Porphyrin-functionalized mesoporous organosilica nanoparticles for two-photon imaging of cancer cells and drug delivery

Chiara Mauriello-Jimenez; Jonas Croissant; Marie Maynadier; Xavier Cattoën; Michel Wong Chi Man; Julien Vergnaud; Vincent Chaleix; Vincent Sol; Marcel Garcia; Magali Gary-Bobo; Laurence Raehm; Jean-Olivier Durand

doi:10.1039/c5tb00315f

journal article·2015Open access

Porphyrin-functionalized mesoporous organosilica nanoparticles for two-photon imaging of cancer cells and drug delivery

Chiara Mauriello-Jimenez, Jonas Croissant, Marie Maynadier, Xavier Cattoën, Michel Wong Chi Man, Julien Vergnaud, Vincent Chaleix, Vincent Sol, Marcel Garcia, Magali Gary-Bobo, Laurence Raehm, Jean-Olivier Durand

Journal of Materials Chemistry B· Volume 3· Issue 18

Publisher page Open full text

Source abstract

Abstract

The synthesis of a zinc porphyrin derivative possessing eight triethoxysilyl groups was performed through a CuAAC-click reaction. This porphyrin was covalently entrapped in ethenylene-bridged mesoporous organosilica nanoparticles which efficiently allowed performing doxorubicin delivery and two-photon imaging of breast cancer cells.

Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗

Research context

Nanomaterials

OpenAlex topics: Porphyrin and Phthalocyanine Chemistry · Photodynamic Therapy Research Studies · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institut Charles Gerhardt Montpellier

UMR-5253 CNRS-UM2-ENSCM-UM1cc 1701

F-34095 Montpellier cedex 05

France

Institut des Biomolécules Max Mousseron UMR 5247 CNRS; UM 1; UM 2 - Faculté de Pharmacie

34093 Montpellier Cedex 05

NanoMedSyn

Faculté de Pharmacie

Institut Néel

CNRS and Université Grenoble-Alpes

38042 Grenoble

Laboratoire de Chimie des Substances Naturelles

EA 1069

Université de Limoges

Faculté des Sciences et Techniques

87060 Limoges cedex

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