Effects of scandium addition on the in vitro degradation behavior of biodegradable Mg–1.5Zn–0.6Zr alloy
Source abstract
Abstract
Heretofore, recognitions of the systematic effects of scandium addition on corrosion behavior of biodegradable magnesium alloys are not yet clear. In the present study, a series of Mg–1.5Zn–0.6Zr–xSc (ZK21–xSc, x = 0, 0.2, 0.5, 1.0 wt.%) alloys were casted and investigated with respect to the immersion and electrochemical degradation behavior. The hydrogen evolution, pH monitoring, ion release and mass loss results demonstrated that ZK21–0.2Sc alloy exhibited the lowest corrosion rate. The surface morphology analyses displayed that an obvious uniform corrosion occurred in ZK21–xSc alloys with Sc content below 0.5, while localized corrosion occurred in ZK21–1.0Sc alloy. Corrosion potentials of ZK21–xSc alloys shifted toward more positive with the increasing Sc content. But ZK21–0.2Sc alloy exhibited the lowest corrosion current density and the largest corrosion film resistance. Compared with other developed Mg alloys, the ZK21–0.2Sc alloy demonstrated a superior degradation behavior.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Magnesium Alloys: Properties and Applications · Aluminum Alloys Composites Properties · Corrosion Behavior and Inhibition
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (46)
Show source-provided references
1. Zheng YF, Gu XN, Witte F (2014) Biodegradable metals. Mater Sci Eng R 77:1–3410.1016/j.mser.2014.01.001 ↗
2. Zhao D, Witte F, Lu F, Wang J, Li J, Qin L (2017) Current status on clinical applications of magnesium-based orthopaedic implants: a review from clinical translational perspective. Biomaterials 112:287–30210.1016/j.biomaterials.2016.10.017 ↗
3. Waizy H, Seitz J-M, Reifenrath J, Weizbauer A, Bach F-W, Meyer-Lindenberg A, Denkena B, Windhagen H (2013) Biodegradable magnesium implants for orthopedic applications. J Mater Sci 48:39–50. https://doi.org/10.1007/s10853-012-6572-210.1007/s10853-012-6572-2 ↗
4. Kim YK, Park IS, Lee KB, Lee SJ, Bae TS, Lee MH (2015) Characterization and biocompatibility of a calcium-containing AZ31B alloy as a biodegradable material. J Mater Sci 50:4672–4682. https://doi.org/10.1007/s10853-015-9018-910.1007/s10853-015-9018-9 ↗
5. Li JN, Cao P, Zhang XN, Zhang SX, He YH (2010) In vitro degradation and cell attachment of a PLGA coated biodegradable Mg–6Zn based alloy. J Mater Sci 45:6038–6045. https://doi.org/10.1007/s10853-010-4688-910.1007/s10853-010-4688-9 ↗
6. Silva CLP, Oliveira AC, Costa CGF, Figueiredo RB, Leite MD, Pereira MM, Lins VFC, Langdon TG (2017) Effect of severe plastic deformation on the biocompatibility and corrosion rate of pure magnesium. J Mater Sci 52:5992–6003. https://doi.org/10.1007/s10853-017-0835-x10.1007/s10853-017-0835-x ↗
7. Atrens A, Song GL, Liu M, Shi ZM, Cao FY, Dargusch MS (2015) Review of recent developments in the field of magnesium corrosion. Adv Eng Mater 17:400–45310.1002/adem.201400434 ↗
8. Gale WF, Totemeier TC (2004) Smithells metals reference book, 8th edn. Butterworth-Heinemann, Oxford
9. Ma N, Peng Q (2012) Influence of scandium on corrosion properties and electrochemical behaviour of Mg alloys in different media. Int J Electrochem Sci 7:8020–803410.1016/S1452-3981(23)17973-9 ↗
10. Brar HS, Ball JP, Berglund IS, Allen JB, Manuel MV (2013) A study of a biodegradable Mg–3Sc–3Y alloy and the effect of self-passivation on the in vitro degradation. Acta Biomater 9:5331–534010.1016/j.actbio.2012.08.004 ↗
11. Brar HS, Berglund IS, Allen JB, Manuel MV (2014) The role of surface oxidation on the degradation behavior of biodegradable Mg–RE (Gd, Y, Sc) alloys for resorbable implants. Mater Sci Eng C 40:407–41710.1016/j.msec.2014.03.055 ↗
