A viewpoint on material and design considerations for oesophageal stents with extended lifetime
Source abstract
Abstract
Abstract Oesophageal stents are meshed tubular implants designed to maintain patency of the oesophageal lumen and attenuate the symptoms of oesophageal cancer. Oesophageal cancers account for one in twenty cancer diagnoses and can lead to dysphasia, malnutrition and the diminishment of patient quality of life (QOL). Self-expanding oesophageal stents are the most common approach to attenuate these symptoms. Recent advances in oncological therapy have enabled patient survival beyond the lifetime of current devices. This introduces new complications for palliation, driving the need for innovation in stent design. This review identifies the factors responsible for stent failure. It explores the challenges of enhancing the longevity of stent therapies and outlines solutions to improving clinical outcomes. Discussions focus on the role of stent materials, construction methods, and coatings upon device performance. We found three key stent enhancement strategies currently used; material surface treatments, anti-migratory modifications, and biodegradable skeletons. Furthermore, radioactive and drug eluting stent designs were identified as emerging novel treatments. In conclusion, the review offers an overview of remaining key challenges in oesophageal stent design and potential solutions. It is clear that further research is needed to improve the clinical outcome of stents and patient QOL.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Esophageal and GI Pathology · Tracheal and airway disorders · Esophageal Cancer Research and Treatment
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Black S, Edwards D, Smith G, Laasch H-U (2018) Gastrointestinal stents: materials and designs. Dig Dis Interv 02:003–010. https://doi.org/10.1055/s-0038-163961310.1055/s-0038-1639613 ↗
2. Kaltsidis H, Mansoor W, Park JH et al (2018) Oesophageal stenting: status quo and future challenges. Br J Radiol. https://doi.org/10.1259/bjr.2017093510.1259/bjr.20170935 ↗
3. Bray F, Ferlay J, Soerjomataram I et al (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. https://doi.org/10.3322/caac.2149210.3322/caac.21492 ↗
4. Homs MYV, Siersema PD (2012) Chapter 28: Endoscopic Palliation of Malignant Dysphagia and Esophageal Fistulas. In: Ginsberg GG, Gostout CJ, Kochman ML, Norton ID (Eds) Clinical gastrointestinal endoscopy, 2nd edn, pp 350–372. https://doi.org/10.1016/B978-1-4377-1529-3.00028-210.1016/B978-1-4377-1529-3.00028-2 ↗
5. Dai Y, Li C, Xie Y et al (2014) Interventions for dysphagia in oesophageal cancer. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD005048.pub410.1002/14651858.CD005048.pub4 ↗
6. Tan BHL, Brammer K, Randhawa N et al (2015) Sarcopenia is associated with toxicity in patients undergoing neo-adjuvant chemotherapy for oesophago-gastric cancer. Eur J Surg Oncol 41:333–338. https://doi.org/10.1016/j.ejso.2014.11.04010.1016/j.ejso.2014.11.040 ↗
7. Berry MF (2014) Esophageal cancer: staging system and guidelines for staging and treatment. J Thorac Dis 6(Suppl 3):S289–S297. https://doi.org/10.3978/j.issn.2072-1439.2014.03.1110.3978/j.issn.2072-1439.2014.03.11 ↗
8. Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A (2010) Lip and Oral Cavity. AJCC Cancer Staging Manual, 7th edn. Springer, Chicago, pp 33–34
9. Rice TW, Rusch VW, Ishwaran H, Blackstone EH (2010) Cancer of the esophagus and esophagogastric junction. Cancer 116:3763–3773. https://doi.org/10.1002/cncr.2514610.1002/cncr.25146 ↗
10. Demeester TR (1997) Esophageal carcinoma: current controversies. Semin Surg Oncol 13:217–23310.1002/(SICI)1098-2388(199707/08)13:4<217::AID-SSU2>3.0.CO;2-8 ↗
11. Adler DG, Baron TH (2001) Endoscopic palliation of malignant dysphagia. Mayo Clin Proc 76:731–738. https://doi.org/10.4065/76.7.73110.4065/76.7.731 ↗
12. Weston A (2011) Stents in the proximal esophagus: tailoring the stent to the patient to achieve success. YMGE 73:1106–1108. https://doi.org/10.1016/j.gie.2011.02.01610.1016/j.gie.2011.02.016 ↗
13. D’Etoilles L (1845) De Lavacherie De l’Oesophagotomie. Bruxelles
14. Frimberger E (1983) Expanding spiral - a new type of prosthesis for the palliative treatment of malignant esophageal stenoses. Endoscopy 15:213–214. https://doi.org/10.1055/s-2007-102151110.1055/s-2007-1021511 ↗
15. Irani S, Kozarek RA (2013) Self-Expandable Stents in the Gastrointestinal Tract. In: Kozarek R, Baron T, Song H-Y (eds) Self-expandable stents in the gastrointestinal tract. Springer, New York, NY, New York, NY
16. Davids PHP, Groen AK, Rauws EAJ et al (1992) Randomised trial of self-expanding metal stents versus polyethylene stents for distal malignant biliary obstruction. Lancet 340:1488–1492. https://doi.org/10.1016/0140-6736(92)92752-210.1016/0140-6736(92)92752-2 ↗
17. De Palma GD, di Matteo E, Romano G et al (1996) Plastic prosthesis versus expandable metal stents for palliation of inoperable esophageal thoracic carcinoma: a controlled prospective study. Gastrointest Endosc 43:478–482. https://doi.org/10.1016/S0016-5107(96)70290-010.1016/S0016-5107(96)70290-0 ↗
18. Bona D, Laface L, Bonavina L et al (2010) Covered nitinol stents for the treatment of esophageal strictures and leaks. World J Gastroenterol 16:2260–2264. https://doi.org/10.3748/wjg.v16.i18.226010.3748/wjg.v16.i18.2260 ↗
19. Whiteoak SR, Frost R, Loehry J et al (2012) PWE-036 What is the survival of patients with oesophageal cancer following palliative stenting? Gut 61:A311.2-A311. https://doi.org/10.1136/gutjnl-2012-302514d.3610.1136/gutjnl-2012-302514d.36 ↗
20. van Boeckel PG, Siersema PD, Sturgess R et al (2010) A new partially covered metal stent for palliation of malignant dysphagia: a prospective follow-up study. Gastrointest Endosc 72:1269–1273. https://doi.org/10.1016/j.gie.2010.07.04010.1016/j.gie.2010.07.040 ↗
21. Laasch H, Lee S, Moss JG (2004) The British society of interventional radiology ROST - registry of oesophageal stenting first report 2004, First Repo. Henley-on-Thames: The British Institute of Radiology
22. Waddell T, Verheij M, Allum W et al (2013) Gastric cancer+: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. https://doi.org/10.1093/annonc/mdt34410.1093/annonc/mdt344 ↗
23. Bang YJ, Van Cutsem E, Feyereislova A et al (2010) Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial. Lancet 376:687–697. https://doi.org/10.1016/S0140-6736(10)61121-X10.1016/S0140-6736(10)61121-X ↗
