Bio-physical investigation of calcium silicate biomaterials by green synthesis- osseous tissue regeneration
Source abstract
Abstract
CaSiO3wollastonite biomaterials were synthesized by hydrothermal approach in three different weight percentages of SiO2and CaO (CA—25:75, CB—50:50, and CC—75:25) extracted from silica sand and limestone. In vitro biological testing revealed the materials bioactivity in SBF and their antibacterial efficacy againstStreptococcus aureusandEscherichia coli. By direct contact with the L929 mouse fibroblast cell line, the cell viability against synthesized biomaterials was examined. These bio-properties were interlinked with the degradation rate of biomaterials in biofluid, which was observed under Tris–Hcl immersion. The regulated degradation of synthesized biomaterial simultaneously constrained the alkaline pH shift, which is beneficial for bioactivation and biocompatibility. It attained a compressive strength of 73 MPa without failure, which is equivalent to or higher than conventional bioglass and suitable for load-bearing sites. The synthesized biomaterials acquire excellent bioactivity, biocompatibility, and mechanical stability through controlled degradation versus bone apatite formation in a balanced manner, supported by porously fused structure.Graphical abstract
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Endodontics and Root Canal Treatments · Dental Implant Techniques and Outcomes
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (53)
Show source-provided references
1. I. Sheikh, Y. Dahman, Applications of nanobiomaterials in hard tissue engineering, in Biomaterials in hard tissue engineering. (Elsevier, Amsterdam, 2016), pp.33–6210.1016/B978-0-323-42862-0.00002-X ↗
2. C. Ning, L. Zhou, G. Tan, Fourth-generation biomedical materials. Mater. Today 19(1), 2–3 (2016)10.1016/j.mattod.2015.11.005 ↗
3. M.S. de Almeida, G.V. de Oliveira Fernandes, A.M. Oliveira, J.M. Granjeiro, Calcium silicate as a graft material for bone fractures: a systematic review. J. Int. Med. Res. 46(7), 2537–2548 (2018)10.1177/0300060518770940 ↗
4. E. Papynov, O. Shichalin, I. Buravlev, A. Belov, A. Portnyagin, V. Mayorov, E. Merkulov, T. Kaidalova, Y. Skurikhina, V. Turkutyukov, A. Fedorets, V. Apanasevich, CaSiO3-HAp structural bioceramic by sol-gel and SPS-RS techniques: Bacteria test assessment. J. Funct. Biomater. 11(2), 41 (2020)10.3390/jfb11020041 ↗
5. K. Prasad, O. Bazaka, M. Chua, M. Rochford, L. Fedrick, J. Spoor, R. Symes, M. Tieppo, C. Collins, A. Cao, D. Markwell, K. Ostrikov, K. Bazaka, Metallic biomaterials: current challenges and opportunities. Materials 10(8), 884 (2017)10.3390/ma10080884 ↗
6. S. Wang, L. Lu, C. Wang, C. Gao, X. Wang, Polymeric biomaterials for tissue engineering applications. Int. J. Polym. Sci. (2011). https://doi.org/10.1155/2011/18462310.1155/2011/184623 ↗
7. S. Punj, J. Singh, K. Singh, Ceramic biomaterials: properties, state of the art and future prospective. Ceram. Int. 47(20), 28059–28074 (2021)10.1016/j.ceramint.2021.06.238 ↗
8. J. Huang, S.M. Best, Ceramic biomaterials, in Tissue engineering using ceramics and polymers. (Elsevier, Amsterdam, 2007), pp.3–3110.1533/9781845693817.1.3 ↗
