Novel trends and recent progress on preparation methods of biodegradable metallic foams for biomedicine: a review
Source abstract
Abstract
Porous degradable metallic biomaterials are attracting considerable attention as promising bone implant materials. Recently, the interest in developing new biomaterials with enhanced performance stimulates the widespread development of fabricating techniques for porous metals. In this work, the recent progress and novel trends on preparation methods of metallic foams for biomedicine were systematically reviewed. The common synthesis methods for porous Mg, Fe, Zn, and their alloys intended for orthopedic applications are comprehensively discussed and compared. The advantages and disadvantages of relevant manufacturing strategies are evaluated. While the modern techniques enable fabrication of complex porous structures and customized shapes, the cost-effective and easy controllable approach are major benefits of traditional methods. Main structural characteristics and properties of biomaterials fabricated using different routes are also presented. Furthermore, the future research directions and current challenges are mentioned. The ambition of this review article is to provide useful guidelines for researchers to choose suitable manufacturing technique to prepare materials with desired structural topology and mechanical, and degradation properties.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Magnesium Alloys: Properties and Applications · Aluminum Alloys Composites Properties · Bone Tissue Engineering Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Eurostat (hlth_co_proc2) https://ec.europa.eu/eurostat/web/products-datasets/-/hlth_co_proc2
2. Beaty JH (2009) The future of orthopedics. J Orthop Sci 14:245–247. https://doi.org/10.1007/s00776-008-1320-910.1007/s00776-008-1320-9 ↗
3. Dolcimascolo A, Calabrese G, Conoci S, Parenti R (2019) Innovative Biomaterials for Tissue Engineering. In: Barbeck M (ed) Biomaterial-supported Tissue Reconstruction or Regeneration. IntechOpen, pp 1–18. DOI: https://doi.org/10.5772/intechopen.8383910.5772/intechopen.83839 ↗
4. Ivanova EP, Bazaka K, Crawford RJ (2014) Metallic biomaterials: types and advanced applications. In: New Functional Biomaterials for Medicine and Healthcare. Woodhead Publishing Limited, pp 121–147. https://doi.org/10.1533/9781782422662.12110.1533/9781782422662.121 ↗
5. Hayes JS, Richards RG (2019) Osseointegration of permanent and temporary orthopedic implants. In: Narayan R (ed) Encyclopedia of biomedical engineering, vol 1, Biomaterials: in vitro and in vivo studies of biomaterials. Elsevier, Amsterdam, pp 257–269. https://doi.org/10.1016/B978-0-12-801238-3.00225-710.1016/B978-0-12-801238-3.00225-7 ↗
6. Rahim MI, Ullah S, Mueller PP (2018) Advances and challenges of biodegradable implant materials with a focus on magnesium-alloys and bacterial infections. Metals 8:532. https://doi.org/10.3390/met807053210.3390/met8070532 ↗
7. Hermawan H (2018) Updates on the research and development of absorbable metals for biomedical applications. Prog Biomater 7:93–110. https://doi.org/10.1007/s40204-018-0091-410.1007/s40204-018-0091-4 ↗
8. Salerno A, Netti PA (2014) Introduction to biomedical foams. In: Netti PA (ed) Biomedical Foams for Tissue Engineering Applications. Woodhead Publishing Limited, pp 3–39. https://doi.org/10.1533/9780857097033.1.310.1533/9780857097033.1.3 ↗