12. Li T, Zhang H, He Y, Wen N, Wang X (2015) Microstructure, mechanical properties and in vitro degradation behavior of a novel biodegradable Mg–1.5Zn–0.6Zr–0.2Sc alloy. J Mater Sci Technol 31:744–75010.1016/j.jmst.2015.02.001 ↗
13. Li T, Zhang HL, Tang SQ, Yang YS, Zhou JX, Wang XT (2017) Improvement of mechanical properties and in vitro degradation resistance of biodegradable Mg–1.5Zn–0.6Zr–0.2Sc alloy by extrusion. Mater Sci Forum 898:236–24510.4028/www.scientific.net/MSF.898.236 ↗
14. Li T, He Y, Zhou J, Tang S, Yang Y, Wang X (2018) Influence of albumin on in vitro degradation behavior of biodegradable Mg–1.5Zn–0.6Zr–0.2Sc alloy. Mater Lett 217:227–23010.1016/j.matlet.2018.01.082 ↗
15. Li T, He Y, Zhou J, Tang S, Yang Y, Wang X (2018) Effects of scandium addition on biocompatibility of biodegradable Mg–1.5Zn–0.6Zr alloy. Mater Lett 215:200–20210.1016/j.matlet.2017.12.097 ↗
16. Zeng RC, Sun L, Zheng YF, Cui HZ, Han EH (2014) Corrosion and characterisation of dual phase Mg–Li–Ca alloy in Hank’s solution: the influence of microstructural features. Corros Sci 79:69–8210.1016/j.corsci.2013.10.028 ↗
17. Song GL, Atrens A (2003) Understanding magnesium corrosion—a framework for improved alloy performance. Adv Eng Mater 5:837–85810.1002/adem.200310405 ↗
18. Song G, Atrens A, StJohn D (2001) An hydrogen evolution method for the estimation of the corrosion rate of magnesium alloys. In: Mathaudhu SN, Luo AA, Neelameggham NR, Nyberg EA, Sillekens WH (eds) Essential readings in magnesium technology. Springer, Cham, pp 565–572
19. Han P, Cheng P, Zhang S, Zhao C, Ni J, Zhang Y, Zhong W, Hou P, Zhang X, Zheng Y, Chai Y (2015) In vitro and in vivo studies on the degradation of high-purity Mg (99.99wt.%) screw with femoral intracondylar fractured rabbit model. Biomaterials 64:57–6910.1016/j.biomaterials.2015.06.031 ↗
20. Shi Z, Liu M, Atrens A (2010) Measurement of the corrosion rate of magnesium alloys using Tafel extrapolation. Corros Sci 52:579–58810.1016/j.corsci.2009.10.016 ↗
21. Choubey A, Marton D, Sprague E (2009) Human aortic endothelial cell response to 316L stainless steel material microstructure. J Mater Sci Mater Med 20:2105–211610.1007/s10856-009-3780-7 ↗
22. Witte F, Hort N, Vogt C, Cohen S, Kainer KU, Willumeit R, Feyerabend F (2008) Degradable biomaterials based on magnesium corrosion. Curr Opin Solid State Mater Sci 12:63–7210.1016/j.cossms.2009.04.001 ↗
23. Song GL, Atrens A (1999) Corrosion mechanisms of magnesium alloys. Adv Eng Mater 1:11–3310.1002/(SICI)1527-2648(199909)1:1<11::AID-ADEM11>3.0.CO;2-N ↗
24. Alvarez-Lopez M, Pereda MD, del Valle JA, Fernandez-Lorenzo M, Garcia-Alonso MC, Ruano OA, Escudero ML (2010) Corrosion behaviour of AZ31 magnesium alloy with different grain sizes in simulated biological fluids. Acta Biomater 6:1763–177110.1016/j.actbio.2009.04.041 ↗
25. Zucchi F, Grassi V, Frignani A, Monticelli C, Trabanelli G (2006) Electrochemical behaviour of a magnesium alloy containing rare earth elements. J Appl Electrochem 36:195–20410.1007/s10800-005-9053-3 ↗
26. Arrabal R, Pardo A, Merino MC, Mohedano M, Casajús P, Paucar K, Garcés G (2012) Effect of Nd on the corrosion behaviour of AM50 and AZ91D magnesium alloys in 3.5wt.% NaCl solution. Corros Sci 55:301–31210.1016/j.corsci.2011.10.033 ↗
27. Xin Y, Hu T, Chu PK (2011) In vitro studies of biomedical magnesium alloys in a simulated physiological environment: a review. Acta Biomater 7:1452–145910.1016/j.actbio.2010.12.004 ↗
28. Jeong YS, Kim WJ (2014) Enhancement of mechanical properties and corrosion resistance of Mg–Ca alloys through microstructural refinement by indirect extrusion. Corros Sci 82:392–40310.1016/j.corsci.2014.01.041 ↗
