Microstructure, Corrosion, Dielectric, Thrombogenicity, Wettability and Mechanical Investigation of PMMA/HAp Pellet and PMMA/HAp Coating on Al2O3: A Comparative Study
Source abstract
Abstract
Despite of possessing very high biocompatibility and osteointegrating properties, HAp exhibits poor mechanical strength and cannot be used in high load-bearing areas. To improve the drawbacks of HAp, it can be either doped with polymeric material or can be coated on some substrate having high mechanical strength. Polymeric substances are known for their mechanical strength and non-toxicity. Addition of polymers in the HAp matrix enhances the properties of HAp. Poly methyl methacrylate (PMMA) is used as bone cement and possesses excellent antimicrobial properties. It is doped inside the HAp matrix to modify some of the drawbacks of HAp, such as brittleness, degeneration, the growth and spread of microbes and bacteria over time. α-Al2O3 was chosen because of its chemical inertness, high mechanical strength, resistant to corrosion, wear and tear. The present study focuses on the comparison of doping of PMMA in HAp and PMMA-doped HAp coating on α-Al2O3, which is being studied first time. The changes in the phase, surface morphology, corrosion resistance, optical contact angle and mechanical behaviour of both the coated and doped samples were studied. The hardness of the coated samples and the doped samples was found to be higher than the pure HAp samples. The dielectric properties of both the samples were studied, and it was observed that initially at lower frequency, the impedance of doped samples was lower in comparison to coated samples. Coated samples showed higher contact angle in comparison to doped samples. Clotting behaviour was studied using whole blood clotting method.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Orthopaedic implants and arthroplasty · Polymer Nanocomposite Synthesis and Irradiation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (38)
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