9. Hench LL (2005) Bioceramics. J Am Ceram Soc 81:1705–1728. https://doi.org/10.1111/j.1151-2916.1998.tb02540.x10.1111/j.1151-2916.1998.tb02540.x ↗
10. Niinomi M (2008) Metallic biomaterials. J Artif Organs 11:105–110. https://doi.org/10.1007/s10047-008-0422-710.1007/s10047-008-0422-7 ↗
11. Staiger MP, Pietak AM, Huadmai J, Dias G (2006) Magnesium and its alloys as orthopedic biomaterials: a review. Biomaterials 27:1728–1734. https://doi.org/10.1016/j.biomaterials.2005.10.00310.1016/j.biomaterials.2005.10.003 ↗
12. Tan L, Yu X, Wan P, Yang K (2013) Biodegradable Materials for Bone Repairs: A Review. J Mater Sci Technol 29:503–513. https://doi.org/10.1016/j.jmst.2013.03.00210.1016/j.jmst.2013.03.002 ↗
13. Ashammakhi N, Rokkanen P (1997) Absorbable polyglycolide devices in trauma and bone surgery. Biomaterials 18:3–9. https://doi.org/10.1016/S0142-9612(96)00107-X10.1016/S0142-9612(96)00107-X ↗
14. Wong HM, Yeung KWK, Lam KO, Tam V, Chu PK, Luk KDK, Cheung KMC (2010) A biodegradable polymer-based coating to control the performance of magnesium alloy orthopaedic implants. Biomaterials 31:2084–2096. https://doi.org/10.1016/j.biomaterials.2009.11.11110.1016/j.biomaterials.2009.11.111 ↗
15. Witte F, Ulrich H, Rudert M, Willbold E (2007) Biodegradable magnesium scaffolds: Part 1: Appropriate inflammatory response. J Biomed Mater Res Part A 81A:748–756. https://doi.org/10.1002/jbm.a.3117010.1002/jbm.a.31170 ↗
16. Hench LL, Polak JM (2002) Third-generation biomedical materials. Science 295:1014–1017. https://doi.org/10.1126/science.106740410.1126/science.1067404 ↗
17. Hrubovčáková M, Kupková M, Džupon M (2016) Fe and Fe-P foam for biodegradable bone replacement material: morphology, corrosion behaviour, and mechanical properties. Adv Mater Sci Eng 2016:6257368. https://doi.org/10.1155/2016/625736810.1155/2016/6257368 ↗
18. Popescu IN, Vidu R, Bratu V (2017) Porous metallic biomaterials processing (Review) Part 1: compaction, sintering behavior, properties and medical applications. Sci Bull Valahia Univ Mater Mech 15:28–40. https://doi.org/10.1515/bsmm-2017-001510.1515/bsmm-2017-0015 ↗
19. Puppi D, Chiellini F, Piras AM, Chiellini E (2010) Polymeric materials for bone and cartilage repair. Prog Polym Sci 35:403–440. https://doi.org/10.1016/j.progpolymsci.2010.01.00610.1016/j.progpolymsci.2010.01.006 ↗
20. Ryan G, Pandit A, Apatsidis D (2006) Fabrication methods of porous metals for use in orthopaedic applications. Biomaterials 27:2651–2670. https://doi.org/10.1016/j.biomaterials.2005.12.00210.1016/j.biomaterials.2005.12.002 ↗
21. Yusop AH, Bakir AA, Shaharom NA, Abdul Kadir MR, Hermawan H (2012) Porous biodegradable metals for hard tissue scaffolds: A review. Int J Biomater 2012. https://doi.org/10.1155/2012/64143010.1155/2012/641430 ↗
22. Chang CH, Lin FH, Kuo TF, Liu HC (2005) Cartilage tissue engineering. Biomed Eng Appl Basis Commun 17:61–71. https://doi.org/10.4015/S101623720500010X10.4015/S101623720500010X ↗
23. Risbud MV, Sittinger M (2002) Tissue engineering: advances in in vitro cartilage generation. Trends Biotechnol 20:351–356. https://doi.org/10.1016/S0167-7799(02)02016-410.1016/S0167-7799(02)02016-4 ↗
24. Liao JD, Lee H, Yao CK (2013) Powder metallurgy based porous metal biomaterials. J Powder Metall Min 2:109. https://doi.org/10.4172/2168-9806.100010910.4172/2168-9806.1000109 ↗