24. Lunt CR, Najaran P, Edwards DE et al (2018) The vanishing stent: repeated fracture and dissolution of nitinol gastric stents in a long term cancer survivor. Gastrointest Interv 7:88–90. https://doi.org/10.18528/gii17001010.18528/gii170010 ↗
25. Khara HS, Diehl DL, Gross SA (2014) Esophageal stent fracture: case report and review of the literature. World J Gastroenterol 20:2715–2720. https://doi.org/10.3748/wjg.v20.i10.271510.3748/wjg.v20.i10.2715 ↗
26. Phillips-Hughes DJ (2010) Oesophageal Stents | BSIR. https://www.bsir.org/patients/oesophageal-stents/. Accessed 15 Oct 2021
27. Chen H, Shen W, Liu K (2017) Radioactive self-expanding stents for palliative management of unresectable esophageal cancer: a systematic review and meta-analysis. Dis Esophagus Off J Int Soc Dis Esophagus. https://doi.org/10.1093/DOTE/DOW01010.1093/DOTE/DOW010 ↗
28. Singh P, Singh A, Singh A et al (2016) Long term outcome in patients with esophageal stenting for cancer esophagus - our experience at a rural hospital of Punjab, India. J Clin Diagn Res. https://doi.org/10.7860/JCDR/2016/22950.899410.7860/JCDR/2016/22950.8994 ↗
29. Mushi BP, Mwachiro MM, Buckle G et al (2021) Improving access to self-expanding metal stents for patients with esophageal cancer in Eastern Africa: a stepwise implementation strategy. JCO Global Oncol 7:118–126. https://doi.org/10.1200/GO.20.0031810.1200/GO.20.00318 ↗
30. Hindy P, Hong J, Lam-Tsai Y, Gress F (2012) A comprehensive review of esophageal stents. Clin Adv Hematol Oncol 10:526–534
31. Martinez JC, Puc MM, Quiros RM (2011) Esophageal stenting in the setting of malignancy. ISRN Gastroenterol 2011:1–9. https://doi.org/10.5402/2011/71957510.5402/2011/719575 ↗
32. Schembre D (2010) Advances in esophageal stenting: the evolution of fully covered stents for malignant and benign disease. Adv Ther 27:413–425. https://doi.org/10.1007/s12325-010-0042-510.1007/s12325-010-0042-5 ↗
33. Kim KY, Tsauo J, Song H-Y et al (2017) Self-expandable metallic stent placement for the palliation of esophageal cancer. J Korean Med Sci 32:1062–1071. https://doi.org/10.3346/jkms.2017.32.7.106210.3346/jkms.2017.32.7.1062 ↗
34. Park DH, Lee SS, Lee TH et al (2011) Anchoring flap versus flared end, fully covered self-expandable metal stents to prevent migration in patients with benign biliary strictures: a multicenter, prospective, comparative pilot study (with videos). Gastrointest Endosc 73:64–70. https://doi.org/10.1016/j.gie.2010.09.03910.1016/j.gie.2010.09.039 ↗
35. Hussain Z, Diamantopoulos A, Krokidis M, Katsanos K (2016) Double-layered covered stent for the treatment of malignant oesophageal obstructions: systematic review and meta-analysis. World J Gastroenterol 22:7841–7850. https://doi.org/10.3748/wjg.v22.i34.784110.3748/wjg.v22.i34.7841 ↗
36. Verschuur EML, Homs MYV, Steyerberg EW et al (2006) A new esophageal stent design (Niti-S stent) for the prevention of migration: a prospective study in 42 patients. Gastrointest Endosc. https://doi.org/10.1016/j.gie.2005.07.05110.1016/j.gie.2005.07.051 ↗
37. Vermeulen BD, Reijm AN, van der Bogt RD et al (2019) Sa1285 Though-the-scope placement of a new fully covered metal esophageal stent for palliation of malignant dysphagia: a prospective feasibility study. Gastrointest Endosc 89:205. https://doi.org/10.1016/j.gie.2019.03.17510.1016/j.gie.2019.03.175 ↗
