journal article·2022-02-28

Polylactide microparticles stabilized by chitosan graft-copolymer as building blocks for scaffold fabrication via surface-selective laser sintering

T. S. Demina, T. N. Popyrina, E. D. Minaeva, A. A. Dulyasova, S. A. Minaeva, R. Tilkin, V. I. Yusupov, C. Grandfils, T. A. Akopova, N. V. Minaev, P. S. Timashev

Journal of Materials Research· Volume 37· Issue 4
Publisher page

Abstract

Surface-selective laser sintering (SSLS) is a specific version of selective laser sintering, which allows one to fabricate 3D structures with well-defined architectonic via selective melting of microparticle surface without alteration of their core. This mode of laser sintering requires a well-designed surface properties of the microparticles to adsorb laser irradiation. Water was chosen as safer sensitive absorber of laser radiation with a wavelength of 1.9 μm, i.e. one with low absorption coefficient by polymeric core. Biodegradable polylactide microparticles were fabricated via oil/water emulsion solvent evaporation technique using tailored-made chitosan-based macromolecules, which provided the effective interface stabilization during the microparticle fabrication and well balanced microparticle surface hydrophilicity to adsorb water. Especially build SSLS set-up was designed in order to monitor the effectiveness of the 3D scaffold fabrication from the obtained microparticles and to adapt the optimal laser radiation parameters with a wavelength of 1.9 μm (e.g. speed, line density, power).Graphical abstract
Source: expertdata · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Additive Manufacturing and 3D Printing Technologies · 3D Printing in Biomedical Research · Surface Modification and Superhydrophobicity

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (34)