25. Goodall R (2013) Porous metals: foams and sponges. In: Chang I, Zhao Y (eds) Advances in Powder Metallurgy, Properties, processing and applications, Chapter 10, Woodhead Publishing Limited, pp 273–307. DOI: https://doi.org/10.1533/9780857098900.2.27310.1533/9780857098900.2.273 ↗
26. Shuai C, Li S, Peng S, Feng P, Lai Y, Gao C (2019) Biodegradable metallic bone implants. Mater Chem Front 3:544–562. https://doi.org/10.1039/c8qm00507a10.1039/c8qm00507a ↗
27. Han Y, Choi J, Kim H-S, Kim H, Park J (2013) Control of pore and window size of ceramic foams with tri-modal pore structure: Influence of agar concentration. Mater Lett 110:256–259. https://doi.org/10.1016/j.matlet.2013.05.10010.1016/j.matlet.2013.05.100 ↗
28. Rouwkema J, Rivron NC, Van Blitterswijk CA (2008) Vascularization in tissue engineering. Trends Biotechnol 26:434–441. https://doi.org/10.1016/j.tibtech.2008.04.00910.1016/j.tibtech.2008.04.009 ↗
29. Murphy CM, Haugh MG, O’Brien FJ (2010) The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering. Biomaterials 31:461–466. https://doi.org/10.1016/j.biomaterials.2009.09.06310.1016/j.biomaterials.2009.09.063 ↗
30. Wu S, Liu X, Yeung KWK, Liu C, Yang X (2014) Biomimetic porous scaffolds for bone tissue engineering. Mater Sci Eng R 80:1–36. https://doi.org/10.1016/j.mser.2014.04.00110.1016/j.mser.2014.04.001 ↗
31. Xie Y, Zhao L, Zhang Z, Wang X, Wang R, Cui C (2018) Fabrication and properties of porous Zn-Ag alloy scaffolds as biodegradable materials. Mater Chem Phys 219:433–443. https://doi.org/10.1016/j.matchemphys.2018.08.02310.1016/j.matchemphys.2018.08.023 ↗
32. Čapek J, Jablonská E, Lipov J, Kubatík TF, Vojtěch D (2018) Preparation and characterization of porous zinc prepared by spark plasma sintering as a material for biodegradable scaffolds. Mater Chem Phys 203:249–258. https://doi.org/10.1016/j.matchemphys.2017.10.00810.1016/j.matchemphys.2017.10.008 ↗
33. Gorejová R, Haverová L, Oriňaková R, Oriňak A, Oriňak M (2019) Recent advancements in Fe-based biodegradable materials for bone repair. J Mater Sci 54:1913–1947. https://doi.org/10.1007/s10853-018-3011-z10.1007/s10853-018-3011-z ↗
34. Oriňaková R, Gorejová R, Orságová Králová Z, Oriňak A (2020) Surface modifications of biodegradable metallic foams for medical applications. Coatings 10:819. https://doi.org/10.3390/coatings1009081910.3390/coatings10090819 ↗
35. Venezuela J, Dargusch MS (2019) The influence of alloying and fabrication techniques on the mechanical properties, biodegradability and biocompatibility of zinc: a comprehensive review. Acta Biomater 87:1–40. https://doi.org/10.1016/j.actbio.2019.01.03510.1016/j.actbio.2019.01.035 ↗
36. Pierson D, Edick J, Tauscher A, Pokorney E, Bowen P, Gelbaugh J, Stinson J, Getty H, Lee CH, Drelich J, Goldman J (2012) A simplified in vivo approach for evaluating the bioabsorbable behavior of candidate stent materials. J Biomed Mater Res B Appl Biomater 100:58–67. https://doi.org/10.1002/jbm.b.3192210.1002/jbm.b.31922 ↗
37. Gu X, Zheng Y, Cheng Y, Zhong S, Xi T (2009) In vitro corrosion and biocompatibility of binary magnesium alloys. Biomaterials 30:484–498. https://doi.org/10.1016/j.biomaterials.2008.10.02110.1016/j.biomaterials.2008.10.021 ↗
