Mechanical Properties, Biodegradation, and Biocompatibility of Porous Mg Alloy Scaffolds for Load Bearing Bone Applications
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OpenAlex topics: Magnesium Alloys: Properties and Applications · Bone Tissue Engineering Materials · Orthopaedic implants and arthroplasty
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References (68)
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1. Q. Xie, A. Ma, J. Jiang, H. Liu, Z. Cheng and Y. Gu, Tailoring the corrosion behavior and mechanism of AZ31 magnesium alloys by different Ca contents for marine application, Corros. Sci., 2021, 192, p 109842.10.1016/j.corsci.2021.109842 ↗
2. P.P. Wu, F.J. Xu, K.K. Deng, F.Y. Han, Z.Z. Zhang and R. Gao, Effect of extrusion on corrosion properties of Mg–2Ca–xAl (x = 0, 2, 3, 5) alloys, Corros. Sci., 2017, 127, p 280–290.10.1016/j.corsci.2017.08.014 ↗
3. B. Homayun and A. Afshar, Microstructure, mechanical properties, corrosion behavior and cytotoxicity of Mg–Zn–Al–Ca alloys as biodegradable materials, J. Alloy. Compd., 2014, 607, p 1.10.1016/j.jallcom.2014.04.059 ↗
4. E. Mostaed, M. Sikora-Jasinska, L. Wang, A. Mostaed, I.M. Reaney and J.W. Drelich, Tailoring the mechanical and degradation performance of Mg–2.0Zn–0.5Ca–0.4Mn alloy through microstructure design, JOM, 2020, 72(5), p 1880–1891. https://doi.org/10.1007/s11837-020-04085-910.1007/s11837-020-04085-9 ↗
5. S.S. Prasad, S.B. Prasad, K. Verma, R.K. Mishra, V. Kumar and S. Singh, The role and significance of magnesium in modern day research—a review, J. Magnes. Alloy., 2022, 10(1), p 1–61.10.1016/j.jma.2021.05.012 ↗
6. J. Asadi, B. Korojy, S.A. Hosseini and M. Alishahi, Effect of cell structure on mechanical and bio-corrosion behavior of biodegradable Mg–Zn–Ca foam, Mater. Today Commun., 2021, 28, p 102715.10.1016/j.mtcomm.2021.102715 ↗
7. M.H. Kang, T.S. Jang, S.W. Kim, H.S. Park, J. Song, H.E. Kim, K.H. Jung and H.D. Jung, MgF2-coated porous magnesium/alumina scaffolds with improved strength, corrosion resistance, and biological performance for biomedical applications, Mater. Sci. Eng. C, 2016, 62, p 634–642.10.1016/j.msec.2016.01.085 ↗
8. K.H. Cheon, C. Gao, M.H. Kang, H.D. Jung, T.S. Jang, H.E. Kim, Y. Li and J. Song, A crack-free anti-corrosive coating strategy for magnesium implants under deformation, Corros. Sci., 2018, 132, p 116–124.10.1016/j.corsci.2017.12.030 ↗
9. H. Kapłon, C. Blawert, J. Chęcmanowski and K. Naplocha, Development of open-porosity magnesium foam produced by investment casting, J. Magnes. Alloy., 2022, 10(7), p 1941–1956.10.1016/j.jma.2022.01.003 ↗
10. N. Aslan, B. Aksakal and F. Findik, Fabrication of porous-Ti6Al4V alloy by using hot pressing technique and Mg space holder for hard-tissue biomedical applications, J. Mater. Sci. Mater. Med., 2021, 32(7), p 80.10.1007/s10856-021-06546-2 ↗
11. N. Singh, U. Batra, K. Kumar, N. Ahuja and A. Mahapatro, Progress in bioactive surface coatings on biodegradable Mg alloys: a critical review towards clinical translation, Bioact. Mater., 2023, 19, p 717–757.