9. S. Wei, J.X. Ma, L. Xu, X.S. Gu, X.L. Ma, Biodegradable materials for bone defect repair. Mil. Med. Res. (2020). https://doi.org/10.1186/s40779-020-00280-10.1186/s40779-020-00280- ↗
10. Z. Zhang, H. Shao, T. Lin, Y. Zhang, J. He, L. Wang, 3D gel printing of porous calcium silicate scaffold for bone tissue engineering. J. Mater. Sci. (2019). https://doi.org/10.1007/s10853-019-03626-110.1007/s10853-019-03626-1 ↗
11. S. Palakurthy, K. Venu Gopal Reddy, R.K. Samudrala, P. Abdul Azeem, In vitro bioactivity and degradation behaviour of β-wollastonite derived from natural waste. Mater. Sci. Eng.: C 98, 109–117 (2019)10.1016/j.msec.2018.12.101 ↗
12. L.L. Hench, The story of bioglass. J. Mater. Sci.—Mater. Med. 17(11), 967–978 (2006)10.1007/s10856-006-0432-z ↗
13. L.A. Adams, E.R. Essien, E.E. Kaufmann, A new route to sol-gel crystalline wollastonite bioceramic. J. Asian Ceram. Soc. 6(2), 132–138 (2018)10.1080/21870764.2018.1480685 ↗
14. E.J. Nassar et al., Biomaterials and sol-gel process: a methodology for the preparation of functional materials, in Biomaterials science and engineering. (IntechOpen, London, 2011)
15. Y.X. Gan, A.H. Jayatissa, Z. Yu, X. Chen, M. Li, Hydrothermal synthesis of nanomaterials. J. Nanomater. (2020). https://doi.org/10.1155/2020/891701310.1155/2020/8917013 ↗
16. K. Lin, W. Zhai, S. Ni, J. Chang, Yi. Zeng, W. Qian, Study of the mechanical property and in vitro biocompatibility of CaSiO3 ceramics. Ceram. Int. 31(2), 323–326 (2005)10.1016/j.ceramint.2004.05.023 ↗
17. M.A. de la Casa-Lillo, P. Velásquez, P.N. De Aza, Influence of thermal treatment on the “in vitro” bioactivity of wollastonite materials. J. Mater. Sci.: Mater. Med. 22(4), 907–915 (2011)
18. K. Lin, C. Lin, Yi. Zeng, High mechanical strength bioactive wollastonite bioceramics sintered from nanofibers. RSC Adv. 6(17), 13867–13872 (2016)10.1039/C5RA26916D ↗
19. P. Kumar, B.S. Dehiya, A. Sindhu, R. Kumar, C.I. Pruncu, A. Yadav, Fabrication and characterization of silver nanorods incorporated calcium silicate scaffold using polymeric sponge replica technique. Mater. Des. 195, 109026 (2020)10.1016/j.matdes.2020.109026 ↗
20. Z. Du, H. Leng, L. Guo, Y. Huang, T. Zheng, Z. Zhao, X. Liu, X. Zhang, Q. Cai, X. Yang, Calcium silicate scaffolds promoting bone regeneration via the doping of Mg2+ or Mn2+ ion. Composites B 190, 107937 (2020)10.1016/j.compositesb.2020.107937 ↗
21. P. Srinath, P.A. Azeem, K.V. Reddy, V. Penugurti, B. Manavathi, Zirconia-containing wollastonite ceramics derived from bio waste resources for bone tissue engineering. Biomed. Mater. (2020). https://doi.org/10.1088/1748-605X/ab975d10.1088/1748-605X/ab975d ↗
22. G.G. dos Santos, L.Q. Vasconcelos, I.C. Barreto, F.B. Miguel, R.P. de Araújo, Wollastonite and tricalcium phosphate composites for bone regeneration. Res. Soc. Dev. 11(9), e12011931662 (2022)10.33448/rsd-v11i9.31662 ↗
23. K. Kazeli, I. Tsamesidis, A. Theocharidou, L. Malletzidou, J. Rhoades, G.K. Pouroutzidou, E. Likotrafiti, K. Chrissafis, T. Lialiaris, L. Papadopoulou, E. Kontonasaki, E. Lymperaki, Synthesis and characterization of novel calcium-silicate nanobioceramics with magnesium: effect of heat treatment on biological, physical and chemical properties. Ceramics 4, 628–651 (2021)10.3390/ceramics4040045 ↗
