Development of cytocompatible antibacterial electro-spun nanofibrous composites
Source abstract
Abstract
This study presents a method of producing biocompatible nanofibrous composites containing antimicrobial polymers which have excellent antimicrobial efficacy. Specifically, antimicrobial cellulose acetate (CA) nanofibrous composites were prepared by adding poly[5,5-dimethyl-3-(3′-triethoxysilylpropyl)hydantoin] (PBA) to the CA solution using the electro-spinning technique followed with curing and exposure to diluted sodium hypochlorite. Scanning electron microscopy images demonstrated that CA nanofibers formed with diameters of 172 ± 62 nm. The chlorinated CA nanofibrous mats showed good UVA stability. The chlorinated CA nanofibrous mats completely inactivated Staphylococcus aureus (gram-positive) and Escherichia coli O157:H7 (gram-negative) within 30 min of contact time. The cell culture assay showed that the N-halamine-modified CA nanofibrous composites are non-toxic in vitro.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Antimicrobial agents and applications · Electrospun Nanofibers in Biomedical Applications · biodegradable polymer synthesis and properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (40)
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