12. E. Yılmaz, A. Gökçe, F. Findik, H.O. Gulsoy and O. İyibilgin, Mechanical properties and electrochemical behavior of porous Ti–Nb biomaterials, J. Mech. Behav. Biomed. Mater., 2018, 87, p 59–67.10.1016/j.jmbbm.2018.07.018 ↗
13. Y. Li, J. Zhou, P. Pavanram, M.A. Leeflang, L.I. Fockaert, B. Pouran, N. Tümer, K.U. Schröder, J.M. Mol, H. Weinans and H. Jahr, Additively manufactured biodegradable porous magnesium, Acta Biomater., 2018, 67, p 378–392.10.1016/j.actbio.2017.12.008 ↗
14. M.H. Kang, H. Lee, T.S. Jang, Y.J. Seong, H.E. Kim, Y.H. Koh, J. Song and H.D. Jung, Biomimetic porous Mg with tunable mechanical properties and biodegradation rates for bone regeneration, Acta Biomater., 2019, 84, p 453–467.10.1016/j.actbio.2018.11.045 ↗
15. P. Jenei, H. Choi, A. Tóth, H. Choe and J. Gubicza, Mechanical behavior and microstructure of compressed Ti foams synthesized via freeze casting, J. Mech. Behav. Biomed. Mater., 2016, 63, p 407–416. https://doi.org/10.1016/j.jmbbm.2016.07.01210.1016/j.jmbbm.2016.07.012 ↗
16. J.W. Drelich and J. Goldman, Bioresorbable vascular metallic scaffolds: current status and research trends, Curr. Opin. Biomed. Eng., 2022, 24, p 100411.10.1016/j.cobme.2022.100411 ↗
17. L. Yuan, S. Ding and C. Wen, Additive manufacturing technology for porous metal implant applications and triple minimal surface structures: a review, Bioact. Mater., 2019, 4, p 56–70.
18. T. Kokubo, H. Takadama, How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 2006, 27, p 2907–2915.10.1016/j.biomaterials.2006.01.017 ↗
19. A.P. Saad, R.A. Rahim, M.N. Harun, H. Basri, J. Abdullah, M.R. Kadir and A. Syahrom, The influence of flow rates on the dynamic degradation behaviour of porous magnesium under a simulated environment of human cancellous bone, Mater. Des., 2017, 122, p 268–279.10.1016/j.matdes.2017.03.029 ↗
20. Q. Dong, Y. Li, H. Jiang, X. Zhou, H. Liu, M. Lu et al., 3D-cubic interconnected porous Mg-based scaffolds for bone repair, J. Magnes. Alloy., 2021, 9(4), p 1329–1338.10.1016/j.jma.2020.05.022 ↗
21. S. Singh and N. Bhatnagar, A novel approach to fabricate 3D open cellular structure of Mg10Zn alloy with controlled morphology, Mater. Lett., 2018, 212, p 62–64.10.1016/j.matlet.2017.10.071 ↗
22. G. Jia, Y. Hou, C. Chen, J. Niu, H. Zhang, H. Huang et al., Precise fabrication of open porous Mg scaffolds using NaCl templates: relationship between space holder particles, pore characteristics and mechanical behavior, Mater. Des., 2018, 140, p 106–113.10.1016/j.matdes.2017.11.064 ↗
23. S. Singh, P. Vashisth, A. Shrivastav and N. Bhatnagar, Synthesis and characterization of a novel open cellular Mg-based scaffold for tissue engineering application, J. Mech. Behav. Biomed. Mater., 2019, 94, p 54–62.10.1016/j.jmbbm.2019.02.010 ↗
24. C.L. Wu, W.J. Xie and H.C. Man, Laser additive manufacturing of biodegradable Mg-based alloys for biomedical applications: a review, J. Magnes. Alloy., 2022, 10(4), p 915–937.10.1016/j.jma.2021.12.014 ↗
25. J. Dong, P. Lin, N.E. Putra, N. Tümer, M.A. Leeflang, Z. Huan et al., Extrusion-based additive manufacturing of Mg–Zn/bioceramic composite scaffolds, Acta Biomater., 2022, 151, p 628–646.10.1016/j.actbio.2022.08.002 ↗
26. H. Kabir, K. Munir, C. Wen and Y. Li, Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: biomechanical and biocorrosion perspectives, Bioact. Mater., 2021, 6(3), p 836–879.
27. O.R. Bagshaw, F. Moradi, C.S. Moffatt, H.A. Hettwer, P. Liang, J. Goldman, J.W. Drelich and J.A. Stuart, Bioabsorbable metal zinc differentially affects mitochondria in vascular endothelial and smooth muscle cells, Biomater. Biosyst., 2021, 4, p 100027.
28. P.K. Bowen, J. Drelich and J. Goldman, Zinc exhibits ideal physiological corrosion behavior for bioabsorbable stents, Adv. Mater., 2013, 25(18), p 2577–2582.10.1002/adma.201300226 ↗
29. D. Rahmatabadi, M. Pahlavani, A. Bayati, R. Hashemi and J.M. Marzbanrad, Evaluation of fracture toughness and rupture energy absorption capacity of as-rolled LZ71 and LZ91 Mg alloy sheet, Mater. Res. Express, 2018, 6(3), p 036517.10.1088/2053-1591/aaf54f ↗
30. K. Xie, N. Wang, Y. Guo, S. Zhao, J. Tan, L. Wang et al., Additively manufactured biodegradable porous magnesium implants for elimination of implant-related infections: an in vitro and in vivo study, Bioact. Mater., 2022, 8, p 140–152.
