Electrophoretic deposition of hydroxyapatite and hydroxyapatite–alginate on rapid prototyped 3D Ti6Al4V scaffolds
Source abstract
Abstract
The advantage of using bioceramic particles coated on porous three-dimensional structures is still unexplored in the purpose of improving the osteoinduction of hybrid metallic scaffold implants in vivo. In this study, we evaluate electrophoretic deposition (EPD) to coat porous Ti6Al4V scaffolds with hydroxyapatite (HA). Scaffolds were shaped in different open structures with a horizontal shift in fiber stacking. They were produced using three-dimensional fiber deposition method and were coated by EPD with HA powder (d10 = 1.7, d50 = 5.7 and d90 = 18 µm) suspended in ethanol or butanol at different concentration, DC voltage, and time. A composite HA–alginate was also used to coat the scaffolds. Alginate was used as a binder, and the coating properties (homogeneity, thickness, cracks, continuity, etc.) were compared to coatings obtained from pure HA suspensions. Voltage and time of deposition effects were studied between 10 and 140 V and 10 and 120 s, respectively. Coating thickness and density with respect to the depth of the porous structure were studied by observing cross sections using scanning electron microscopy and image processing analysis. HA–alginate combination resulted in a homogeneous and deeper dense layer of HA. This work also points to the characteristics of HA–alginate composite as a superior alternative to pure HA coating which needs an appropriate thermal treatment for adequate substrate adhesion.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Electrophoretic Deposition in Materials Science · Advanced Photocatalysis Techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (28)
Show source-provided references
1. Luyten J, Thijs I, Ravelingien M, Mullens S (2011) Bone engineering with porous ceramics and metals. Adv Eng Mater 13:1002–1007. doi: 10.1002/adem.20110001610.1002/adem.201100016 ↗
2. Navarro M, Michiardi A, Castaño O, Planell JA (2008) Biomaterials in orthopaedics. J R Soc Interface 5:1137–1158. doi: 10.1098/rsif.2008.015110.1098/rsif.2008.0151 ↗
3. Cadosch D, Chan E, Gautschi OP, Filgueira L (2009) Metal is not inert: Role of metal ions released by biocorrosion in aseptic loosening–current concepts. J Biomed Mater Res A 91:1252–1262. doi: 10.1002/jbm.a.3262510.1002/jbm.a.32625 ↗
4. Barradas AMC, Yuan H, Van Blitterswijk CA, Habibovic P (2011) Osteoinductive biomaterials : current knowledge of properties, experimental models and biological mechanisms. Eur Cell Mater 21:407–42910.22203/eCM.v021a31 ↗
5. Zhang Q, Leng Y, Xin R (2005) A comparative study of electrochemical deposition and biomimetic deposition of calcium phosphate on porous titanium. Biomaterials 26:2857–2865. doi: 10.1016/j.biomaterials.2004.08.01610.1016/j.biomaterials.2004.08.016 ↗
6. Yang Y, Kim K-H, Ong JL (2005) A review on calcium phosphate coatings produced using a sputtering process–an alternative to plasma spraying. Biomaterials 26:327–337. doi: 10.1016/j.biomaterials.2004.02.02910.1016/j.biomaterials.2004.02.029 ↗
7. Jiang G, Shi D (1998) Coating of hydroxyapatite on highly porous Al2O3 substrate for bone substitutes. J Biomed Mater Res 43:77–81. doi: 10.1002/(SICI)1097-4636(199821)43:1<77::AID-JBM9>3.0.CO;2-J10.1002/(SICI)1097-4636(199821)43:1<77::AID-JBM9>3.0.CO;2-J ↗
8. Braem A, Chaudhari A, Vivan Cardoso M et al (2014) Peri- and intra-implant bone response to microporous Ti coatings with surface modification. Acta Biomater 10:986–995. doi: 10.1016/j.actbio.2013.10.01710.1016/j.actbio.2013.10.017 ↗
9. Yu P, Lu F, Zhu W et al (2014) Bio-inspired citrate functionalized apatite coating on rapid prototyped titanium scaffold. Appl Surf Sci 313:947–953. doi: 10.1016/j.apsusc.2014.06.11310.1016/j.apsusc.2014.06.113 ↗
10. Habibovic P, Barre F, Van Blitterswijk CA et al (2002) Biomimetic hydroxyapatite coating on metal implants. J Am Ceram Soc 85:517–522. doi: 10.1111/j.1151-2916.2002.tb00126.x10.1111/j.1151-2916.2002.tb00126.x ↗