38. Cusumano A, Ruol A, Segalin A et al (1992) Push-through intubation: Effective palliation in 409 patients with cancer of the esophagus and cardia. Ann Thorac Surg 53:1010–1014. https://doi.org/10.1016/0003-4975(92)90376-F10.1016/0003-4975(92)90376-F ↗
39. Mocanu A, Bârla R, Hoara P, Constantinoiu S (2015) Endoscopic palliation of advanced esophageal cancer. J Med Life 8:193–201
40. García-Cano J (2008) Dilation of benign strictures in the esophagus and colon with the polyflex stent: a case series study. Dig Dis Sci 53:341–346. https://doi.org/10.1007/s10620-007-9864-710.1007/s10620-007-9864-7 ↗
41. Costamagna G, Shah SK, Tringali A et al (2003) Prospective evaluation of a new self-expanding plastic stent for inoperable esophageal strictures. Surg Endosc Other Interv Tech 17:891–895. https://doi.org/10.1007/s00464-002-9098-x10.1007/s00464-002-9098-x ↗
42. Langer FB, Wenzl E, Prager G et al (2005) Management of postoperative esophageal leaks with the polyflex self-expanding covered plastic stent. Ann Thorac Surg 79:398–403. https://doi.org/10.1016/j.athoracsur.2004.07.00610.1016/j.athoracsur.2004.07.006 ↗
43. Holm AN, de la Mora Levy JG, Gostout CJ et al (2008) Self-expanding plastic stents in treatment of benign esophageal conditions. Gastrointest Endosc 67:20–25. https://doi.org/10.1016/j.gie.2007.04.03110.1016/j.gie.2007.04.031 ↗
44. Boston Scientific Corporation (2014) Polyflex Esophageal Stent
45. Tokar JL, Banerjee S, Barth BA et al (2011) Drug-eluting/biodegradable stents. Gastrointest Endosc 74:954–958. https://doi.org/10.1016/j.gie.2011.07.02810.1016/j.gie.2011.07.028 ↗
46. Sigounas D, Siddhi S, Plevris J (2016) Biodegradable esophageal stents in benign and malignant strictures – a single center experience. Endosc Int Open 04:E618–E623. https://doi.org/10.1055/s-0042-10543310.1055/s-0042-105433 ↗
47. Pereira-Lima JC, Ramires RP, Zamin I et al (1999) Endoscopic dilation of benign esophageal strictures: Report on 1043 procedures. Am J Gastroenterol 94:1497–1501. https://doi.org/10.1111/j.1572-0241.1999.01061.x10.1111/j.1572-0241.1999.01061.x ↗
48. ELLA-CS (2020) BD STENT
49. Irani S, Kozarek RA (2013) History of GI Stenting: Rigid Prostheses in the Esophagus. Self-expandable stents in the gastrointestinal tract. Springer, New York, New York, NY
50. May A, Hahn EG, Ell C (1996) Self-expanding metal stents for palliation of malignant obstruction in the upper gastrointestinal tract: comparative assessment of three stent types implemented in 96 implantations. J Clin Gastroenterol 22:261–266. https://doi.org/10.1097/00004836-199606000-0000410.1097/00004836-199606000-00004 ↗
51. Laasch HU, Marriott A, Wilbraham L et al (2002) Effectiveness of open versus antireflux stents for palliation of distal esophageal carcinoma and prevention of symptomatic gastroesophageal reflux. Radiology 225:359–365. https://doi.org/10.1148/radiol.225201176310.1148/radiol.2252011763 ↗
52. Ell C, May A, Hahn EG (1995) Gianturco-Z Stents in the palliative treatment of malignant esophageal obstruction and esophagotracheal fistulas. Endoscopy 27:495–500. https://doi.org/10.1055/s-2007-100575410.1055/s-2007-1005754 ↗
53. McDevitt JL, Goldman DT, Bundy JJ et al (2020) Gianturco z-stent placement for the treatment of chronic central venous occlusive disease: implantation of 208 stents in 137 symptomatic patients. Diagnostic Interv Radiol 27:72–78. https://doi.org/10.5152/dir.2020.1928210.5152/dir.2020.19282 ↗