38. Radha R, Sreekanth D (2017) Insight of magnesium alloys and composites for orthopedic implant applications – a review. J Magnes Alloy 5:286–312. https://doi.org/10.1016/j.jma.2017.08.00310.1016/j.jma.2017.08.003 ↗
39. Erryani A, Pramuji F, Annur D, Amal MI, Kartika I (2017) Microstructures and Mechanical Study of Mg Alloy Foam Based on Mg-Zn-Ca-CaCO3. IOP Conf Ser: Mater Sci Eng 202. https://doi.org/10.1088/1757-899X/202/1/01202810.1088/1757-899X/202/1/012028 ↗
40. Malladi L, Mahapatro A, Gomes AS (2018) Fabrication of magnesium-based metallic scaffolds for bone tissue engineering. Mater Technol 33:173–182. https://doi.org/10.1080/10667857.2017.140427810.1080/10667857.2017.1404278 ↗
41. Banhart J, Baumeister J (1998) Production methods for metallic foams. Mater Res Soc Symp Proc 521:121–132. https://doi.org/10.1557/proc-521-12110.1557/proc-521-121 ↗
42. Banhart J (2007) Metal Foams—from Fundamental Research to Applications. In: Raj B, Ranganathan S, Bhanu Sankara Rao K, Matthew MD, Shankar P (eds) Frontiers in the Design of Materials, Universities Press Limited, India, pp 279–289. ISBN 9781420047301
43. Yang D, Seo C, Hur BY (2008) Mg alloy foam fabrication via melt foaming method. J Mater Sci Technol 24:302–304. https://www.jmst.org/EN/Y2008/V24/I03/302
44. Tane M, Nakajima H (2008) Fabrication of porous magnesium with directional pores through use of hydrogen thermally decomposed from MgH2 powders during unidirectional solidification. J Mater Res 23:849–855. https://doi.org/10.1557/jmr.2008.010510.1557/jmr.2008.0105 ↗
45. Yang DH, Hur BY, Yang SR (2008) Study on fabrication and foaming mechanism of Mg foam using CaCO3 as blowing agent. J Alloys Compd 461:221–227. https://doi.org/10.1016/j.jallcom.2007.07.09810.1016/j.jallcom.2007.07.098 ↗
46. Vahidgolpayegani A, Wen C, Hodgson P, Li Y (2017) Production methods and characterization of porous Mg and Mg alloys for biomedical applications. In: Wen C (ed) Metallic foam bone: processing, modification and characterization and properties. Woodhead Publishing, Duxford, Eng, pp 25–82. https://doi.org/10.1016/B978-0-08-101289-5.00002-010.1016/B978-0-08-101289-5.00002-0 ↗
47. Xu ZG, Fu JW, Luo TJ, Yang YS (2012) Effects of cell size on quasi-static compressive properties of Mg alloy foams. Mater Des 34:40–44. https://doi.org/10.1016/j.matdes.2011.07.06610.1016/j.matdes.2011.07.066 ↗
48. Yuan L, Yanxiang L, Jiang W, Huawei Z (2005) Evaluation of porosity in lotus-type porous magnesium fabricated by metal/gas eutectic unidirectional solidification. Mater Sci Eng A 402:47–54. https://doi.org/10.1016/j.msea.2005.03.10710.1016/j.msea.2005.03.107 ↗
49. Zhou C, Liu Y, Zhang H, Chen X, Li Y (2020) Compressive and corrosion properties of Lotus-type porous Mg-Mn alloys fabricated by unidirectional solidification. Metall Mater Trans A Phys Metall Mater Sci 51:3238–3247. https://doi.org/10.1007/s11661-020-05732-110.1007/s11661-020-05732-1 ↗
50. Zhang YQ, Li Y, Liu H, Bai J, Bao NR, Zhang Y, He P, Zhao JN, Tao L, Xue F, Zhou GX, Fan GT (2018) Mechanical and biological properties of a biodegradable Mg-Zn-Ca porous alloy. Orthop Surg 10:160–168. https://doi.org/10.1111/os.1237810.1111/os.12378 ↗
51. Bach F, Bormann D, Kucharski R, Meyer-Lindenberg A (2007) Magnesium sponges as a bioabsorbable material—attributes and challenges. Int J Mat Res 98:609–612. https://doi.org/10.3139/146.10151410.3139/146.101514 ↗