Show source-provided references
1. T. Jiang, S.P. Nukavarapu, M. Deng, E. Jabbarzadeh, M.D. Kofron, S.B. Doty, W.I. Abdel-Fattah, C.T. Laurencin, Chitosan–poly(lactide-co-glycolide) microsphere-based scaffolds for bone tissue engineering: In vitro degradation and in vivo bone regeneration studies. Acta Biomater. 6, 3457–3470 (2010). https://doi.org/10.1016/j.actbio.2010.03.02310.1016/j.actbio.2010.03.023 ↗
2. L. Du, S. Yang, W. Li, H. Li, S. Feng, R. Zeng, B. Yu, L. Xiao, H.-Y. Nie, M. Tu, Scaffold composed of porous vancomycin-loaded poly(lactide-co-glycolide) microspheres: a controlled-release drug delivery system with shape-memory effect. Mater. Sci. Eng., C 78, 1172–1178 (2017). https://doi.org/10.1016/j.msec.2017.04.09910.1016/j.msec.2017.04.099 ↗
3. S. Yuan, F. Shen, C.K. Chua, K. Zhou, Polymeric composites for powder-based additive manufacturing: materials and applications. Prog. Polym. Sci. 91, 141–168 (2019). https://doi.org/10.1016/j.progpolymsci.2018.11.00110.1016/j.progpolymsci.2018.11.001 ↗
4. H. Lee, C.H.J. Lim, M.J. Low, N. Tham, V.M. Murukeshan, Y.J. Kim, Lasers in additive manufacturing: a review. Int. J. Precision Eng. Manuf. 4, 307–322 (2017). https://doi.org/10.1007/s40684-017-0037-710.1007/s40684-017-0037-7 ↗
5. E.N. Antonov, V.N. Bagratashvili, M.J. Whitaker, J.J.A.A. Barry, K.M. Shakesheff, A.N. Konovalov, V.K. Popov, S.M. Howdle, Three-dimensional bioactive and biodegradable scaffolds fabricated by surface-selective laser sintering. Adv. Mater. 17, 327–330 (2005). https://doi.org/10.1002/adma.20040083810.1002/adma.200400838 ↗
6. J.M. Kanczler, S.-H. Mirmalek-Sani, N.A. Hanley, A.L. Ivanov, J.J.A. Barry, C. Upton, K.M. Shakesheff, S.M. Howdle, E.N. Antonov, V.N. Bagratashvili, V.K. Popov, R.O.C. Oreffo, Biocompatibility and osteogenic potential of human fetal femur-derived cells on surface selective laser sintered scaffolds. Acta Biomater. 5, 2063–2071 (2009). https://doi.org/10.1016/j.actbio.2009.03.01010.1016/j.actbio.2009.03.010 ↗
7. K.F. Palmer, D. Williams, Optical properties of water in the near infrared. J Opt Soc Am 64, 1107–1110 (1974). https://doi.org/10.1364/JOSA.64.00110710.1364/JOSA.64.001107 ↗
8. E.N. Antonov, L.I. Krotova, N.V. Minaev, S.A. Minaeva, A.V. Mironov, V.K. Popov, V.N. Bagratashvili, Surface-selective laser sintering of thermolabile polymer particles using water as heating sensitizer. Quant. Electron. 45, 1023–1028 (2015). https://doi.org/10.1070/QE2015v045n11ABEH01581710.1070/QE2015v045n11ABEH015817 ↗
9. N.V. Minaev, T.S. Demina, S.A. Minaeva, A.A. Dulyasova, E.D. Minaeva, S.A. Gonchukov, T.A. Akopova, P.S. Timashev, The evolution of surface-selective laser sintering: modifying and forming 3D structures for tissue engineering. Bull. Russ. Acad. Sci. Phys. 84, 1315–1320 (2020). https://doi.org/10.3103/S106287382011019210.3103/S1062873820110192 ↗
10. E.A. Grebenik, V.D. Grinchenko, S.N. Churbanov, N.V. Minaev, B.S. Shavkuta, P.A. Melnikov, D.V. Butnaru, Y.A. Rochev, V.N. Bagratashvili, P.S. Timashev, Osteoinducing scaffolds with multi-layered biointerface. Biomed. Mater. 13, 054103 (2018). https://doi.org/10.1088/1748-605X/aac4cb10.1088/1748-605X/aac4cb ↗
11. A. Mazzoli, Selective laser sintering in biomedical engineering. Med. Biol. Eng. Compu. 51, 245–256 (2013). https://doi.org/10.1007/s11517-012-1001-x10.1007/s11517-012-1001-x ↗
12. H. Sawalha, K. Schroën, R. Boom, Biodegradable polymeric microcapsules: preparation and properties. Chem. Eng. J. 169, 1–10 (2011). https://doi.org/10.1016/j.cej.2011.02.07810.1016/j.cej.2011.02.078 ↗
13. E. Campos, J. Branquinho, A.S. Carreira, A. Carvalho, P. Coimbra, P. Ferreira, M.H. Gil, Designing polymeric microparticles for biomedical and industrial applications. Eur. Polymer J. 49, 2005–2021 (2013). https://doi.org/10.1016/j.eurpolymj.2013.04.03310.1016/j.eurpolymj.2013.04.033 ↗
14. Y. Hong, C. Gao, Y. Xie, Y. Gong, J. Shen, Collagen-coated polylactide microspheres as chondrocyte microcarriers. Biomaterials 26, 6305–6313 (2005). https://doi.org/10.1016/j.biomaterials.2005.03.03810.1016/j.biomaterials.2005.03.038 ↗
15. L. Yang, J. Zhang, J. He, J. Zhang, Z. Gan, Fabrication, hydrolysis and cell cultivation of microspheres from cellulose-graft-poly(l-lactide) copolymers. RSC Adv. 6, 17617–17623 (2016). https://doi.org/10.1039/c5ra25993b10.1039/c5ra25993b ↗
16. T.S. Demina, T.A. Akopova, L.V. Vladimirov, A.N. Zelenetskii, E.A. Markvicheva, C. Grandfils, Polylactide-based microspheres prepared using solid-state copolymerized chitosan and d,l-lactide. Mater. Sci. Eng. C 59, 333–338 (2016). https://doi.org/10.1016/j.msec.2015.09.09410.1016/j.msec.2015.09.094 ↗
17. T.S. Demina, M.G. Drozdova, C. Sevrin, P. Compère, T.A. Akopova, E. Markvicheva, C. Grandfils, Biodegradable cell microcarriers based on chitosan/polyester graft-copolymers. Molecules 25, 1949 (2020). https://doi.org/10.3390/molecules2508194910.3390/molecules25081949 ↗