24. R. Lakshmi, V. Velmurugan, S. Sasikumar, Preparation and phase evolution of wollastonite by sol-gel combustion method using sucrose as the fuel. Combust. Sci. Technol. 185(12), 1777–1785 (2013)10.1080/00102202.2013.835308 ↗
25. P.N. Jagadale, S.R. Kulal, M.G. Joshi, P.P. Jagtap, S.M. Khetre, S.R. Bamane, Synthesis and characterization of nanostructured CaSiO3 biomaterial. Mater. Sci.- Pol. 31(2), 269–275 (2013)10.2478/s13536-012-0099-8 ↗
26. P. Barpanda, N. Recham, J.-N. Chotard, K. Djellab, W. Walker, M. Armand, J.-M. Tarascon, Structure and electrochemical properties of novel mixed Li(Fe1−x Mx)SO4F (M = Co, Ni, Mn) phases fabricated by low temperature ionothermal synthesis. J. Mater. Chem. 20(9), 1659 (2010)10.1039/b922063a ↗
27. K. Li, C. Hall, A. Hamilton, Effect of silica particle size on the formation of calcium silicate hydrate [C-S-H] using thermal analysis. Thermochim. Acta 672, 142–149 (2019)10.1016/j.tca.2018.09.003 ↗
28. E. Tamjid, R. Bagheri, M. Vossoughi, A. Simchi, Effect of particle size on the in vitro bioactivity, hydrophilicity and mechanical properties of bioactive glass-reinforced polycaprolactone composites. Mater. Sci. Eng. C 31(7), 1526–1533 (2011)10.1016/j.msec.2011.06.013 ↗
29. G.B. Tomar, J.R. Dave, S.T. Mhaske, S. Mamidwar, P.K. Makar, Application of biomaterials in bone tissue engineering, in Functional bionanomaterials, biotechnology in the life science. (Springer, Cham, 2020), pp.209–25010.1007/978-3-030-41464-1_10 ↗
30. S.N. Ishmah, M.D. Permana, M.L. Firdaus, D.R. Eddy, Extraction of silica from Bengkulu beach sand using alkali fusion method. Pendipa J. Sci. Educ. 4(2), 1–5 (2020)10.33369/pendipa.4.2.1-5 ↗
31. M. Samari, F. Ridha, V. Manovic, A. Macchi, E.J. Anthony, Direct capture of carbon dioxide from air via lime-based sorbents. Mitig. Adapt. Strateg. Glob. Change 25, 25–41 (2019)10.1007/s11027-019-9845-0 ↗
32. A.C. Janini, G.F. Bombarda, L.E. Pelepenko, M.A. Marciano, Antimicrobial activity of calcium silicate-based dental materials: a literature review. Antibiotics 10(7), 865 (2021)10.3390/antibiotics10070865 ↗
33. G.C. Wang, Z.F. Lu, H. Zreiqat, Bioceramics for skeletal bone regeneration, in Bone substitute biomaterials. (Elsevier, Amsterdam, 2014), pp.180–21610.1533/9780857099037.2.180 ↗
34. T. Yokoyama, Basic properties and measuring methods of nanoparticles, in Nanoparticle technology handbook. (Elsevier, Amsterdam, 2018), pp.3–47
35. R. Alias, The effects of sintering temperature variations on microstructure changes of LTCC substrate, in Sintering of ceramics—new emerging technique. (InTech, London, 2012)
36. E. Fiume, G. Magnaterra, A. Rahdar, E. Verne, F. Baino, HAp for biomedical applications: a short overview. Ceramics 4, 542–563 (2021)10.3390/ceramics4040039 ↗
37. M. Balouiri, M. Sadiki, S.K. Ibnsouda, Methods for in vitro evaluating antimicrobial activity: a review. J. Pharm. Anal. 6(2), 71–79 (2016)10.1016/j.jpha.2015.11.005 ↗
38. I.M. Hamouda, Current perspectives of nanoparticles in medical and dental biomaterials. J. Biomed. Res. 26(3), 143 (2012)10.7555/JBR.26.20120027 ↗
39. S. Ramesh, C.Y. Tan, M. Hamdi, I. Sopyan, W.D. Teng, The influence of Ca/P ratio on the properties of HAp bioceramics, in International conference on smart materials and biotechnology in engineering. (2007)10.1117/12.779890 ↗