52. Lietaert K, Weber L, Van Humbeeck J, Mortensen A, Luyten J, Schrooten J (2013) Open cellular magnesium alloys for biodegradable orthopaedic implants. J Magnes Alloy 1:303–311. https://doi.org/10.1016/j.jma.2013.11.00410.1016/j.jma.2013.11.004 ↗
53. Atrens A, Liu M, Zainal Abidin NI (2011) Corrosion mechanism applicable to biodegradable magnesium implants. Mater Sci Eng B Solid-State Mater Adv Technol 176:1609–1636. https://doi.org/10.1016/j.mseb.2010.12.01710.1016/j.mseb.2010.12.017 ↗
54. Yue X-Z, Kitazono K, Yue X-J, Hur B-Y (2016) Effect of fluidity on the manufacturing of open cell magnesium alloy foams. J Magnes Alloys 4:1–7. https://doi.org/10.1016/j.jma.2015.11.00710.1016/j.jma.2015.11.007 ↗
55. Witte F, Reifenrath J, Müller PP, Crostack HA, Nellesen J, Bach FW, Bormann D, Rudert M (2006) Cartilage repair on magnesium scaffolds used as a subchondral bone replacement. Materwiss Werksttech 37:504–508. https://doi.org/10.1002/mawe.20060002710.1002/mawe.200600027 ↗
56. Ferri JM, Molina JM, Louis E (2015) Fabrication of Mg foams for biomedical applications by means of a replica method based upon spherical carbon particles. Biomed Phys Eng Express 1. https://doi.org/10.1088/2057-1976/1/4/04500210.1088/2057-1976/1/4/045002 ↗
57. Posada VM, Orozco C, Ramirez Patino JF, Fernandez-Morales P (2018) Human bone inspired design of an Mg Alloy-based foam. Mater Sci Forum 933:291–296. https://doi.org/10.4028/www.scientific.net/msf.933.29110.4028/www.scientific.net/msf.933.291 ↗
58. Wen CE, Yamada Y, Shimojima K, Chino Y, Hosokawa H, Mabuchi M (2004) Compressibility of porous magnesium foam: dependency on porosity and pore size. Mater Lett 58:357–360. https://doi.org/10.1016/S0167-577X(03)00500-710.1016/S0167-577X(03)00500-7 ↗
59. Zhuang H, Han Y, Feng A (2008) Preparation, mechanical properties and in vitro biodegradation of porous magnesium scaffolds. Mater Sci Eng C 28:1462–1466. https://doi.org/10.1016/j.msec.2008.04.00110.1016/j.msec.2008.04.001 ↗
60. Seyedraoufi ZS, Mirdamadi S (2013) Synthesis, microstructure and mechanical properties of porous Mg-Zn scaffolds. J Mech Behav Biomed Mater 21:1–8. https://doi.org/10.1016/j.jmbbm.2013.01.02310.1016/j.jmbbm.2013.01.023 ↗
61. Wen CE, Mabuchi M, Yamada Y, Shimojima K, Chino Y, Asahina T (2001) Processing of biocompatible porous Ti and Mg. Scr Mater 45:1147–1153. https://doi.org/10.1016/S1359-6462(01)01132-010.1016/S1359-6462(01)01132-0 ↗
62. Liu C, Wang J, Gao C, Wang Z, Zhou X, Tang M, Yu K, Deng Y (2020) Enhanced osteoinductivity and corrosion resistance of dopamine/gelatin/rhBMP-2–coated β-TCP/Mg-Zn orthopedic implants: An in vitro and in vivo study. PLoS ONE 15:1–24. https://doi.org/10.1371/journal.pone.022824710.1371/journal.pone.0228247 ↗
63. Kang MH, Lee H, Jang TS, Seong YJ, Kim HE, Koh YH, Song J, Do Jung H (2019) Biomimetic porous Mg with tunable mechanical properties and biodegradation rates for bone regeneration. Acta Mater 84:453–467. https://doi.org/10.1016/j.actbio.2018.11.04510.1016/j.actbio.2018.11.045 ↗
64. Angelini E, De Benedetti B, Fulginiti D, Grassini S, Ferraris F, Parvis M (2015) Development and characterization of porous magnesium bioresorbable implants. 2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings. Turin 2015:633–638. https://doi.org/10.1109/MeMeA.2015.714528010.1109/MeMeA.2015.7145280 ↗
