Synthesis, multicolour tuning, and emission enhancement of ultrasmall LaF3:Yb3+/Ln3+ (Ln = Er, Tm, and Ho) upconversion nanoparticles
Source abstract
Abstract
The development of efficient sub-10 nm ultrasmall upconversion nanoparticles will open the door to the exciting application in biological labelling and imaging. In this paper, we demonstrated a facile method for the synthesis of monodisperse sub-10 nm hexagonal-phased LaF3 nanoparticles doped with upconverting lanthanide ions (Yb3+/Ln3+, Ln = Er3+, Tm3+, and Ho3+). The particle size of the as-synthesized LaF3 nanoparticles can be tuned by varying the preparation temperature. Upon excitation at 980 nm, the LaF3:Yb3+/Ln3+ nanoparticles showed intense upconversion emissions, and the colour output can be precisely modulated by changing the species and concentration of the lanthanide activators. In order to further enhance the upconversion emission intensity of the ultrasmall LaF3:Yb3+/Ln3+ nanoparticles, we adopted the strategy of core–shell nanostructured design to minimize the surface quenching effect. After coating an inert LaF3 shell, a maximum ninefold enhancement in upconversion luminescence was achieved under 980 nm excitation. These as-prepared lanthanide-doped LaF3 upconversion nanoparticles may find promising applications in biomedicine fields as luminescent nanoprobes.
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Research context
OpenAlex topics: Luminescence Properties of Advanced Materials · Radiation Detection and Scintillator Technologies · Luminescence and Fluorescent Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (46)
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1. Liu X, Yan C-H, Capobianco JA (2015) Photon upconversion nanomaterials. Chem Soc Rev 44:1299. doi: 10.1039/C5CS90009C10.1039/C5CS90009C ↗
2. Liu Y, Tu D, Zhu H, Chen X (2013) Lanthanide-doped luminescent nanoprobes: controlled synthesis, optical spectroscopy, and bioapplications. Chem Soc Rev 42:6924. doi: 10.1039/C3CS60060B10.1039/c3cs60060b ↗
3. Zeng S, Wang H, Lu W et al (2014) Dual-modal upconversion fluorescent/X-ray imaging using ligand-free hexagonal phase NaLuF4:Gd/Yb/Er nanorods for blood vessel visualization. Biomaterials 35:2934. doi: 10.1016/j.biomaterials.2013.11.08210.1016/j.biomaterials.2013.11.082 ↗
4. Zhou J, Liu Z, Li F (2012) Upconversion nanophosphors for small-animal imaging. Chem Soc Rev 41:1323. doi: 10.1039/C1CS15187H10.1039/C1CS15187H ↗
5. Wei Z, Sun L, Liu J et al (2014) Cysteine modified rare-earth up-converting nanoparticles for in vitro and in vivo bioimaging. Biomaterials 35:387. doi: 10.1016/j.biomaterials.2013.09.11010.1016/j.biomaterials.2013.09.110 ↗
6. Yang D, P Ma P, Cheng Z, Hou Z, Li C, Lin J (2015) Current advances in lanthanide ion (Ln3+)-based upconversion nanomaterials for drug delivery. Chem Soc Rev 44:1416. doi: 10.1039/C4CS00155A10.1039/C4CS00155A ↗
7. Chen D, Liu L, Huang P, Ding M, Zhong J, Ji Z (2015) Nd3+-sensitized Ho3+ single-band red upconversion luminescence in core–shell nanoarchitecture. J Phys Chem Lett 6:2833. doi: 10.1021/acs.jpclett.5b0118010.1021/acs.jpclett.5b01180 ↗
