journal article·2023-01-14Open access

Facet of 4D printing in biomedicine

Vidhi Mathur, Prachi Agarwal, Varadharajan Srinivasan, Amit Panwar, Kirthanashri S. Vasanthan

Journal of Materials Research· Volume 38· Issue 1

Abstract

Abstract Owing to the success of three-dimensional (3D) printing in biomedical applications, the latest addition to the technology is four-dimensional (4D) printing, which has gained tremendous interest since 2012. 4D printing is being considered as an upgradation and extension of 3D that includes time as a fourth dimension with the utilization of smart biomaterials, and upon the application of any external stimulus, the shape and size of the printed structure change with time. In this review, we highlight the basic techniques involved in 4D printing, the shape memory effect, and various stimuli like light, temperature, pH, etc., that cause the shape change, leading to the transformation of the structures fabricated. 4D printing using smart materials demonstrates shape memory property and their possible applications in the field of biomedicine and regenerative medicine are discussed in detail. The authors have focused on 4D printing of various tissues, with a special highlight on bone and dental tissue. Graphical abstract
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Research context

OpenAlex topics: Advanced Materials and Mechanics · Polymer composites and self-healing · 3D Printing in Biomedical Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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