AC magnetic susceptibility and heat dissipation of Zn-doped Mg-ferrite nanoparticles
Source abstract
Abstract
Mg 1- xZn xFe 2O 4 ( x = 0.0, 0.2, 0.4, 0.6, 0.8) nanoparticles surrounded by amorphous SiO 2 were synthesized using the wet chemical method to improve their biocompatibility and magnetization, and for application as a heating medium for hyperthermia therapy. Magnetization was at its maximum for a composition of x = 0.2; this composition was then fixed and the particle size varied between 4 and 25 nm to optimize the heating effect. Analysis by alternating-current (AC) magnetic-susceptibility measurement suggested that particles sized 18 nm generated the most heat, with the system following a Debye relaxation. In the temperature-increase measurement, the maximum amount of heat was dissipated at a particle size of 18 nm, indicating that the system generates enough heat to kill cancer cells under electromagnetic fields that are acceptable to the human body. In an in vitro experiment using human breast cancer cells, we confirmed that hyperthermia suppressed 25% of the cancer cells in 30 min using 18 nm particles.
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Research context
OpenAlex topics: Characterization and Applications of Magnetic Nanoparticles · Magnetic Properties and Synthesis of Ferrites · Nanoparticle-Based Drug Delivery
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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