Fe3O4@GO nanocomposite-based electrochemical platform for the measurement of bovine serum albumin as model protein for the clinical detection of biomolecules
Source abstract
Abstract
Iron oxide/graphene oxide-modified glassy carbon electrode (Fe3O4@GO/GCE) interface was fabricated by in situ wet chemical method followed by morphological and structural analysis through FESEM and TEM, for the electrochemical detection of bovine serum albumin (BSA). Electrochemical behavior of designed interface was studied by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and amperometry; a significant increase in BSA electrodeposition by fabricated (Fe3O4@GO/GCE) interface indicated an enhanced adsorptive interaction toward dispersed BSA, pertaining to its modified morphology having embedded Fe3O4NPs over GO surface as shown by FESEM and TEM results. Thus, electrocatalytic potential of system was decreased as specified by reduced current flow. The electrochemical responses were linearly dependent on the BSA concentration in the range of 10–18-10–1g mL−1with the limit of detection of 0.46 × 10–19g mL−1. It is proposed that designed interfaces can be an advantageous platform to develop biosensors because of having a high potential to detect clinically important biomolecules.Graphical abstract
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Electrochemical sensors and biosensors · Electrochemical Analysis and Applications · Advanced biosensing and bioanalysis techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (48)
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