29. Dinodi N, Nityananda Shetty A (2013) Electrochemical investigations on the corrosion behaviour of magnesium alloy ZE41 in a combined medium of chloride and sulphate. J Magnes Alloys 1:201–20910.1016/j.jma.2013.08.003 ↗
30. Zainal Abidin NI, Rolfe B, Owen H, Malisano J, Martin D, Hofstetter J, Uggowitzer PJ, Atrens A (2013) The in vivo and in vitro corrosion of high-purity magnesium and magnesium alloys WZ21 and AZ91. Corros Sci 75:354–36610.1016/j.corsci.2013.06.019 ↗
31. Johnston S, Shi Z, Atrens A (2015) The influence of pH on the corrosion rate of high-purity Mg, AZ91 and ZE41 in bicarbonate buffered Hanks’ solution. Corros Sci 101:182–19210.1016/j.corsci.2015.09.018 ↗
32. Hermawan H, Dubé D, Mantovani D (2010) Developments in metallic biodegradable stents. Acta Biomater 6:1693–169710.1016/j.actbio.2009.10.006 ↗
33. Ren YB, Huang JJ, Yang K, Zhang BC, Yao ZM, Wang H (2005) Study of bio-corrosion of pure magnesium. Acta Metall Sin 41:1228–1232
34. Liu CL, Wang YJ, Zeng RC, Zhang XM, Huang WJ, Chu PK (2010) In vitro corrosion degradation behaviour of Mg–Ca alloy in the presence of albumin. Corros Sci 52:3341–334710.1016/j.corsci.2010.06.003 ↗
35. Hou RQ, Scharnagl N, Feyerabend F, Willumeit-Römer R (2018) Exploring the effects of organic molecules on the degradation of magnesium under cell culture conditions. Corros Sci 132:35–4510.1016/j.corsci.2017.12.023 ↗
36. Zeng RC, Li XT, Li SQ, Zhang F, Han EH (2015) In vitro degradation of pure Mg in response to glucose. Sci Rep 5:1302610.1038/srep13026 ↗
37. Wang Y, Cui LY, Zeng RC, Li S-Q, Zou YH, Han EH (2017) In vitro degradation of pure magnesium—the effects of glucose and/or amino acid. Materials 10:72510.3390/ma10070725 ↗
38. Witte F, Fischer J, Nellesen J, Crostack H-A, Kaese V, Pisch A, Beckmann F, Windhagen H (2006) In vitro and in vivo corrosion measurements of magnesium alloys. Biomaterials 27:1013–101810.1016/j.biomaterials.2005.07.037 ↗
39. Zainal Abidin NI, Atrens AD, Martin D, Atrens A (2011) Corrosion of high purity Mg, Mg2Zn0.2Mn, ZE41 and AZ91 in Hank’s solution at 37 °C. Corros Sci 53:3542–355610.1016/j.corsci.2011.06.030 ↗
40. Li T, He Y, Zhang H, Wang X (2014) Microstructure, mechanical property and in vitro biocorrosion behavior of single-phase biodegradable Mg–1.5Zn–0.6Zr alloy. J Magnes Alloys 2:181–18910.1016/j.jma.2014.05.006 ↗
41. Brar HS, Wong J, Manuel MV (2012) Investigation of the mechanical and degradation properties of Mg–Sr and Mg–Zn–Sr alloys for use as potential biodegradable implant materials. J Mech Behav Biomed Mater 7:87–9510.1016/j.jmbbm.2011.07.018 ↗
42. Zhang B, Hou Y, Wang X, Wang Y, Geng L (2011) Mechanical properties, degradation performance and cytotoxicity of Mg–Zn–Ca biomedical alloys with different compositions. Mater Sci Eng C 31:1667–167310.1016/j.msec.2011.07.015 ↗
43. Yin DS, Zhang EL, Zeng SY (2008) Effect of Zn on mechanical properties and corrosion properties of as-cast Mg–Mn alloy. Chin J Nonferrous Met 18:388–393 (in chinese)10.1016/S1003-6326(08)60068-0 ↗
44. Zhang E, Yang L (2008) Microstructure, mechanical properties and bio-corrosion properties of Mg–Zn–Mn–Ca alloy for biomedical application. Mater Sci Eng A 497:111–11810.1016/j.msea.2008.06.019 ↗
45. Zhang E, Yang L, Xu J, Chen H (2010) Microstructure, mechanical properties and bio-corrosion properties of Mg–Si(–Ca, Zn) alloy for biomedical application. Acta Biomater 6:1756–176210.1016/j.actbio.2009.11.024 ↗
46. Zong Y, Yuan G, Zhang X, Mao L, Niu J, Ding W (2012) Comparison of biodegradable behaviors of AZ31 and Mg–Nd–Zn–Zr alloys in Hank’s physiological solution. Mater Sci Eng B 177:395–40110.1016/j.mseb.2011.09.042 ↗