65. Sezer N, Evis Z, Koç M (2020) Additive manufacturing of biodegradable magnesium implants and scaffolds: Review of the recent advances and research trends. In Press, J Magnes Alloys. https://doi.org/10.1016/j.jma.2020.09.01410.1016/j.jma.2020.09.014 ↗
66. Li Y, Zhou J, Pavanram P, Leeflang MA, Fockaert LI, Pouran B, Tümer N, Schröder KU, Mol JMC, Weinans H, Jahr H, Zadpoor AA (2018) Additively manufactured biodegradable porous magnesium. Acta Biomater 67:378–392. https://doi.org/10.1016/j.actbio.2017.12.00810.1016/j.actbio.2017.12.008 ↗
67. Jasmawati N, Djuansjah JRP, Kadir MRA, Sukmana I (2015) Porous magnesium scaffolds for bone implant applications: a review. Adv Mater Res 1125:437–440. https://doi.org/10.4028/www.scientific.net/amr.1125.43710.4028/www.scientific.net/amr.1125.437 ↗
68. Yang Y, He C, Dianyu E, Yang W, Qi F, Xie D, Shen L, Peng S, Shuai C (2020) Mg bone implant: Features, developments and perspectives. Mater Des 185. https://doi.org/10.1016/j.matdes.2019.10825910.1016/j.matdes.2019.108259 ↗
69. Zhang M, Chen C, Liu C, Wang S (2018) Study on porous Mg-Zn-Zr ZK61 alloys produced by laser additive manufacturing. Metals 8:635. https://doi.org/10.3390/met808063510.3390/met8080635 ↗
70. Yang Y, Wu P, Lin X, Liu Y, Bian H, Zhou Y, Gao C, Shuai C (2016) System development, formability quality and microstructure evolution of selective laser-melted magnesium. Virtual Phys Prototyp 11:173–181. https://doi.org/10.1080/17452759.2016.121052210.1080/17452759.2016.1210522 ↗
71. Hu D, Wang Y, Zhang D, Hao L, Jiang J, Li Z, Chen Y (2015) Experimental investigation on selective laser melting of bulk net-shape pure magnesium. Mater Manuf Process 30:1298–1304. https://doi.org/10.1080/10426914.2015.102596310.1080/10426914.2015.1025963 ↗
72. Nguyen TL, Staiger MP, Dias GJ, Woodfield TBF (2011) A novel manufacturing route for fabrication of topologically-ordered porous magnesium scaffolds. Adv Eng Mater 13:872–881. https://doi.org/10.1002/adem.20110002910.1002/adem.201100029 ↗
73. Staiger MP, Kolbeinsson I, Kirkland NT, Nguyen T, Dias G, Woodfield TBF (2010) Synthesis of topologically-ordered open-cell porous magnesium. Mater Lett 64:2572–2574. https://doi.org/10.1016/j.matlet.2010.08.04910.1016/j.matlet.2010.08.049 ↗
74. Kirkland NT, Kolbeinsson I, Woodfield T, Dias G, Staiger MP (2009) Processing-property relationships of as-cast magnesium foams with controllable architecture. Int J Mod Phys B 23:1002–1008. https://doi.org/10.1142/S021797920906037310.1142/S0217979209060373 ↗
75. Čapek J, Vojtěch D, Oborná A (2015) Microstructural and mechanical properties of biodegradable iron foam prepared by powder metallurgy. Mater Des 83:468–482. https://doi.org/10.1016/j.matdes.2015.06.02210.1016/j.matdes.2015.06.022 ↗
76. Čapek J, Vojtěch D (2014) Microstructural and mechanical characteristics of porous iron prepared by powder metallurgy. Mater Sci Eng C 43:494–501. https://doi.org/10.1016/j.msec.2014.06.04610.1016/j.msec.2014.06.046 ↗
77. Zivic F, Grujovic N, Pellicer E, Sort J, Mirovic S, Adamovic D, Vulovic M (2017) Biodegradable Metals as Biomaterials for Clinical Practice: Iron-Based Materials. In: Zivic F, Affatato S, Trajanovic M, Schnabelrauch M, Grujovic N, Choy K (eds) Biomaterials in Clinical Practice. Springer, Cham, pp 225–280. https://doi.org/10.1007/978-3-319-68025-5_910.1007/978-3-319-68025-5_9 ↗
