem Phys 144:175103–175111. https://doi.org/10.1063/1.494845910.1063/1.4948459 ↗
75. Chen H, Li LB, Zhang T, Qiao ZW, Tang JH, Zhou J (2018) Protein translocation through a MoS2 nanopore: a molecular dynamics study. J Phys Chem C 122:2070–2080. https://doi.org/10.1021/acs.jpcc.7b0784210.1021/acs.jpcc.7b07842 ↗
76. Li X, Li YQ, Qiu Q et al (2019) Efficient biofunctionalization of MoS2 nanosheets with peptides as intracellular fluorescent biosensor for sensitive detection of caspase-3 activity. J Colloid Interf Sci 543:96–105. https://doi.org/10.1016/j.jcis.2019.02.01110.1016/j.jcis.2019.02.011 ↗
77. Mudedla SK, Murugan NA, Agren H (2018) Free energy landscape for alpha-helix to beta-sheet interconversion in small amyloid forming peptide under nanoconfinement. J Phys Chem B 122:9654–9664. https://doi.org/10.1021/acs.jpcb.8b0791710.1021/acs.jpcb.8b07917 ↗
78. Golberg D, Bando Y, Huang Y, Terao T, Mitome M, Tang CC, Zhi CY (2010) Boron nitride nanotubes and nanosheets. ACS Nano 4:2979–2993. https://doi.org/10.1021/nn100649510.1021/nn1006495 ↗
79. Weng QH, Wang XB, Wang X, Bando Y, Golberg D (2016) Functionalized hexagonal boron nitride nanomaterials: emerging properties and applications. Chem Soc Rev 45:3989–4012. https://doi.org/10.1039/c5cs00869g10.1039/c5cs00869g ↗
80. Magdalena JS, Martyna T, Mateusz D, Katarzyna P, Ewa M (2018) Hexagonal boron nitride functionalized with Au nanoparticles-properties and potential biological applications. Nanomater-Basel 8:605–626. https://doi.org/10.3390/nano808060510.3390/nano8080605 ↗
81. Chopra NG, Luyken RJ, Cherrey K, Crespi VH, Cohen ML, Louie SG, Zettl A (1995) Boron nitride nanotubes. Science 269:966–967. https://doi.org/10.1126/science.269.5226.96610.1126/science.269.5226.966 ↗
82. Wang JS, Lee CH, Yap YK (2010) Recent advancements in boron nitride nanotubes. Nanoscale 2:2028–2034. https://doi.org/10.1039/c0nr00335b10.1039/c0nr00335b ↗
83. Lin Q, Zou XL, Zhou G, Liu R, Wu J, Li J, Duan WH (2011) Adsorption of DNA/RNA nucleobases on hexagonal boron nitride sheet: an ab initio study. Phys Chem Chem Phys 13:12225–12230. https://doi.org/10.1039/c1cp20783k10.1039/c1cp20783k ↗
84. Lee JH, Choi YK, Kim HJ, Scheicher RH, Cho JH (2013) Physisorption of DNA nucleobases on h-BN and graphene: vdW-corrected DFT calculations. J Phys Chem C 117:13435–13441. https://doi.org/10.1021/jp402403f10.1021/jp402403f ↗
85. Zhang LY, Wang XQ (2016) DNA sequencing by hexagonal boron nitride nanopore: a computational study. Nanomater-Basel 6:111–121. https://doi.org/10.3390/nano606011110.3390/nano6060111 ↗
86. Lu T, Wang LB, Jiang Y, Liu QW, Huang CJ (2016) Hexagonal boron nitride nanoplates as emerging biological nanovectors and their potential applications in biomedicine. J Mater Chem B 4:6103–6110. https://doi.org/10.1039/c6tb01481j10.1039/c6tb01481j ↗
87. Lin Y, Williams TV, Xu TB, Cao W, Elsayed-Ali HE, Connell JW (2011) Aqueous dispersions of few-layered and monolayered hexagonal boron nitride nanosheets from sonication-assisted hydrolysis:critical role of water. J Phys Chem C 115:2679–2685. https://doi.org/10.1021/jp110985w10.1021/jp110985w ↗
88. Guan M, Hao L, Chen L et al (2020) Facile mechanical-induced functionalization of hexagonal boron nitride and its application as vehicles for antibacterial essential oil. ACS Sustain Chem Eng 8:15120–15133. https://doi.org/10.1021/acssuschemeng.0c0378110.1021/acssuschemeng.0c03781 ↗
