Investigation of the spontaneous transferability of a phospholipid-poly(ethylene glycol)-biotin derivative from small unilamellar phospholipid vesicles to magnetoliposomes
Source abstract
Abstract
Abstract High-gradient magnetophoresis was used to monitor the spontaneous transfer between phospholipid vesicles and magnetoliposomes of dipentadecanoylphosphatidylethanolamine (DC 15 PE) and of its conjugate with a biotinylated PEG molecule (DC 15 -PEG-B). For the latter molecule, a half-time of 70 min was found, whereas DC 15 PE did not move. The observed transferability of PEGylated phospholipids offers a unique method for generating Stealth ® -magnetoliposomes.
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Research context
OpenAlex topics: Lipid Membrane Structure and Behavior · Nanopore and Nanochannel Transport Studies · Force Microscopy Techniques and Applications
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References (20)
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