78. He J, He FL, Li DW, Liu YL, Liu YY, Ye YJ, Yin DC (2016) Advances in Fe-based biodegradable metallic material. RSC Adv 6:112819–112838. https://doi.org/10.1039/C6RA20594A10.1039/C6RA20594A ↗
79. Oriňak A, Oriňaková R, Orságová Králová Z, Turoňová Morovská A, Kupková M, Hrubovčáková M, Radoňák J, Džunda R (2014) Sintered metallic foams for biodegradable bone replacement. J Porous Mater 21:131–140. https://doi.org/10.1007/s10934-013-9757-410.1007/s10934-013-9757-4 ↗
80. Oriňaková R, Oriňak A, Markušová-Bučková L, Giretová M, Medvecký L, Labbanczová E, Kupková M, Hrubovčáková M, Koval K (2013) Iron based degradable foam structures for potential orthopedic application. Int J Electrochem Sci 8:12451–1246510.1016/S1452-3981(23)13279-2 ↗
81. Haverová L, Oriňaková R, Oriňak A, Gorejová R, Baláž M, Vanýsek P, Kupková M, Hrubovčáková M, Mudroň P, Radoňák J, Orságová Králová Z, Morovská Turoňová A (2018) An in vitro corrosion study of open cell Iron structures with PEG coating for bone replacement applications. Metals 8:499. https://doi.org/10.3390/met807049910.3390/met8070499 ↗
82. Ray S, Thormann U, Eichelroth M, Budak M, Biehl C, Rupp M, Sommer U, El Khassawna T, Alagboso FI, Kampschulte M, Rohnke M, Henß A, Peppler K, Linke V, Quadbeck P, Voigt A, Stenger F, Karl D, Schnettler R, Heiss C, Lips KS, Alt V (2018) Strontium and bisphosphonate coated iron foam scaffolds for osteoporotic fracture defect healing. Biomaterials 157:1–16. https://doi.org/10.1016/j.biomaterials.2017.11.04910.1016/j.biomaterials.2017.11.049 ↗
83. Quadbeck P, Stephani G, Kümmel K, Adler J, Standke G (2007) Synthesis and properties of open-celled metal foams. Mater Sci Forum 534–536:1005–1008. https://doi.org/10.4028/www.scientific.net/msf.534-536.100510.4028/www.scientific.net/msf.534-536.1005 ↗
84. Hrubovčáková M, Kupková M, Džupon M, Giretová M, Medvecký L, Džunda R (2017) Biodegradable polylactic acid and polylactic acid/hydroxyapatite coated iron foams for bone replacement materials. Int J Electrochem Sci 12:11122–11136. https://doi.org/10.20964/2017.12.5310.20964/2017.12.53 ↗
85. Gorejová R, Oriňaková R, Orságová Králová Z, Baláž M, Kupková M, Hrubovčáková M, Haverová L, Džupon M, Oriňak A, Kaľavský F, Kovaľ K (2020) In vitro corrosion behavior of biodegradable iron foams with polymeric coating. Materials 13:184. https://doi.org/10.3390/ma1301018410.3390/ma13010184 ↗
86. Quadbeck P, Kümmel K, Hauser R, Standke G, Adler J, Stephani G, Kieback B (2011) Structural and material design of open-cell powder metallurgical foams. Adv Eng Mater 13:1024–1030. https://doi.org/10.1002/adem.20110002310.1002/adem.201100023 ↗
87. Feng Y, Fornell J, Zhang H, Solsona P, Baró MD, Suriñach S, Pellicer E, Sort J (2018) Synthesis of α-Fe2O3 and Fe-Mn oxide foams with highly tunable magnetic properties by the replication method from polyurethane templates. Materials 11:280. https://doi.org/10.3390/ma1102028010.3390/ma11020280 ↗
88. Oriňaková R, Gorejová R, Orságová Králová Z, Haverová L, Oriňak A, Maskaľová I, Kupková M, Džupon M, Baláž M, Hrubovčáková M, Sopčák T, Zubrik A, Oriňak M (2020) Evaluation of Mechanical Properties and Hemocompatibility of Open Cell Iron Foams with Polyethylene Glycol Coating. Appl Surf Sci 505. https://doi.org/10.1016/j.apsusc.2019.14463410.1016/j.apsusc.2019.144634 ↗