89. Mudedla SK, Balamurugan K, Subramanian V (2016) Unravelling the structural changes in α-helical peptides on interaction with convex, concave and planar surfaces of boron nitride based nanomaterials. J Phys Chem C 120:28246–28260. https://doi.org/10.1021/acs.jpcc.6b0858710.1021/acs.jpcc.6b08587 ↗
90. Zhang HJ, Yamazaki T, Zhi CY, Hanagata N (2012) Identification of a boron nitride nanosphere-binding peptide for the intracellular delivery of CpG oligodeoxynucleotides. Nanoscale 4:6343–6350. https://doi.org/10.1039/c2nr31189e10.1039/c2nr31189e ↗
91. Brljak N, Parab AD, Rao R, Slocik JM, Naik RR, Knecht MR, Walsh TR (2020) Material composition and peptide sequence affects biomolecule affinity to and selectivity for h-boron nitride and graphene. Chem Commun 56:8834–8837. https://doi.org/10.1039/D0CC02635B10.1039/D0CC02635B ↗
92. Shi L, Mu CL, Gao T et al (2019) Rhodopsin-like ionic gate fabricated with graphene oxide and isomeric DNA switch for efficient photocontrol of ion transport. J Am Chem Soc 141:8239–8243. https://doi.org/10.1021/jacs.9b0175910.1021/jacs.9b01759 ↗
93. Liu SK, Mou S, Zhou CC et al (2018) Off-the-shelf biomimetic graphene oxide-collagen hybrid scaffolds wrapped with osteoinductive extracellular matrix for the repair of cranial defects in rats. ACS Appl Mater Inter 10:42948–42958. https://doi.org/10.1021/acsami.8b1107110.1021/acsami.8b11071 ↗
94. Jiao D, Zheng A, Liu Y et al (2021) Bidirectional differentiation of BMSCs induced by a biomimetic procallus based on a gelatin-reduced graphene oxide reinforced hydrogel for rapid bone regeneration. Bioact Mater 6:2011–2028. https://doi.org/10.1016/j.bioactmat.2020.12.00310.1016/j.bioactmat.2020.12.003 ↗
95. Kim JY, Kim HD, Park J et al (2018) Enhanced osteogenic commitment of murine mesenchymal stem cells on graphene oxide substrate. Biomaterials 22:1–9. https://doi.org/10.1186/s40824-017-0112-810.1186/s40824-017-0112-8 ↗
96. Guo CX, Ng SR, Khoo SY, Zheng XT, Chen P, Li CM (2012) RGD-peptide functionalized graphene biomimetic live-cell sensorfor real-time detection of nitric oxide molecules. ACS Nano 6:6944–6951. https://doi.org/10.1021/nn301974u10.1021/nn301974u ↗
97. Xia JJ, Wang PY, Bin Z, Onyinye AI (2021) Enhancing electrochemical sensing for catechol by biomimetic oxidase covalently functionalized graphene oxide. Bioproc Biosyst Eng 44:343–353. https://doi.org/10.1007/s00449-020-02446-x10.1007/s00449-020-02446-x ↗
98. Wang LM, Lin XY, Wang J et al (2014) Novel insights into combating cancer chemotherapy resistance using a plasmonic nanocarrier: enhancing drug sensitiveness and accumulation simultaneously with localized mild photothermal stimulus of femtosecond pulsed laser. Adv Funct Mater 24:4229–4239. https://doi.org/10.1002/adfm.20140001510.1002/adfm.201400015 ↗
99. Li LL, Tang FQ, Liu HY et al (2011) In vivo delivery of silica nanorattle encapsulated docetaxel for liver cancer therapy with low toxicity and high efficacy. ACS Nano 5:6874–6882. https://doi.org/10.1021/nn103380r10.1021/nn100918a ↗
100. Xie M, Yang M, Sun X, Yang N, Deng TT, Li YP, Shen HJ (2020) WS2 nanosheets functionalized by biomimetic lipids with enhanced dispersibility for photothermal and chemo combination therapy. J Mater Chem B 8:2331–2342. https://doi.org/10.1039/c9tb01604j10.1039/c9tb01604j ↗