54. Otsuka K, Ren X (2005) Physical metallurgy of Ti-Ni-based shape memory alloys. Prog Mater Sci 50:511–67810.1016/j.pmatsci.2004.10.001 ↗
55. Christian JW (2002) Chapter 26: Shape Memory Alloys. In: The Theory of Transformations in Metal and Alloys. Pergamom, pp 1102–111310.1016/B978-008044019-4/50031-3 ↗
56. Solomon JA, Stavropolous SW (2010) Equipment, terms, and techniques in interventional radiology. In: Radiology Secrets Plus: Third Edition. Mosby, pp 217–22210.1016/B978-0-323-06794-2.00029-8 ↗
57. Pandit A, Planell J, Navarro M (2013) Titanium and Nitinol (NiTi). In: Biomaterials Science: An Introduction to Materials: Third Edition. Elsevier Inc., pp 120–12410.1016/B978-0-08-087780-8.00014-0 ↗
58. Lemons JE, Misch-Dietsh F, McCracken MS (2014) Biomaterials for Dental Implants. In: Dental Implant Prosthetics. Elsevier Inc., pp 66–9410.1016/B978-0-323-07845-0.00004-X ↗
59. Brochu ABW, Craig SL, Reichert WM (2011) Self-healing biomaterials. J Biomed Mater Res - Part A 96A:492–506. https://doi.org/10.1002/jbm.a.3298710.1002/jbm.a.32987 ↗
60. Jenko M, Godec M, Kocijan A et al (2019) A new route to biocompatible Nitinol based on a rapid treatment with H2/O2 gaseous plasma. Appl Surf Sci 473:976–984. https://doi.org/10.1016/j.apsusc.2018.12.14010.1016/j.apsusc.2018.12.140 ↗
61. Thyssen JP, Johansen JD, Menné T et al (2010) Hypersensitivity reactions from metallic implants: a future challenge that needs to be addressed. Br J Dermatol 162:235–236. https://doi.org/10.1111/j.1365-2133.2009.09526.x10.1111/j.1365-2133.2009.09526.x ↗
62. Biesiekierski A, Wang J, Abdel-Hady Gepreel M, Wen C (2012) A new look at biomedical Ti-based shape memory alloys. Acta Biomater 8:1661–1669. https://doi.org/10.1016/j.actbio.2012.01.01810.1016/j.actbio.2012.01.018 ↗
63. Köster R, Vieluf D, Kiehn M et al (2000) Nickel and molybdenum contact allergies in patients with coronary in-stent restenosis. Lancet 356:1895–1897. https://doi.org/10.1016/S0140-6736(00)03262-110.1016/S0140-6736(00)03262-1 ↗
64. Mönkemüller K, Zimmermann L (2009) Self-Expanding Metallic Stents for the Palliation of Malignant Esophageal Obstruction. In: Mönkemüller K, Wilcox C, Muñoz-Navas M (eds) Interventional and Therapeutic Gastrointestinal Endoscopy. KARGER, Basel, pp 106–11410.1159/000258353 ↗
65. Goldin E, Beyar M, Safra T et al (1994) A new self-expandable, nickel-titanium coil stent for esophageal obstruction: a preliminary report. Gastrointest Endosc 40:64–68. https://doi.org/10.1016/S0016-5107(94)70012-510.1016/S0016-5107(94)70012-5 ↗
66. Naso P, Bonanno G, Aprile G et al (2001) EsophaCoil for palliation of dysphagia in unresectable oesophageal carcinoma: short- and long-term results. Dig Liver Dis 33:653–658. https://doi.org/10.1016/S1590-8658(01)80040-210.1016/S1590-8658(01)80040-2 ↗
67. Maetani I, Nambu T, Omuta S et al (2010) Treating bilio-duodenal obstruction: combining new endoscopic technique with 6 Fr stent introducer. World J Gastroenterol 16:2828–2831. https://doi.org/10.3748/wjg.v16.i22.282810.3748/wjg.v16.i22.2828 ↗
68. Yoshida H, Tajiri T, Mamada Y et al (2004) Fracture of a biliary expandable metallic stent. Gastrointest Endosc 60:655–658. https://doi.org/10.1016/S0016-5107(04)01884-X10.1016/S0016-5107(04)01884-X ↗
