Fabrication of bimetallic ZIF/carbon nanofibers composite for electrochemical sensing of adrenaline
Source abstract
Abstract
The detection method with potential ability to diagnose drugs in human serum rapidly, highly sensitivity and selectivity is of vital importance for clinical diagnosis. In this paper, an electrochemical sensor on the basis of composite material modified by zeolitic imidazolate framework (ZIF) on carbon nanofiber (CNF) surface is constructed, which is used for ultra-sensitive determination of adrenaline (AD). CoMnZIF-CNF combines the good conductivity of carbon nanofibers and the high electrocatalysis of CoMnZIF, which can improve the reaction activity and the sensing effect of adrenaline. The proposed sensor shows a good linear relationship between AD concentration from 5 to 1000 μM, and the detection limit is 0.22 μM. Meanwhile, CoMnZIF-CNF demonstrated the remarkable selectivity, significant repeatability and stability, as well as excellent reproducibility. Besides, through the analysis of AD in serum electrolyte, the practicability of the sensor was evaluated and the recovery rate was between 97.51 and 102.53%. On the basis of the results, the prepared sensor has a vital application prospect in detecting AD in actual sample analysis.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Electrochemical sensors and biosensors · Conducting polymers and applications · Advanced biosensing and bioanalysis techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (37)
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