8. Chen D, Chen Y, Lu H, Ji Z (2014) A bifunctional Cr/Yb/Tm:Ca3Ga2Ge3O12 phosphor with near-infrared long-lasting phosphorescence and upconversion luminescence. Inorg Chem 53:8638. doi: 10.1021/ic501238u10.1021/ic501238u ↗
9. Gai S, Li C, Yang P, Lin J (2013) Recent progress in rare earth micro/nanocrystals: soft chemical synthesis, luminescent properties, and biomedical applications. Chem Rev 114:2343. doi: 10.1021/cr400159410.1021/cr4001594 ↗
10. Dai Y, Xiao H, Liu J et al (2013) In Vivo multimodality imaging and cancer therapy by near-infrared light-triggered trans-platinum pro-drug-conjugated upconverison nanoparticles. J Am Chem Soc 135:18920. doi: 10.1021/ja410028q10.1021/ja410028q ↗
11. Dai Y, Ma P, Cheng Z et al (2012) Up-conversion cell imaging and pH-induced thermally controlled drug release from NaYF4:Yb3+/Er3+@Hydrogel core–shell hybrid microspheres. ACS Nano 6:3327. doi: 10.1021/nn300303q10.1021/nn300303q ↗
12. Liu Q, Sun Y, Yang T, Feng W, Li C, Li F (2011) Sub-10 nm hexagonal lanthanide-doped NaLuF4 upconversion nanocrystals for sensitive bioimaging in Vivo. J Am Chem Soc 133:17122. doi: 10.1021/ja207078s10.1021/ja207078s ↗
13. Wong H-T, Vetrone F, Naccache R, Chan HLW, Hao J, Capobianco JA (2011) Water dispersible ultra-small multifunctional KGdF4:Tm3 + , Yb3 + nanoparticles with near-infrared to near-infrared upconversion. J Mater Chem 21:16589. doi: 10.1039/c1jm12796a10.1039/c1jm12796a ↗
14. Chen G, Ohulchanskyy TY, Kumar R, Ågren H, Prasad PN (2010) Ultrasmall monodisperse NaYF4:Yb3+/Tm3+ nanocrystals with enhanced near-infrared to near-infrared upconversion photoluminescence. ACS Nano 4:3163. doi: 10.1021/nn100457j10.1021/nn100457j ↗
15. Chen G, Qiu H, Fan R et al (2012) Lanthanide-doped ultrasmall yttrium fluoride nanoparticles with enhanced multicolor upconversion photoluminescence. J Mater Chem 22:20190. doi: 10.1039/C2JM32298F10.1039/c2jm32298f ↗
16. Chen G, Ohulchanskyy TY, Law WC, Agren H, Prasad PN (2011) Monodisperse NaYbF4:Tm3+/NaGdF4 core/shell nanocrystals with near-infrared to near-infrared upconversion photoluminescence and magnetic resonance properties. Nanoscale 3:2003. doi: 10.1039/C0NR01018A10.1039/c0nr01018a ↗
17. Longmire M, Choyke PL, Kobayashi H (2008) Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats. Nanomedicine 3:703. doi: 10.2217/17435889.3.5.70310.2217/17435889.3.5.703 ↗
18. Huang X (2015) Dual-model upconversion luminescence from NaGdF4:Nd/Yb/Tm@NaGdF4:Eu/Tb core–shell nanoparticles. J Alloys Compd 628:240. doi: 10.1016/j.jallcom.2014.12.17810.1016/j.jallcom.2014.12.178 ↗
19. Gao D, Zhang X, Zheng H, Shi P, Li L, Ling Y (2013) Codopant ion-induced tunable upconversion emission in β-NaYF4:Yb3+/Tm3+ nanorods. Dalton Trans 42:1834. doi: 10.1039/C2DT31814H10.1039/C2DT31814H ↗
20. T Jiang, W Qin, J Zhou (2014) J Alloys Compd 593:79. doi: 10.1016/j.jallcom.2014.01.04810.1016/j.jallcom.2014.01.048 ↗