69. Ali MN, Busfield JJC, Rehman IU (2014) Auxetic oesophageal stents: structure and mechanical properties. J Mater Sci Mater Med 25:527–553. https://doi.org/10.1007/s10856-013-5067-210.1007/s10856-013-5067-2 ↗
70. Grima JN, Jackson R, Alderson A, Evans KE (2000) Do zeolites have negative poisson’s ratios? Adv Mater 12:1912–1918. https://doi.org/10.1002/1521-4095(200012)12:24%3c1912::AID-ADMA1912%3e3.0.CO;2-710.1002/1521-4095(200012)12:24<1912::AID-ADMA1912>3.0.CO;2-7 ↗
71. Laasch H-U, Edwards DW, Song H-Y (2016) Enteral stent construction: current principles. Gastrointest Interv 5:85–89. https://doi.org/10.18528/gii16000910.18528/gii160009 ↗
72. Kang S-G (2010) Gastrointestinal stent update. Gut Liver 4:S19. https://doi.org/10.5009/gnl.2010.4.S1.S1910.5009/gnl.2010.4.S1.S19 ↗
73. McHugo V (2014) Braided helical wire stent - US Patent 8, 875,372. Google Patents
74. Kang Y (2019) A review of self-expanding esophageal stents for the palliation therapy of inoperable esophageal malignancies. Biomed Res Int 2019:1–11. https://doi.org/10.1155/2019/926501710.1155/2019/9265017 ↗
75. Yakoub D, Ramy AE, Ae F et al (2008) Evidence-based choice of esophageal stent for the palliative management of malignant dysphagia. World J Surg 32:1996–2009. https://doi.org/10.1007/s00268-008-9654-110.1007/s00268-008-9654-1 ↗
76. Ramakrishnaiah VPN, Malage S, Sreenath GS et al (2016) Palliation of dysphagia in carcinoma esophagus. Clin Med Insights Gastroenterol 9:11–2310.4137/CGast.S30303 ↗
77. Meike C, Hirdes AM, Vleggaar FP, de Beule M et al (2013) In vitro evaluation of the radial and axial force of self-expanding esophageal stents. Endoscopy. https://doi.org/10.1055/s-0033-134498510.1055/s-0033-1344985 ↗
78. Eickhoff A, Knoll M, Jakobs R et al (2005) Self-expanding metal stents versus plastic prostheses in the palliation of malignant dysphagia: Long-term outcome of 153 consecutive patients. J Clin Gastroenterol 39:877–885. https://doi.org/10.1097/01.mcg.0000180631.61819.4a10.1097/01.mcg.0000180631.61819.4a ↗
79. Orive-Calzada A, Álvarez-Rubio M, Romero-Izquierdo S et al (2009) Severe epithelial hyperplasia as a complication of a novel biodegradable stent. Endoscopy 41:E137–E138. https://doi.org/10.1055/s-0029-121463410.1055/s-0029-1214634 ↗
80. Ramirez FC, Dennert B, Zierer ST, Sanowski RA (1997) Esophageal self-expandable metallic stents-indications, practice, techniques, and complications: Results of a national survey. Gastrointest Endosc 45:360–364. https://doi.org/10.1016/S0016-5107(97)70144-510.1016/S0016-5107(97)70144-5 ↗
81. Boston Scientific Corporation (2014) WallFlex
82. Franca DCC, de Castro AL, Soubhia AMP et al (2013) Evaluation of the biocompatibility of silicone gel implants-histomorphometric study. Acta Inform Medica 21:93–97. https://doi.org/10.5455/aim.2013.21.93-9710.5455/aim.2013.21.93-97 ↗
83. Sardar VB, Rajhans NR, Pathak A, Prabhu T (2016) Development in silicone material for biomedical applications. In: 14th International Conference on Humanizing Work and Work Environment HWWE-2016
84. Kim HB, Baik KY, Moon MH, Sung CK (2016) Enhanced Corrosion Resistance of Silicone-Coated Stents by Plasma Treatment. In: 5th International Science Congress & Exhibition. pp 857–86010.12693/APhysPolA.129.857 ↗
