Bioactive behaviors of porous apatite- and wollastonite-containing glass-ceramic in two kinds of simulated body fluid

Simulated body fluid (SBF) has been widely used for assessment of bioactivities of different materials. Those kinds of conventional SBF (C-SBF) have a higher Cl⁻ concentration and a lower HCO₃⁻ concentration than those of human blood plasma. Therefore, a revised simulated body fluid (R-SBF), with ion concentrations including those of Cl⁻ and HCO₃⁻ exactly equal to those of human plasma, was recently developed. Porous glass-ceramic was used as the testing material to evaluate the two kinds of SBF. Results showed that C-SBF is considered more active than R-SBF because the porous glass-ceramic had a higher apatite formation rate on its surface,while R-SBF is considered to simulate the human body fluid more precisely than C-SBF.