11. Chai YC, Truscello S, Van Bael S et al (2011) Perfusion electrodeposition of calcium phosphate on additive manufactured titanium scaffolds for bone engineering. Acta Biomater 7:2310–2319. doi: 10.1016/j.actbio.2010.12.03210.1016/j.actbio.2010.12.032 ↗
12. Lopez-Heredia MA, Sohier J, Gaillard C et al (2008) Rapid prototyped porous titanium coated with calcium phosphate as a scaffold for bone tissue engineering. Biomaterials 29:2608–2615. doi: 10.1016/j.biomaterials.2008.02.02110.1016/j.biomaterials.2008.02.021 ↗
13. Chen Q, Cordero-Arias L, Roether JA et al (2013) Alginate/Bioglass® composite coatings on stainless steel deposited by direct current and alternating current electrophoretic deposition. Surf Coat Technol 233:49–56. doi: 10.1016/j.surfcoat.2013.01.04210.1016/j.surfcoat.2013.01.042 ↗
14. Seuss S, Lehmann M, Boccaccini AR (2014) Alternating current electrophoretic deposition of antibacterial bioactive glass-chitosan composite coatings. Int J Mol Sci 15:12231–12242. doi: 10.3390/ijms15071223110.3390/ijms150712231 ↗
15. Boccaccini AR, Keim S, Ma R et al (2010) Electrophoretic deposition of biomaterials. J R Soc Interface 7:S581–S613. doi: 10.1098/rsif.2010.0156.focus10.1098/rsif.2010.0156.focus ↗
16. Corni I, Ryan MP, Boccaccini AR (2008) Electrophoretic deposition: from traditional ceramics to nanotechnology. J Eur Ceram Soc 28:1353–1367. doi: 10.1016/j.jeurceramsoc.2007.12.01110.1016/j.jeurceramsoc.2007.12.011 ↗
17. Boccaccini AR, Roether JA, Thomas BJC et al (2006) The electrophoretic deposition of inorganic nanoscaled materials. J Ceram Soc Jpn 114:1–14. doi: 10.2109/jcersj.114.110.2109/jcersj.114.1 ↗
18. Boccaccini AR, Chicatun F, Cho J et al (2007) Carbon nanotube coatings on bioglass-based tissue engineering scaffolds. Adv Funct Mater 17:2815–2822. doi: 10.1002/adfm.20060088710.1002/adfm.200600887 ↗
19. Meng D, Ioannou J, Boccaccini AR (2009) Bioglass-based scaffolds with carbon nanotube coating for bone tissue engineering. J Mater Sci Mater Med 20:2139–2144. doi: 10.1007/s10856-009-3770-910.1007/s10856-009-3770-9 ↗
20. Li JP, de Wijn JR, Van Blitterswijk CA, de Groot K (2006) Porous Ti6Al4V scaffold directly fabricating by rapid prototyping: preparation and in vitro experiment. Biomaterials 27:1223–1235. doi: 10.1016/j.biomaterials.2005.08.03310.1016/j.biomaterials.2005.08.033 ↗
21. Dellinger JG, Cesarano J III, Jamison RD (2007) Robotic deposition of model hydroxyapatite scaffolds with multiple architectures and multiscale porosity for bone tissue engineering. J Biomed Mater Res A 82:383–394. doi: 10.1002/jbm.a.3107210.1002/jbm.a.31072 ↗
22. Ravelingien M (2010) Development of titanium bone scaffolds with drug delivery system. Dissertation, Ghent University
23. Ozhukil Kollath V, Chen Q, Closset R et al (2013) AC vs. DC electrophoretic deposition of hydroxyapatite on titanium. J Eur Ceram Soc. doi: 10.1016/j.jeurceramsoc.2013.04.030
24. Hamaker HC, Verwey EJW (1940) The role of the forces between the particles in electrodeposition and other phenomena. Trans Faraday Soc 35:180–18510.1039/TF9403500180 ↗
25. Van der Biest OO, Vandeperre LJ (1999) Electrophoretic deposition of materials. Annu Rev Mater Sci 29:327–352. doi: 10.1146/annurev.matsci.29.1.32710.1146/annurev.matsci.29.1.327 ↗
26. Wang G, Sarkar P, Nicholson PS (1997) Influence of acidity on the electrostatic stability of alumina suspensions in ethanol. J Am Ceram Soc 80:965–972. doi: 10.1111/j.1151-2916.1997.tb02928.x10.1111/j.1151-2916.1997.tb02928.x ↗
27. Stoppel WL, White JC, Horava SD et al (2011) Transport of biological molecules in surfactant-alginate composite hydrogels. Acta Biomater 7:3988–3998. doi: 10.1016/j.actbio.2011.07.00910.1016/j.actbio.2011.07.009 ↗
28. Cheong M, Zhitomirsky I (2008) Electrodeposition of alginic acid and composite films. Colloids Surfaces A Physicochem Eng Asp 328:73–78. doi: 10.1016/j.colsurfa.2008.06.01910.1016/j.colsurfa.2008.06.019 ↗