journal article·2014-03

PEGylated WS2 Nanosheets as a Multifunctional Theranostic Agent for in vivo Dual‐Modal CT/Photoacoustic Imaging Guided Photothermal Therapy

Liang Cheng, Jingjing Liu, Xing Gu, Hua Gong, Xiaoze Shi, Teng Liu, Chao Wang, Xiaoyong Wang, Gang Liu, Huaiyong Xing, Wenbo Bu, Baoquan Sun, Zhuang Liu

Advanced Materials· Volume 26· Issue 12
Publisher page

Abstract

A new generation of photothermal theranostic agents is developed based on PEGylated WS2 nanosheets. Bimodal in vivo CT/photoacoustic imaging reveals strong tumor contrast after either intratumoral or intravenous injection of WS2 -PEG. In vivo photothermal treatment is then conducted in a mouse tumor model, achieving excellent therapeutic efficacy with complete ablation of tumors. This work promises further exploration of transition-metal dichalcogenides for biomedical applications, such as cancer imaging and therapy.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Extracellular vesicles in disease · Photoacoustic and Ultrasonic Imaging

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute of Functional Nano & Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou, Nano Science and Technology Soochow University Suzhou Jiangsu 215123 China

Center for Molecular Imaging and Translational Medicine School of Public Health, Xiamen University Xiamen 361005 China

State Key Laboratory of High performance Ceramics and Superfine Microstructures Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 China

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