journal article·2005-05

Magnetic fluid thermochemotherapy of murine tumors

Nikolai A. Brusentsov, Tatiana N. Brusentsova, Elena Yu. Filinova, Vycheslav D. Kuznetsov, Leonid I. Shumakov, Nikolai Y. Jurchenko

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Abstract

Abstract Four series of water-based dextran-ferrite (DF) magnetic fluids (MFs) containing Melphalan (MP) were prepared. Their saturation magnetization ( M s ) was from 0.8 to 7.8 kA/m; specific power absorption rates were 240 W/g Fe. After nine courses of magnetic fluid thermochemotherapy with MP containing DF MF ( M s 7.5 kA/m, pH 6.6, ζ+15 mV) at 44–46 °C for 30 min in an AC magnetic field (0.88 MHz, 9.3 kA/m, 0.3 kW), complete P388 tumor regression was seen in 30% of BDF 1 mice. Furthermore, a life span increase of 180% was achieved.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Nanoparticle-Based Drug Delivery · Characterization and Applications of Magnetic Nanoparticles · Cancer, Hypoxia, and Metabolism

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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