31. J.O. Osorio-Hernández, M.A. Suarez, R. Goodall, G.A. Lara-Rodriguez, I. Alfonso and I.A. Figueroa, Manufacturing of open-cell Mg foams by replication process and mechanical properties, Mater. Des., 2014, 64, p 136–141.10.1016/j.matdes.2014.07.015 ↗
32. E. Willbold, X. Gu, D. Albert, K. Kalla, K. Bobe, M. Brauneis et al., Effect of the addition of low rare earth elements (lanthanum, neodymium, cerium) on the biodegradation and biocompatibility of magnesium, Acta Biomater., 2015, 11, p 554–562.10.1016/j.actbio.2014.09.041 ↗
33. M. Li, F. Benn, T. Derra, N. Kröger, M. Zinser, R. Smeets et al., Microstructure, mechanical properties, corrosion resistance and cytocompatibility of WE43 Mg alloy scaffolds fabricated by laser powder bed fusion for biomedical applications, Mater. Sci. Eng. C, 2021, 119, p 111623.10.1016/j.msec.2020.111623 ↗
34. X. Wei, W. Zhou, Z. Tang, H. Wu, Y. Liu, H. Dong et al., Magnesium surface-activated 3D printed porous PEEK scaffolds for in vivo osseointegration by promoting angiogenesis and osteogenesis, Bioact. Mater., 2023, 20, p 16–28.
35. A.P. Md Saad and A. Syahrom, Study of dynamic degradation behaviour of porous magnesium under physiological environment of human cancellous bone, Corros. Sci., 2018, 131, p 45–56.10.1016/j.corsci.2017.10.026 ↗
36. D. Rahmatabadi, R. Hashemi, M. Tayyebi and A. Bayati, Investigation of mechanical properties, formability, and anisotropy of dual phase Mg–7Li–1Zn, Mater. Res. Express, 2019, 6(9), p 096543.10.1088/2053-1591/ab2de6 ↗
37. N.H. Mostafa, Z.N. Ismarrubie, S.M. Sapuan and M.T. Sultan, Effect of equi-biaxially fabric prestressing on the tensile performance of woven E-glass/polyester reinforced composites, J. Reinf. Plast. Compos., 2016, 35(14), p 1093–1103.10.1177/0731684416638553 ↗
38. M. Mariam, M. Afendi, M.A. Majid, M.J. Ridzuan, A.I. Azmi and M.T. Sultan, Influence of hydrothermal ageing on the mechanical properties of an adhesively bonded joint with different adherends, Compos. B Eng., 2019, 15(165), p 572–585.10.1016/j.compositesb.2019.02.032 ↗
39. L. Zhao, Z. Zhang, Y. Song, S. Liu, Y. Qi, X. Wang et al., Mechanical properties and in vitro biodegradation of newly developed porous Zn scaffolds for biomedical applications, Mater. Des., 2016, 108, p 136–144.10.1016/j.matdes.2016.06.080 ↗
40. Mq. Cheng, T. Wahafu, G.-f Jiang, W. Liu, Y.-q Qiao, X.-c Peng, T. Cheng, X.-l Zhang, G. He and X.-y Liu, A novel open-porous magnesium scaffold with controllable microstructures and properties for bone regeneration, Sci. Rep., 2016, 6(1), p 24134. https://doi.org/10.1038/srep2413410.1038/srep24134 ↗
41. R. Yao, S. Han, Y. Sun, Y. Zhao, R. Shan, L. Liu et al., Fabrication and characterization of biodegradable Zn scaffold by vacuum heating-press sintering for bone repair, Biomater. Adv., 2022, 138, p 212968.10.1016/j.bioadv.2022.212968 ↗
42. B. Yin, J. Liu, B. Peng, M. Zhou, B. Liu, X. Ma et al., Influence of layer thickness on formation quality, microstructure, mechanical properties, and corrosion resistance of WE43 magnesium alloy fabricated by laser powder bed fusion. J. Magnes. Alloy., 2022.