85. Maitz MF (2015) Applications of synthetic polymers in clinical medicine. Biosurface and Biotribology 1:161–176. https://doi.org/10.1016/j.bsbt.2015.08.00210.1016/j.bsbt.2015.08.002 ↗
86. Park JS, Jeong S, Lee DH (2015) Recent advances in gastrointestinal stent development. Clin Endosc 48:209–215. https://doi.org/10.5946/ce.2015.48.3.20910.5946/ce.2015.48.3.209 ↗
87. Mikhailov IV, Sidorchuk SV, Lavrusenko SR (2002) Polytetrafluoroethylene in medicine. Int Polym Sci Technol 29:38–41
88. Cardoso VF, Correia DM, Ribeiro C et al (2018) Fluorinated polymers as smart materials for advanced biomedical applications. Polymers (Basel). https://doi.org/10.3390/polym1002016110.3390/polym10020161 ↗
89. Ebnesajjad S (2017) Medical and Surgical Applications of Expanded PTFE. In: Expanded PTFE Applications Handbook. Elsevier, pp 193–21110.1016/B978-1-4377-7855-7.00009-2 ↗
90. Ebnesajjad S (2017) Properties, Characteristics, and Applications of Expanded PTFE (ePTFE) Products. In: Expanded PTFE Applications Handbook. Elsevier, pp 163–17010.1016/B978-1-4377-7855-7.00007-9 ↗
91. Vera ML, Rosenberger MR, Schvezov CE, Ares AE (2015) Fabrication of TiO2 crystalline coatings by combining Ti-6Al-4V anodic oxidation and heat treatments. Int J Biomater. https://doi.org/10.1155/2015/39565710.1155/2015/395657 ↗
92. Regonini D, Jaroenworaluck A, Stevens R, Bowen CR (2010) Effect of heat treatment on the properties and structure of TiO 2 nanotubes: phase composition and chemical composition. Surface Interface Anal. https://doi.org/10.1002/sia.318310.1002/sia.3183 ↗
93. Lu T, Qiao Y, Liu X (2012) Surface modification of biomaterials using plasma immersion ion implantation and deposition. Interface Focus. https://doi.org/10.1098/rsfs.2012.000310.1098/rsfs.2012.0003 ↗
94. Wang G, Li J, Lv K et al (2016) Surface thermal oxidation on titanium implants to enhance osteogenic activity and in vivo osseointegration. Nat Publ Gr. https://doi.org/10.1038/srep3176910.1038/srep31769 ↗
95. Cigada A, Cabrini M, Pedeferri P (1992) Increasing of the corrosion resistance of the Ti6Al4V alloy by high thickness anodic oxidation. J Mater Sci Mater Med 3:408–412. https://doi.org/10.1007/BF0070123610.1007/BF00701236 ↗
96. Vera ML, Alterach MÁ, Rosenberger MR et al (2014) Characterization of TiO 2nanofilms obtained by sol-gel and anodic oxidation. Nanomater Nanotechnol 4:10. https://doi.org/10.5772/5852210.5772/58522 ↗
97. Armitage DA, Grant DM (2003) Characterisation of surface-modified nickel titanium alloys. Mater Sci Eng A 349:89–97. https://doi.org/10.1016/S0921-5093(02)00818-310.1016/S0921-5093(02)00818-3 ↗
98. Liu X, Chu PK, Ding C (2004) Surface modification of titanium, titanium alloys, and related materials for biomedical applications. Mater Sci Eng R Reports 47:49–121. https://doi.org/10.1016/j.mser.2004.11.00110.1016/j.mser.2004.11.001 ↗
99. Anders A (1997) Metal plasma immersion ion implantation and deposition: a review. Surf Coatings Technol. https://doi.org/10.1016/S0257-8972(97)00037-610.1016/S0257-8972(97)00037-6 ↗
100. Pohl M, Glogowski T, Kühn S et al (2008) Formation of titanium oxide coatings on NiTi shape memory alloys by selective oxidation. Mater Sci Eng A 481:123–126. https://doi.org/10.1016/j.msea.2007.02.15110.1016/j.msea.2007.02.151 ↗