89. Oriňaková R, Gorejová R, Petráková M, Orságová Králová Z, Oriňak A, Kupková M, Hrubovčáková M, Podobová M, Baláž M, Smith RM (2020) Degradation performance of open-cell biomaterials from phosphated carbonyl iron powder with PEG coating. Materials 13:4134. https://doi.org/10.3390/ma1318413410.3390/ma13184134 ↗
90. Hrubovčáková M, Džupon M, Kupková M, Oriňaková R (2020) Biodegradable iron-based foams for potential bone replacement material. Defect Diffus Forum 405:151–156. https://doi.org/10.4028/www.scientific.net/DDF.405.15110.4028/www.scientific.net/DDF.405.151 ↗
91. Kupková M, Kupka M, Oriňaková R, Gorejová R (2020) Microstructure, stiffness and corrosion of bare and phosphated specimens made by sintering of structured iron-iron oxide spheres. Defect Diffus Forum 405:411–416. https://doi.org/10.4028/www.scientific.net/DDF.405.41110.4028/www.scientific.net/DDF.405.411 ↗
92. Jee CSY, Özgüven N, Guo ZX, Evans JRG (2000) Preparation of high porosity metal foams. Metall Mater Trans B Process Metall Mater Process Sci 31:1345–1352. https://doi.org/10.1007/s11663-000-0021-310.1007/s11663-000-0021-3 ↗
93. Čapek J, Msallamová Š, Jablonská E, Lipov J, Vojtěch D (2017) A novel high-strength and highly corrosive biodegradable Fe-Pd alloy: structural, mechanical and in vitro corrosion and cytotoxicity study. Mater Sci Eng C 79:550–562. https://doi.org/10.1016/j.msec.2017.05.10010.1016/j.msec.2017.05.100 ↗
94. Zhang Q, Peng C (2015) Degradable porous Fe-35wt.%Mn produced via powder sintering from NH4HCO3 porogen. Mater Chem Phys 163:394–401. https://doi.org/10.1016/j.matchemphys.2015.07.05610.1016/j.matchemphys.2015.07.056 ↗
95. Heiden M, Nauman E, Stanciu L (2017) Bioresorbable Fe–Mn and Fe–Mn–HA Materials for Orthopedic Implantation: Enhancing Degradation through Porosity Control. Adv Healthc Mater 6:1700120. https://doi.org/10.1002/adhm.20170012010.1002/adhm.201700120 ↗
96. Murakami T, Ohara K, Narushima T, Ouchi C (2007) Development of a new method for manufacturing iron foam using gases generated by reduction of iron oxide. Mater Trans 48:2937–2944. https://doi.org/10.2320/matertrans.MRA200712710.2320/matertrans.MRA2007127 ↗
97. Carluccio D, Demir AG, Caprio L, Previtali B, Bermingham MJ, Dargusch MS (2019) The influence of laser processing parameters on the densification and surface morphology of pure Fe and Fe-35Mn scaffolds produced by selective laser melting. J Manuf Process 40:113–121. https://doi.org/10.1016/j.jmapro.2019.03.01810.1016/j.jmapro.2019.03.018 ↗
98. Carluccio D, Xu C, Venezuela J, Cao Y, Kent D, Bermingham M, Demir AG, Previtali B, Ye Q, Dargusch M (2020) Additively manufactured iron-manganese for biodegradable porous load-bearing bone scaffold applications. Acta Biomater 103:346–360. https://doi.org/10.1016/j.actbio.2019.12.01810.1016/j.actbio.2019.12.018 ↗
99. Li Y, Jahr H, Pavanram P, Bobbert FSL, Puggi U, Zhang XY, Pouran B, Leeflang MA, Weinans H, Zhou J, Zadpoor AA (2019) Additively manufactured functionally graded biodegradable porous iron. Acta Biomater 96:646–661. https://doi.org/10.1016/j.actbio.2019.07.01310.1016/j.actbio.2019.07.013 ↗
100. Li Y, Jahr H, Lietaert K, Pavanram P, Yilmaz A, Fockaert LI, Leeflang MA, Pouran B, Gonzalez-Garcia Y, Weinans H, Mol JMC, Zhou J, Zadpoor AA (2018) Additively manufactured biodegradable porous iron. Acta Biomater 77:380–393. https://doi.org/10.1016/j.actbio.2018.07.01110.1016/j.actbio.2018.07.011 ↗