40. A. Samanta, S. Podder, C.K. Ghosh, M. Bhattacharya, J. Ghosh, A.K. Mallik, A. Dey, A.K. Mukhopadhyay, ROS mediated high anti-bacterial efficacy of strain tolerant layered phase pure nano-calcium hydroxide. J. Mech. Behav. Biomed. Mater. 72, 110–128 (2017)10.1016/j.jmbbm.2017.04.004 ↗
41. N. Abbasi, S. Hamlet, R.M. Love, N.-T. Nguyen, Porous scaffolds for bone regeneration. J. Sci.: Adv. Mater. Devices (2020). https://doi.org/10.1016/j.jsamd.2020.01.00710.1016/j.jsamd.2020.01.007 ↗
42. C.R.E. Bueno, D. Valentim, V.A.S. Marques, J.E. Gomes-Filho, L.T.A. Cintra, R.C. Jacinto, E. Dezan-Junior, Biocompatibility and biomineralization assessment of bioceramic-, epoxy-, and calcium hydroxide-based sealers. Braz. Oral Res. (2016). https://doi.org/10.1590/1807-3107BOR-2016.vol30.008110.1590/1807-3107BOR-2016.vol30.0081 ↗
43. A. Neumann, T. Reske, M. Held, K. Jahnke, C. Ragob, H.R. Maier, Comparative investigation of the biocompatibility of various silicon nitride ceramic qualities in vitro. J. Mater. Sci.—Mater. Med. 15(10), 1135–1140 (2004)10.1023/B:JMSM.0000046396.14073.92 ↗
44. X. Gai, C. Liu, G. Wang, Y. Qin, C. Fan, J. Liu, Y. Shi, A novel method for evaluating the dynamic biocompatibility of degradable biomaterials based on real-time cell analysis. Regener. Biomater. 7(3), 321–329 (2020)10.1093/rb/rbaa017 ↗
45. M.S. Kairon Mubina, S. Shailajha, R. Sankaranarayanan, M. Iyyadurai, Bone formation with high bacterial inhibition and low toxicity behavior by melding of Al2O3 on nanobioactive glass ceramics via sol-gel process. J. Sol-Gel Sci. Technol. (2022). https://doi.org/10.1007/s10971-022-05842-910.1007/s10971-022-05842-9 ↗
46. H. Sheng, N. Congqin, Z. Yue, C. Lei, L. Kaili, C. Jiang, Antibacterial activity of silicate bioceramics. J. Wuhan Univ. Technol.-Mater. Sci. Ed. 26(2), 226–230 (2011)10.1007/s11595-011-0202-8 ↗
47. J. Jeong, J.H. Kim, J.H. Shim, N.S. Hwang, C.Y. Heo, Bioactive calcium phosphate materials and applications in bone regeneration. Biomater. Res. (2019). https://doi.org/10.1186/s40824-018-0149-310.1186/s40824-018-0149-3 ↗
48. L. Fedunik-Hofman, A. De La Calle, S.W. Donne, Comparative kinetic analysis of CaCO3/CaO reaction system for energy storage and carbon capture. Appl. Sci. 9(21), 4601 (2019). https://doi.org/10.3390/app921460110.3390/app9214601 ↗
49. T. Kokubo, H. Takadama, How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 27(15), 2907–2915 (2006)10.1016/j.biomaterials.2006.01.017 ↗
50. D. Tadic, F. Peters, M. Epple, Continuous synthesis of amorphous carbonated apatites. Biomaterials 23(12), 2553–2559 (2002)10.1016/S0142-9612(01)00390-8 ↗
51. S. Palakurthy, P.A. Azeem, K. Venugopal Reddy, V. Penugurti, B. Manavathi, A Comparative study on in vitro behaviour of calcium silicate ceramics synthesized from bio-waste resources. J. Am. Ceram. Soc. (2019). https://doi.org/10.1111/jace.1674510.1111/jace.16745 ↗
52. N. Iwashita, X-ray powder diffraction, in Materials science and engineering of carbon. (Elsevier, Amsterdam, 2016), pp.7–25
53. W. Li, J. Zhou, Y.-Y. Xu, Study of the in vitro cytotoxicity testing of medical devices. Biomed. Rep. 3(5), 617–620 (2015). https://doi.org/10.3892/br.2015.48110.3892/br.2015.481 ↗