21. Chen D, Huang P (2014) Highly intense upconversion luminescence in Yb/Er:NaGdF4@NaYF4 core-shell nanocrystals with complete shell enclosure of the core. Dalton Trans 43:11299. doi: 10.1039/C4DT01237B10.1039/c4dt01237b ↗
22. Chen D, Wan Z, Zhou Y et al (2015) Dual-phase glass ceramic: structure, dual-modal luminescence, and temperature sensing behaviors. ACS Appl Mater Interfaces 7:19484. doi: 10.1021/acsami.5b0603610.1021/acsami.5b06036 ↗
23. Li C, Lin J (2010) Rare earth fluoride nano-/microcrystals: synthesis, surface modification and application. J Mater Chem 20:6831. doi: 10.1039/C0JM00031K10.1039/c0jm00031k ↗
24. Gai S, Yang P, Li C et al (2010) Synthesis of magnetic, up-conversion luminescent, and mesoporous core–shell-structured nanocomposites as drug carriers. Adv Funct Mater 20:1166. doi: 10.1002/adfm.20090227410.1002/adfm.200902274 ↗
25. Zhuang J, Yang X, Fu J et al (2013) Monodispersed β-NaYF4 mesocrystals. In Situ ion exchange and multicolor up- and down-conversions. Cryst Growth Des 13:2292. doi: 10.1021/cg301751c10.1021/cg301751c ↗
26. Gao D, Tian D, Xiao G, Chong B, Yu G, Pang Q (2015) Up/down conversion switching by adjusting the pulse width of red laser beams in LaF3:Tm3+ nanocrystals. Opt Lett 40:3580. doi: 10.1364/OL.40.00358010.1364/OL.40.003580 ↗
27. Ma J, Huang P, He M et al (2012) Folic acid-conjugated LaF3:Yb, Tm@SiO2 nanoprobes for targeting dual-modality imaging of upconversion luminescence and X-ray computed tomography. J Phys Chem B 116:14062. doi: 10.1021/jp309059u10.1021/jp309059u ↗
28. Sivakumar S, Boyer J-C, Bovero E, van Veggel FCJM (2009) Up-conversion of 980 nm light into white light from sol–gel derived thin film made with new combinations of LaF3:Ln3+ nanoparticles. J Mater Chem 19:2392. doi: 10.1039/b818397j10.1039/b818397j ↗
29. Bai X, Li D, Liu Q, Dong B, Xu S, Song H (2012) Concentration-controlled emission in LaF3:Yb3+/Tm3+ nanocrystals: switching from UV to NIR regions. J Mater Chem 22:24698. doi: 10.1039/C2JM35403A10.1039/c2jm35403a ↗
30. Li F, Li C, Liu X et al (2013) Microwave-assisted synthesis and up-down conversion luminescent properties of multicolor hydrophilic LaF3:Ln3+ nanocrystals. Dalton Trans 42:2015. doi: 10.1039/C2DT32295A10.1039/C2DT32295A ↗
31. Bao L, Li Z, Tao Q, Xie J, Mei Y, Xiong Y (2013) Controlled synthesis of uniform LaF3 polyhedrons, nanorods and nanoplates using NaOH and ligands. Nanotechnology 24:145604. doi: 10.1088/0957-4484/24/14/14560410.1088/0957-4484/24/14/145604 ↗
32. Huang X (2015) Giant enhancement of upconversion emission in (NaYF4:Nd3+/Yb3+/Ho3+)/(NaYF4:Nd3+/Yb3+) core/shell nanoparticles excited at 808 nm. Opt Lett 40:3599. doi: 10.1364/OL.40.00359910.1364/OL.40.003599 ↗
33. Li D, Shao Q, Dong Y, Jiang J (2014) Temperature sensitivity and stability of NaYF4:Yb3+, Er3+ core-only and core–shell upconversion nanoparticles. J Alloys Compd 617:1. doi: 10.1016/j.jallcom.2014.07.19710.1016/j.jallcom.2014.07.197 ↗
