A core–shell metal–organic-framework (MOF)-based smart nanocomposite for efficient NIR/H 2 O 2 -responsive photodynamic therapy against hypoxic tumor cells
Source abstract
Abstract
Core-shell MOF-based smart nanocomposite UCNPs/MB@ZIF-8@catalase (UCNPs = upconversion nanoparticles; MB = methylene blue; ZIF = zeolitic imidazolate framework) has been constructed for bio-imaging and efficient NIR/H2O2-responsive photodynamic therapy against hypoxic tumor cells. The nanoporous MOF shell can prevent aggregation of photosensitizers and serve as an efficient self-sufficient oxygen gas acceptor.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Luminescence Properties of Advanced Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
State Key Laboratory of Applied Organic Chemistry
Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province
College of Chemistry and Chemical Engineering
Lanzhou University
Lanzhou 730000
Department of Chemistry
University of Nebraska-Lincoln
Lincoln
USA
Funding
National Natural Science Foundation of China
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