journal article·2017-02

Blending PLLA/tannin-grafted PCL fiber membrane for skin tissue engineering

Suchen Jiang, Ping Song, Huiling Guo, Xue Zhang, Yajun Ren, Huanchao Liu, Xiaofeng Song, Mingming Kong

Journal of Materials Science· Volume 52· Issue 3
Publisher page

Abstract

To create novel materials of skin tissue engineering, the blends of tannin-grafted poly(ɛ-caprolactone) (TA-g-PCL) and poly(l-lactic acid) (PLLA) have been prepared by electrospinning, and their corresponding characteristics are evaluated such as morphology, FTIR, thermodynamics, mechanics, wettability, as well as biocompatibility. TA-g-PCL and PLLA can be well blended to make smooth fibers, and fibrous diameter turns thinner with blending TA-g-PCL. At 15 wt%, the fibrous membrane shows higher tensile strength and elongation at a break than the other samples due to its best crystallinity. Membranous wettability drops with blending TA-g-PCL, but it increases sharply after incorporating PF108. At the same time, PLLA/TA-g-PCL fiber membrane is biocompatible. The biodegradable PLLA/TA-g-PLLA membrane is a promising candidate as skin tissue engineering.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · biodegradable polymer synthesis and properties · Silk-based biomaterials and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (35)