34. Huang X, Lin J (2015) Active-core/active-shell nanostructured design: an effective strategy to enhance Nd3+/Yb3+ cascade sensitized upconversion luminescence in lanthanide-doped nanoparticles. J Mater Chem C 3:7652. doi: 10.1039/C5TC01438G10.1039/C5TC01438G ↗
35. Wang M, Mi C, Zhang Y et al (2009) NIR-responsive silica-coated NaYbF4:Er/Tm/Ho upconversion fluorescent nanoparticles with tunable emission colors and their applications in immunolabeling and fluorescent imaging of cancer cells. J Phys Chem C 113:19021. doi: 10.1021/jp906394z10.1021/jp906394z ↗
36. Chen D, Wan Z, Zhou Y et al (2015) Bulk glass ceramics containing Yb3+/Er3+: β-NaGdF4 nanocrystals: phase-separation-controlled crystallization, optical spectroscopy and upconverted temperature sensing behavior. J Alloys Compd 638:21. doi: 10.1016/j.jallcom.2015.02.17010.1016/j.jallcom.2015.02.170 ↗
37. Huang X, Han S, Huang W, Liu X (2013) Enhancing solar cell efficiency: the search for luminescent materials as spectral converters. Chem Soc Rev 42:173. doi: 10.1039/C2CS35288E10.1039/C2CS35288E ↗
38. Li X, Wang R, Zhang F, Zhao D (2014) Engineering homogeneous doping in single nanoparticle to enhance upconversion efficiency. Nano Lett 14:3634. doi: 10.1021/nl501366x10.1021/nl501366x ↗
39. Ding M, Ni Y, Song Y et al (2015) Li+ ions doping core–shell nanostructures: an approach to significantly enhance upconversion luminescence of lanthanide-doped nanocrystals. J Alloys Compd 623:42. doi: 10.1016/j.jallcom.2014.10.08910.1016/j.jallcom.2014.10.089 ↗
40. Mai H-X, Zhang Y-W, Sun L-D, Yan C-H (2007) Highly efficient multicolor up-conversion emissions and their mechanisms of monodisperse NaYF4:Yb, Er core and core/shell-structured nanocrystals. J Phys Chem C 111:13721. doi: 10.1021/jp073920d10.1021/jp073920d ↗
41. Johnson NJJ, Korinek A, Dong C, van Veggel FCJM (2012) Self-focusing by ostwald ripening: a strategy for layer-by-layer epitaxial growth on upconverting nanocrystals. J Am Chem Soc 134:11068. doi: 10.1021/ja302717u10.1021/ja302717u ↗
42. Dong H, Sun L-D, Wang Y-F et al (2015) Efficient tailoring of upconversion selectivity by engineering local structure of lanthanides in NaxREF3+x nanocrystals. J Am Chem Soc 137:6569. doi: 10.1021/jacs.5b0171810.1021/jacs.5b01718 ↗
43. Zhang F, Shi Q, Zhang Y et al (2011) Fluorescence upconversion microbarcodes for multiplexed biological detection: nucleic acid encoding. Adv Mater 23:3775. doi: 10.1002/adma.20110186810.1002/adma.201101868 ↗
44. Ren G, Zeng S, Hao J (2011) Tunable multicolor upconversion emissions and paramagnetic property of monodispersed bifunctional lanthanide-doped NaGdF4 nanorods. J Phys Chem C 115:20141. doi: 10.1021/jp206452910.1021/jp2064529 ↗
45. Boyer J-C, van Veggel FCJM (2010) Absolute quantum yield measurements of colloidal NaYF4:Er3 + , Yb3 + upconverting nanoparticles. Nanoscale 2:1417. doi: 10.1039/C0NR00253D10.1039/c0nr00253d ↗
46. Zhang F, Che R, Li X et al (2012) Direct imaging the upconversion nanocrystal core/shell structure at the subnanometer level: shell thickness dependence in upconverting optical properties. Nano Lett 12:2852. doi: 10.1021/nl300421n10.1021/nl300421n ↗