Toward improvements for carrying capacity of the cyclodextrin-based nanosponges: recent progress from a material and drug delivery
Source abstract
Abstract
Cyclodextrins are a type of natural materials that can be used in the pharmaceutical industry. Cyclodextrins are safe, biodegradable, with the multifunctional property as they can encapsulate both hydrophilic and hydrophobic drugs. Additionally, they can overcome challenges associated with drug toxicity and enhancing the solubility of the insoluble drugs; thus, cyclodextrins are effective carriers in loading tiny molecules. Moreover, the synthesis of nanosponges (NPs) systems can enhance the drug encapsulation in cyclodextrin cavities to control the rate of drug released. Cyclodextrin can contain the drug molecules to form a clathrate; cyclodextrin-based NPs can maintain a high loading capacity of various small molecules for drug delivery. This review presents a general overview of the current research progress and the applications of cyclodextrin-based NPs for drug delivery in the past two decades.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Drug Solubulity and Delivery Systems · Advanced Drug Delivery Systems · Nanoparticle-Based Drug Delivery
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
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