18. E. Bouyer, G. Mekhloufi, V. Rosilio, J.-L. Grossiord, F. Agnely, Proteins, polysaccharides, and their complexes used as stabilizers for emulsions: alternatives to synthetic surfactants in the pharmaceutical field? Int. J. Pharm. 436, 359–378 (2012). https://doi.org/10.1016/j.ijpharm.2012.06.05210.1016/j.ijpharm.2012.06.052 ↗
19. V. Calabrese, J.C. Courtenay, K.J. Edler, J.L. Scott, Pickering emulsions stabilized by naturally derived or biodegradable particles. Curr. Opin. Green Sustain. Chem. 12, 83–90 (2018). https://doi.org/10.1016/j.cogsc.2018.07.00210.1016/j.cogsc.2018.07.002 ↗
20. T.S. Demina, L.A. Kilyashova, T.N. Popyrina, E.A. Svidchenko, S. Bhuniya, T.A. Akopova, C. Grandfils, Polysaccharides as stabilizers for polymeric microcarriers fabrication. Polymers 13, 3045 (2021). https://doi.org/10.3390/polym1318304510.3390/polym13183045 ↗
21. M.S. Rodriguez, L.A. Albertengo, E. Agullo, Emulsification capacity of chitosan. Carbohyd. Polym. 48, 271–276 (2002). https://doi.org/10.1016/S0144-8617(01)00258-210.1016/S0144-8617(01)00258-2 ↗
22. R. Cheung, T. Ng, J. Wong, W. Chan, Chitosan: an update on potential biomedical and pharmaceutical applications. Mar. Drugs 13, 5156–5186 (2015). https://doi.org/10.3390/md1308515610.3390/md13085156 ↗
23. A. Anitha, S. Sowmya, P.T.T.S.S. Kumar, S. Deepthi, K.P.P. Chennazhi, H. Ehrlich, M. Tsurkan, R. Jayakumar, Chitin and chitosan in selected biomedical applications. Prog. Polym. Sci. 39, 1644–1667 (2014). https://doi.org/10.1016/j.progpolymsci.2014.02.00810.1016/j.progpolymsci.2014.02.008 ↗
24. S.K. Sahoo, J. Panyam, S. Prabha, V. Labhasetwar, Residual polyvinyl alcohol associated with poly (d,l-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake. J. Control. Release 82, 105–114 (2002). https://doi.org/10.1016/S0168-3659(02)00127-X10.1016/S0168-3659(02)00127-X ↗
25. T.S. Demina, C. Grandfils, Solid-state modified polylactides for processing of 3D materials with enhanced biocompatibility. Mater. Today 12, 93–96 (2019). https://doi.org/10.1016/j.matpr.2019.03.07210.1016/j.matpr.2019.03.072 ↗
26. S.M. Ahsan, M. Thomas, K.K. Reddy, S.G. Sooraparaju, A. Asthana, I. Bhatnagar, Chitosan as biomaterial in drug delivery and tissue engineering. Int. J. Biol. Macromol. 110, 97–109 (2018). https://doi.org/10.1016/j.ijbiomac.2017.08.14010.1016/j.ijbiomac.2017.08.140 ↗
27. A. Privalova, E. Markvicheva, C. Sevrin, M. Drozdova, C. Kottgen, B. Gilbert, M. Ortiz, C. Grandfils, Biodegradable polyester-based microcarriers with modified surface tailored for tissue engineering. J. Biomed. Mater. Res. A 103, 939–948 (2015). https://doi.org/10.1002/jbm.a.3523110.1002/jbm.a.35231 ↗
28. H.-T. Liao, M.-Y. Lee, W.-W. Tsai, H.-C. Wang, W.-C. Lu, Osteogenesis of adipose-derived stem cells on polycaprolactone-β-tricalcium phosphate scaffold fabricated via selective laser sintering and surface coating with collagen type I. J. Tissue Eng. Regen. Med. 10, E337–E353 (2016). https://doi.org/10.1002/term.181110.1002/term.1811 ↗
29. C.H. Chen, M.Y. Lee, V.B.H. Shyu, Y.C. Chen, C.T. Chen, J.P. Chen, Surface modification of polycaprolactone scaffolds fabricated via selective laser sintering for cartilage tissue engineering. Mater. Sci. Eng., C 40, 389–397 (2014). https://doi.org/10.1016/j.msec.2014.04.02910.1016/j.msec.2014.04.029 ↗
30. K.N. Bardakova, E.A. Grebenik, E.V. Istranova, L.P. Istranov, Y.V. Gerasimov, A.G. Grosheva, T.M. Zharikova, N.V. Minaev, B.S. Shavkuta, D.S. Dudova, S.V. Kostyuk, N.N. Vorobeva, V.N. Bagratashvili, P.S. Timashev, R.K. Chailakhyan, Reinforced hybrid collagen sponges for tissue engineering. Bull. Exp. Biol. Med. 165, 142–147 (2018). https://doi.org/10.1007/s10517-018-4116-810.1007/s10517-018-4116-8 ↗
31. K.N. Bardakova, E.A. Grebenik, N.V. Minaev, S.N. Churbanov, Z. Moldagazyeva, G.E. Krupinov, S.V. Kostjuk, P.S. Timashev, Tailoring the collagen film structural properties via direct laser crosslinking of star-shaped polylactide for robust scaffold formation. Mater. Sci. Eng. C 107, 110300 (2020). https://doi.org/10.1016/j.msec.2019.11030010.1016/j.msec.2019.110300 ↗
32. T.S. Demina, A.S. Kuryanova, N.A. Aksenova, A.G. Shubnyy, T.N. Popyrina, Y.V. Sokovikov, E.V. Istranova, P.L. Ivanov, P.S. Timashev, T.A. Akopova, Chitosan-g-oligo/polylactide copolymer non-woven fibrous mats containing protein: from solid-state synthesis to electrospinning. RSC Adv. 9, 37652–37659 (2019). https://doi.org/10.1039/C9RA07667K10.1039/C9RA07667K ↗
33. T.N. Popyrina, E.A. Svidchenko, T.S. Demina, T.A. Akopova, A.N. Zelenetsky, Effect of the chemical structure of chitosan copolymers with oligolactides on the morphology and properties of macroporous hydrogels based on them. Polym. Sci. Ser. B 63, 536–543 (2021). https://doi.org/10.1134/S156009042105010910.1134/S1560090421050109 ↗
34. T.S. Demina, C. Sevrin, C. Kapchiekue, T.A. Akopova, C. Grandfils, Chitosan-g-polyester microspheres: effect of length and composition of grafted chains. Macromol. Mater. Eng. 304, 1900203 (2019). https://doi.org/10.1002/mame.20190020310.1002/mame.201900203 ↗