43. J. Čapek and D. Vojtěch, Properties of porous magnesium prepared by powder metallurgy, Mater. Sci. Eng. C, 2013, 33(1), p 564–569.10.1016/j.msec.2012.10.002 ↗
44. Y. Hou, G. Jia, R. Yue, C. Chen, J. Pei, H. Zhang et al., Synthesis of biodegradable Zn-based scaffolds using NaCl templates: relationship between porosity, compressive properties and degradation behavior, Mater Charact, 2018, 137, p 162–169.10.1016/j.matchar.2018.01.033 ↗
45. D. Zhao, C. Han, Y. Li, J. Li, K. Zhou, Q. Wei et al., Improvement on mechanical properties and corrosion resistance of titanium-tantalum alloys in-situ fabricated via selective laser melting, J. Alloy. Compd., 2019, 804, p 288–298.10.1016/j.jallcom.2019.06.307 ↗
46. G. Jia, C. Chen, J. Zhang, Y. Wang, R. Yue, J.C. Bérengère, L. Feyerabend, R. Willumeit-Roemer, H. Zhang, M. Xiong, H. Huang, G. Yuan and F. Feyerabend, In vitro degradation behavior of Mg scaffolds with three-dimensional interconnected porous structures for bone tissue engineering, Corros. Sci., 2018, 144, p 301–312. https://doi.org/10.1016/j.corsci.2018.09.00110.1016/j.corsci.2018.09.001 ↗
47. H.R. Bakhsheshi-Rad, E. Hamzah, S. Farahany and M.P. Staiger, The mechanical properties and corrosion behavior of quaternary Mg–6Zn–0.8Mn–xCa alloys, J. Mater. Eng. Perform., 2015, 24(2), p 598–608. https://doi.org/10.1007/s11665-014-1271-610.1007/s11665-014-1271-6 ↗
48. H. Zhuang, Y. Han and A. Feng, Preparation, mechanical properties and in vitro biodegradation of porous magnesium scaffolds, Mater. Sci. Eng. C, 2008, 28(8), p 1462–1466.10.1016/j.msec.2008.04.001 ↗
49. H.R. Bakhsheshi-Rad, E. Hamzah, M.P. Staiger, G.J. Dias, Z. Hadisi, M. Saheban et al., Drug release, cytocompatibility, bioactivity, and antibacterial activity of doxycycline loaded Mg–Ca–TiO2 composite scaffold, Mater. Des., 2018, 139, p 212–221.10.1016/j.matdes.2017.10.072 ↗
50. E. Dayaghi, H.R. Bakhsheshi-Rad, E. Hamzah, A. Akhavan-Farid, A.F. Ismail, M. Aziz et al., Magnesium–zinc scaffold loaded with tetracycline for tissue engineering application: in vitro cell biology and antibacterial activity assessment, Mater. Sci. Eng. C, 2019, 102, p 53–65.10.1016/j.msec.2019.04.010 ↗
51. R. Bonithon, A.P. Kao, M.P. Fernández, J.N. Dunlop, G.W. Blunn, F. Witte et al., Multi-scale mechanical and morphological characterisation of sintered porous magnesium-based scaffolds for bone regeneration in critical-sized defects, Acta Biomater., 2021, 127, p 338–352.10.1016/j.actbio.2021.03.068 ↗
52. Y. Chen, J.E. Frith, A. Dehghan-Manshadi, H. Attar, D. Kent, N.D.M. Soro et al., Mechanical properties and biocompatibility of porous titanium scaffolds for bone tissue engineering, J. Mech. Behav. Biomed. Mater., 2017, 75, p 169–174.10.1016/j.jmbbm.2017.07.015 ↗
53. M.S. Ardakani, E. Mostaed, M. Sikora-Jasinska, S.L. Kampe and J.W. Drelich, The effects of alloying with Cu and Mn and thermal treatments on the mechanical instability of Zn–0.05Mg alloy, Mater. Sci. Eng. A, 2020, 770, p 138529. https://doi.org/10.1016/j.msea.2019.13852910.1016/j.msea.2019.138529 ↗
54. L.G. Katarivas, A. Leon, A. Kafri, Y. Ventura, J.W. Drelich, J. Goldman et al., Evaluation of biodegradable Zn–1%Mg and Zn–1%Mg–05%Ca alloys for biomedical applications, J. Mater. Sci. Mater. Med., 2017, 28(11), p 174.10.1007/s10856-017-5973-9 ↗
55. H.R. Bakhsheshi-Rad, E. Dayaghi, A.F. Ismail, A.Z. Madzlan, A. Akhavan-Farid and C.H. Xiongbiao, Synthesis and in-vitro characterization of biodegradable porous magnesium-based scaffolds containing silver for bone tissue engineering, Trans. Nonferr. Metals Soc. Ch., 2019, 29(5), p 984–996.10.1016/S1003-6326(19)65007-7 ↗