Show source-provided references
1. Agarwal S, Wendorff JH, Greiner A (2008) Use of electrospinning technique for biomedical applications. Polymer 49:5603–562110.1016/j.polymer.2008.09.014 ↗
2. Wang ZG, Wan LS, Liu ZM, Huang XJ, Xu ZK (2009) Enzyme immobilization on electrospun polymer nanofibers: an overview. J Mol Catal B 56:189–19510.1016/j.molcatb.2008.05.005 ↗
3. Smith LA, Ma PX (2004) Nano-fibrous scaffolds for tissue engineering. Colloid Surf B 39:125–13110.1016/j.colsurfb.2003.12.004 ↗
4. Li WJ, Laurencin CT, Caterson EJ, Tuan RS, Ko FK (2002) Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J Biomed Mater Res 60:613–62110.1002/jbm.10167 ↗
5. Zeng J, Xu X, Chen X, Liang Q, Bian X, Yang L, Jing X (2003) Biodegradable electrospun fibers for drug delivery. J Control Release 92(3):227–23110.1016/S0168-3659(03)00372-9 ↗
6. Zong X, Ran S, Fang D, Hsiao BS, Chu B (2003) Control of structure, morphology and property in electrospun poly(glycolide-co-lactide) non-woven membranes via post-draw treatments. Polymer 44(17):4959–496710.1016/S0032-3861(03)00464-6 ↗
7. Zeng J, Chen X, Liang Q, Xu X, Jing X (2004) Enzymatic degradation of poly(l-lactide) and poly(ε-caprolactone) electrospun fibers. Macromol Biosci 4(12):1118–112510.1002/mabi.200400092 ↗
8. Kim K, Luu YK, Chang C, Fang D, Hsiao BS, Chu B, Hadjiargyrou M (2004) Incorporation and controlled release of a hydrophilic antibiotic using poly(lactide-co-glycolide)-based electrospun nanofibrous scaffolds. J Control Release 98(1):47–5610.1016/j.jconrel.2004.04.009 ↗
9. Li AD, Sun ZZ, Zhou M, Xu XX, Ma JY, Zheng W, Zhou HM, Li L, Zheng YF (2013) Electrospun Chitosan-graft-PLGA nanofibres with significantly enhanced hydrophilicity and improved mechanical property. Colloids Surf B 102:674–68110.1016/j.colsurfb.2012.09.035 ↗
10. Meng ZX, Zheng W, Li L, Zheng YF (2011) Fabrication, characterization and in vitro drug release behavior of electrospun PLGA/chitosan nanofibrous scaffold. Mater Chem Phys 125(3):606–61110.1016/j.matchemphys.2010.10.010 ↗
11. Chong EJ, Phan TT, Lim IJ, Zhang YZ, Bay BH, Ramakrishna S, Lim CT (2007) Evaluation of electrospun PCL/gelatin nanofibrous scaffold for wound healing and layered dermal reconstitution. Acta Biomater 3(3):321–33010.1016/j.actbio.2007.01.002 ↗
12. Li JS, Li Y, Li L, Mak AFT, Ko F, Qin L (2009) Preparation and biodegradation of electrospun PLLA/keratin nonwoven fibrous membrane. Polym Degrad Stab 94:1800–180710.1016/j.polymdegradstab.2009.06.004 ↗
13. Jose MV, Thomas V, Dean DR, Nyairo E (2009) Fabrication and characterization of aligned nanofibrous PLGA/Collagen blends as bone tissue scaffolds. Polymer 50:3778–378510.1016/j.polymer.2009.05.035 ↗
14. Meng ZX, Zheng W, Li L, Zheng YF (2010) Fabrication and characterization of three-dimensional nanofiber membrance of PCL–MWCNTs by electrospinning. Mater Sci Eng 30:1014–102110.1016/j.msec.2010.05.003 ↗
15. Duan UY, Jia J, Wang SH, Yan W, Jin L, Wang ZY (2007) Preparation of antimicrobial poly(ɛ-caprolactone) electrospun nanofibers containing silver-loaded zirconium phosphate nanoparticles. J Appl Polym Sci 106(2):1208–121410.1002/app.26786 ↗
16. Chen KS, Hsiao YC, Kuo DY, Choua MC, Chud SC, Hsieh YS, Lin TH (2009) Tannic acid-induced apoptosis and -enhanced sensitivity to arsenic trioxide in human leukemia HL-60 cells. Leuk Res 33(2):297–30710.1016/j.leukres.2008.08.006 ↗
17. Sakagami H, Jiang Y, Kusama K, Atsumi T, Ueha T, Toguchi M, Iwakura I, Satoh K, Ito H, Hatano T, Yoshida T (2000) Cytotoxic activity of hydrolyzable tannins against human oral tumor cell lines—a possible mechanism. Phytomedicine 7(1):39–4710.1016/S0944-7113(00)80020-3 ↗
18. Tikoo K, Sane MS, Gupta C (2011) Tannic acid ameliorates doxorubicin-induced cardiotoxicity and potentiates its anti-cancer activity: potential role of tannins in cancer chemotherapy. Toxicol Appl Pharmacol 251(3):191–20010.1016/j.taap.2010.12.012 ↗
19. Kozlovskaya V, Zavgorodnya O, Chen Y, Ellis K, Tse HM, Cui W, Thompson JA, Kharlampieva E (2012) Ultrathin polymeric coatings based on hydrogen-bonded polyphenol for protection of pancreatic islet cells. Adv Funct Mater 22(16):3389–339810.1002/adfm.201200138 ↗
20. Chen J, Kozlovskaya V, Goins A, Campos-Gomez J, Saeed M, Kharlampieva E (2013) Biocompatible shaped particles from dried multilayer polymer capsules. Biomacromolecules 14(11):3830–384110.1021/bm4008666 ↗
21. Dierendonck M, Fierens K, De Rycke R, Lybaert L, Maji S, Zhang Z, Zhang Q, Hoogenboom R, Lambrecht BN, Grooten J, Remon JP, De Koker S, De Geest B (2014) Nanoporous hydrogen bonded polymeric microparticles: facile and economic production of cross presentation promoting vaccine carriers. Adv Funct Mater 24(29):4634–464410.1002/adfm.201400763 ↗
22. Park JH, Yang SH, Lee J, Ko EH, Hong D, Choi IS (2014) Nanocoating of single cells: from maintenance of cell viability to manipulation of cellular activities. Adv Mater 26(13):2001–201010.1002/adma.201304568 ↗
23. Zhuk I, Jariwala F, Attygalle AB, Wu Y, Libera MR, Sukhishvili SA (2014) Self-defensive layer-by-Layer films with bacteria-triggered antibiotic release. ACS Nano 8(8):7733–774510.1021/nn500674g ↗
24. Song P, Jiang SC, Ren YJ, Zhang X, Qiao TK, Song XF, Liu QM, Chen XS (2016) Synthesis and characterization of tannin grafted polycaprolactone. J Colloid Interface Sci 479:160–16410.1016/j.jcis.2016.06.056 ↗
25. Li HT, Qiao TK, Song P, Guo HL, Song XF, Zhang BC, Chen XS (2015) Star-shaped PCL/PLLA blended fiber membrane via electrospinning. J Biomater Sci Polym Ed 26(7):420–43210.1080/09205063.2015.1015865 ↗
26. Qiao TK, Song P, Guo HL, Song XF, Zhang BC, Chen XS (2016) Reinforced electrospun PLLA fiber membrane via chemical crosslinking. Eur Polym J 74:101–10810.1016/j.eurpolymj.2015.11.012 ↗
27. Zhou H, Du T, Shen Y, Wang Z, Zheng Y, Haapasalo M (2015) In vitro cytotoxicity of calcium silicate-containing endodontic sealers. J Endod 41:56–6110.1016/j.joen.2014.09.012 ↗
28. Deitzel JM, Kleinmeyer J, Harris D, Tan NCB (2001) The effect of processing variables on the morphology of electrospun nanofibers and textiles. Polymer 42:261–27210.1016/S0032-3861(00)00250-0 ↗
29. Demir MM, Yilgor I, Yilgor E, Erman B (2002) Electrospinning of polyurethane fibers. Polymer 43:3303–330910.1016/S0032-3861(02)00136-2 ↗
30. Prabhakaran MP, Venugopal J, Ramakrishna S (2009) Electrospun nanostructured scaffolds for bone tissue engineering. Acta Biomater 5:2884–289310.1016/j.actbio.2009.05.007 ↗
31. Dell’Erba R, Groeninckx G, Maglio G, Malinconico M, Migliozzi A (2001) Immiscible polymer blends of semicrystalline biocompatible components: thermal properties and phase morphology analysis of PLLA/PCL blends. Polymer 42(18):7831–784010.1016/S0032-3861(01)00269-5 ↗
32. Jaiswal AK, Chhabra H, Soni VP, Bellare JR (2013) Enhanced mechanical strength and biocompatibility of electrospun polycaprolactone–gelatin scaffold with surface deposited nano-hydroxyapatite. Mater Sci Eng 33:2376–238510.1016/j.msec.2013.02.003 ↗
33. Li HT, Song P, Qiao TK, Cui QQ, Song XF, Zhang BC (2016) A quaternary composite fiber membrane for guided tissue regeneration. Polym Adv Technol 27(2):178–18410.1002/pat.3616 ↗
34. Khang G, Choee JH, Rhee JM, Lee HB (2002) Interaction of different types of cells on physicochemically treated poly(l-lactide-co-glycolide) surfaces. J Appl Polym Sci 85:1253–126210.1002/app.10680 ↗
35. Yoo HS, Kim TG, Park TG (2009) Surface-functionalized electrospun nanofibers for tissue engineering and drug delivery. Adv Drug Deliv Rev 61:1033–104210.1016/j.addr.2009.07.007 ↗