journal article·2022-12-05Open access

Laser Therapy in Perianal Fistulas

Mircea Sandor, Maur Sebastian Horgos, Ioan Lucian Borza, Rodica Negrean, Mihai Botea, Szuhai Erika Bimbo, Anca Huniadi, Liliana Sachelarie, Loredana Liliana Hurjui, Irina Mihaela Jemnoschi Hreniuc

Applied Sciences· Volume 12· Issue 23

Abstract

(1) Background: Perianal fistula represents a chronic local suppuration, and recurrent or incorrectly treated, this pathology has a negative effect on the life of patients. (2) Methods: A 12-month prospective study was conducted with a study group (patients at the second presentation) and a control group (patients at the first presentation). The BTL-6000 brand laser has 50 times the maximum power of conventional laser devices with an unmatched wavelength of 1064 nm and a tissue penetration power of up to 10 cm. It is highly effective in speeding up healing and pain management (3) Results: Transcutaneous high-intensity laser therapy of perianal fistulas proved effective with a promising positive impact on both symptomatology and local signs in the study group. As for the patients in the control group, 37 of them required a second hospitalization due to the recurrence of symptoms and to whom the same laser therapy was applied. (4) Conclusions: A beneficial and positive effect was observed in our study, mainly on the symptoms determined by the appearance of the perianal fistula, both in the short- and long-term. High-frequency laser therapy is of major importance, considering the lower costs compared to surgery as well as the discomfort created during local treatments.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Anorectal Disease Treatments and Outcomes · Colorectal and Anal Carcinomas · Diverticular Disease and Complications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania

Department of Morphological Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania

Department of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania

Department of Preclinical Disciplines, Faculty of Dental Medicine, Apollonia University, 700511 Iasi, Romania

Department of Medical Disciplines, Faculty of Medicine and Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

References (25)

Show source-provided references
1. The Multidisciplinary Management of Perianal Fistulas in Crohn’s Disease: A Systematic Review
2. Perianal abscess10.1136/bmj.j475 ↗
3. Jimenez, M., and Mandava, N. (2022). Anorectal Fistula, StatPearls Publishing.
4. Carr, S., and Velasco, A.L. (2022). Fistula in Ano, StatPearls Publishing.
5. Management of Complex Perineal Fistula Disease10.1055/s-0036-1580631 ↗
6. Perianale Fistel und Analfissur10.1007/s00104-012-2297-7 ↗
7. Perianal abscess/fistula disease10.1055/s-2007-977488 ↗
8. Fistula treatment: The unresolved challenge10.1159/000320416 ↗
9. Incision and drainage of perianal abscess with or without treatment of anal fistula
10. Management of perianal fistula in inflammatory bowel disease: Identification of prognostic factors associated with surgery10.1007/s00423-021-02100-4 ↗
11. Review Article: Investigation and Management of Internal Fistulae in Crohn’s Disease10.1111/apt.16326 ↗
12. Guidelines for the Multidisciplinary Management of Crohn’s Perianal Fistulas: Summary Statement10.1097/MIB.0000000000000315 ↗
13. Burden of Disease and Adaptation to Life in Patients with Crohn’s Perianal Fistula: A Qualitative Exploration10.1186/s12955-020-01622-7 ↗
14. Comparative Efficacy and Safety of Biologic Therapies for Moderate-to-Severe Crohn’s Disease: A Systematic Review and Network Meta-Analysis10.1016/S2468-1253(21)00312-5 ↗
15. Outcomes of Perianal Fistulising Crohn’s Disease Following Anti-TNFα Treatment Discontinuation10.1093/ibd/izy008 ↗
16. Antibiotics and Azathioprine for the Treatment of Perianal Fistulas in Crohn’s Disease: Treatment for Perianal crohn’s Disease10.1046/j.1365-2036.2003.01793.x ↗
17. Perianal fistulizing Crohn’s disease: Pathogenesis, diagnosis and therapy10.1038/nrgastro.2017.104 ↗
18. Anoperineal Lesions in Crohn’s Disease: French Recommendations for Clinical Practice10.1007/s10151-017-1684-y ↗
19. A Meta-Analysis of Percutaneous Drainage Versus Surgery as the Initial Treatment of Crohn’s Disease-Related Intra-Abdominal Abscess10.1093/ecco-jcc/jjv198 ↗
20. An Overview of the Role of Exclusive Enteral Nutrition for Complicated Crohn’s Disease10.5217/ir.2018.00079 ↗
21. Modern management of perianal fistulas in Crohn’s disease: Future directions10.1136/gutjnl-2017-314918 ↗
22. ECCO Guidelines on Therapeutics in Crohn’s Disease: Surgical Treatment10.1093/ecco-jcc/jjz187 ↗
23. Treatment of peri-anal fistula in Crohn’s disease10.3748/wjg.v20.i37.13205 ↗
24. 3rd European Evidence-Based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 1: Diagnosis and Medical Management10.1093/ecco-jcc/jjw168 ↗
25. Clinical Practice Guideline for the Medical Management of Perianal Fistulizing Crohn’s Disease: The Toronto Consensus10.1093/ibd/izy247 ↗