56. S. Abazari, A. Shamsipur, H.R. Bakhsheshi-Rad, J.W. Drelich, J. Goldman, S. Sharif et al., Magnesium-based nanocomposites: a review from mechanical, creep and fatigue properties, J. Magnes. Alloy., 2023, 11(8), p 2655–2687.10.1016/j.jma.2023.08.005 ↗
57. S.D. Fernández-Silva, M. García-Morales, C. Ruffel and M.A. Delgado, Influence of the nanoclay concentration and oil viscosity on the rheological and tribological properties of nanoclay-based ecolubricants, Lubricants, 2021, 9(1), p 8.10.3390/lubricants9010008 ↗
58. J. Venezuela and M.S. Dargusch, The influence of alloying and fabrication techniques on the mechanical properties, biodegradability and biocompatibility of zinc: a comprehensive review, Acta Biomater., 2019, 87, p 1–40.10.1016/j.actbio.2019.01.035 ↗
59. N. Yang, J. Venezuela, S. Almathami and M. Dargusch, Zinc-nutrient element based alloys for absorbable wound closure devices fabrication: current status, challenges, and future prospects, Biomaterials, 2022, 280, p 121301.10.1016/j.biomaterials.2021.121301 ↗
60. M. Daroonparvar, H.R. Bakhsheshi-Rad, A. Saberi, M. Razzaghi, A.K. Kasar, S. Ramakrishna et al., Surface modification of magnesium alloys using thermal and solid-state cold spray processes: challenges and latest progresses, J. Magnes. Alloy., 2022, 10(8), p 2025–2061.10.1016/j.jma.2022.07.012 ↗
61. H.R. Bakhsheshi-Rad, M. Daroonparvar, M.A.M. Yajid, P. Kumar, M. Razzaghi, A.F. Ismail, S. Sharif and F. Berto, Characterization and corrosion behavior evaluation of nanostructured TiO2 and Al2O3–13 wt.%TiO2 coatings on aluminum alloy prepared via high-velocity oxy-fuel spray, J. Mater. Eng. Perform., 2021, 30(2), p 1356–1370. https://doi.org/10.1007/s11665-020-05333-410.1007/s11665-020-05333-4 ↗
62. M.C.A. Isaza, D.B. Zuluaga, J.S. Rudas, D.H.A. Estupiñán, R.J.M. Herrera and J.M. Meza, Mechanical and corrosion behavior of plasma electrolytic oxidation coatings on AZ31B Mg alloy reinforced with multiwalled carbon nanotubes, J. Mater. Eng. Perform., 2020, 29, p 1135–1145.10.1007/s11665-020-04633-z ↗
63. H.R. Bakhsheshi-Rad, E. Hamzah, H.Y. Tok, M. Kasiri-Asgarani, S. Jabbarzare and M. Medraj, Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg–Ca–Zn and Mg–Ca–Zn–Bi alloys, J. Mater. Eng. Perform., 2017, 26, p 653–666.10.1007/s11665-016-2499-0 ↗
64. G.V. Jagadeesh and S.S. Gangi, Tribological performance evaluation of ball burnished magnesium alloy for bioresorbable implant applications, J. Mater. Eng. Perform., 2022, 31(2), p 1170–1186.10.1007/s11665-021-06228-8 ↗
65. A. Ercetin, Application of the hot press method to produce new Mg alloys: characterization, mechanical properties, and effect of Al addition, J. Mater. Eng. Perform., 2021, 30(6), p 4254–4262.10.1007/s11665-021-05814-0 ↗
66. T.O. Olugbade, B.O. Omiyale and O.T. Ojo, Corrosion, corrosion fatigue, and protection of magnesium alloys: mechanisms, measurements, and mitigation, J. Mater. Eng. Perform., 2022, 1, p 1–21.
67. M. Sozańska and A. Mościcki, Investigation of the susceptibility of the WE54 magnesium-based alloy to stress corrosion cracking, J. Mater. Eng. Perform., 2020, 29(2), p 949–963.10.1007/s11665-019-04550-w ↗
68. M. Razzaghi, M. Kasiri-Asgarani, H.R. Bakhsheshi-Rad and H. Ghayour, In vitro degradation, antibacterial activity and cytotoxicity of Mg–3Zn–xAg nanocomposites synthesized by mechanical alloying for implant applications, J. Mater. Eng. Perform., 2019, 28(3), p 1441–1455.10.1007/s11665-019-03923-5 ↗