journal article·2020-01

A physical model for the characterization of magnetic hydrogels subject to external magnetic fields

Dario Madeo, Giuseppe Bevilacqua, Valerio Biancalana, Yordanka Dancheva, Chiara Mocenni

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Abstract

Abstract Magnetic hydrogels are interesting nanomaterials able to change their shape and temperature if exposed to external magnetic fields. Thanks to these features, which originate from the microstructure of magnetic hydrogels (magnetic nanoparticles tied together through polymeric chains), these substances have several applications in technological fields and biomedicine. Hydrogels are able to absorb and release large amounts of water, which makes them eligible materials for drug delivery. This feature is made even more attractive in cases where the delivery/release can be externally controlled. Controlling the system using external magnetic fields requires keystone processes like modeling and simulation. In this paper, the properties of the system have been analyzed using a 2D microscopical simulation of a suitable physical model. Experimentally, the behavior of the system with and without the application of external magnetic fields and its dissipative effects have been characterized. Specifically, we analyze the change of size and temperature of an hydrogel system as a function of the external magnetic field frequency, thus providing a fundamental tool for developing magnetic substances suitable for specific applications.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Characterization and Applications of Magnetic Nanoparticles · Micro and Nano Robotics · Hydrogels: synthesis, properties, applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (68)

Show source-provided references
1. Magnetic nanoparticles
2. Functionalised magnetic nanoparticles for uranium adsorption with ultra-high capacity and selectivity10.1039/C7TA09240G ↗
3. Spectrally coded optical data storage by metal nanoparticles10.1364/OL.25.000563 ↗
4. The emergence of spin electronics in data storage
5. Magnetic nanoparticle-based gyroscopic sensor: a review10.1109/JSEN.2015.2427375 ↗
6. Gyroscopic behavior exhibited by the optical kerr effect in bimetallic Au–Pt nanoparticles suspended in ethanol10.1007/s11051-016-3510-2 ↗
7. Magnetoelastic sensor for magnetic nanoparticle detection10.1016/j.jmmm.2018.05.108 ↗
8. Nanoparticles: health effects – pros and cons10.1289/ehp.8871 ↗
9. Nanotechnology and health safety–toxicity and risk assessments of nanostructured materials on human health10.1166/jnn.2007.922 ↗
10. Applications of magnetic nanoparticles in biomedicine10.1088/0022-3727/36/13/201 ↗
11. Medical application of functionalized magnetic nanoparticles10.1263/jbb.100.1 ↗
12. Progress in applications of magnetic nanoparticles in biomedicine10.1088/0022-3727/42/22/224001 ↗
13. The role of cobalt ferrite magnetic nanoparticles in medical science10.1016/j.msec.2012.09.003 ↗
14. Magnetic fluid hyperthermia (MFH): cancer treatment with ac magnetic field induced excitation of biocompatible superparamagnetic nanoparticles10.1016/S0304-8853(99)00088-8 ↗
15. Folate-conjugated iron oxide nanoparticles for solid tumor targeting as potential specific magnetic hyperthermia mediators: synthesis, physicochemical characterization, and in vitro experiments10.1021/bc050050z ↗
16. Thermoresponsive magnetic composite nanomaterials for multimodal cancer therapy10.1016/j.actbio.2009.07.004 ↗
17. Platinum nanoparticles: a non-toxic, effective and thermally stable alternative plasmonic material for cancer therapy and bioengineering10.1039/C8NR02275E ↗
18. Effect of magnetic nanoparticles coating on cell proliferation and uptake10.1016/j.jmmm.2018.09.116 ↗
19. Positive contrast magnetic resonance imaging of cells labeled with magnetic nanoparticles10.1002/mrm.20477 ↗
20. Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging10.1038/nm1467 ↗
21. Multifunctional magnetic nanoparticles for medical imaging applications10.1039/b902182e ↗
22. Magnetophoretic induced convective capture of highly diffusive superparamagnetic nanoparticles10.1039/C7SM02324C ↗
23. Nanoparticles: a challenging vehicle for neural stimulation10.3389/fnins.2016.00105 ↗
24. Nanomaterial-enabled neural stimulation10.3389/fnins.2016.00069 ↗
25. Stimuli-responsive hydrogels cross-linked by magnetic nanoparticles10.1039/c3sm27809c ↗
26. Deformation mechanisms in 2d magnetic gels studied by computer simulations10.1039/c2sm26097b ↗
27. Towards a scale-bridging description of ferrogels and magnetic elastomers
28. Shear modulus of isotropic ferrogels10.1016/j.jmmm.2019.01.015 ↗
29. Heating efficiency of magnetic nanoparticles decreases with gradual immobilization in hydrogels10.1016/j.jmmm.2018.09.113 ↗
30. Magnetic nanoparticles and targeted drug delivering10.1016/j.phrs.2010.01.014 ↗
31. Magnetic nanoparticles in MR imaging and drug delivery10.1016/j.addr.2008.03.018 ↗
32. Controlled pulsatile drug release from a ferrogel by a high-frequency magnetic field10.1021/ma0707584 ↗
33. Design of hybrid nanovehicles for remotely triggered drug release: an overview10.1039/C5TB00664C ↗
34. Crosslinking metal nanoparticles into the polymer backbone of hydrogels enables preparation of soft, magnetic field-driven actuators with muscle-like flexibility10.1002/smll.200801091 ↗
35. Design parameters for magneto-elastic soft actuators10.1088/0964-1726/19/5/055017 ↗
36. Rafii-Tabar · 2008
37. Modeling of the mechanical properties of nanoparticle/polymer composites10.1016/j.polymer.2004.11.022 ↗
38. Continuum models of stimuli-responsive gels
39. Mechanical properties of magneto-sensitive elastomers: unification of the continuum-mechanics and microscopic theoretical approaches10.1039/C3SM52440J ↗
40. Nonlocal continuum-based modeling of mechanical characteristics of nanoscopic structures10.1016/j.physrep.2016.05.003 ↗
41. Design of nanoparticle-based carriers for targeted drug delivery10.1155/2016/1087250 ↗
42. Continuum-based models and concepts for the transport of nanoparticles in saturated porous media: a state-of-the-science review10.1016/j.cis.2017.06.002 ↗
43. Development of a continuum model for ferrogels10.1177/1045389X16672564 ↗
44. Modeling and finite element simulation of the magneto-mechanical behavior of ferrogels10.1016/j.jmmm.2016.09.058 ↗
45. The magneto-mechanical behavior of active components in iron-elastomer composite10.3390/jcs2030054 ↗
46. Modelling of iron-filled magneto-active polymers with a dispersed chain-like microstructure10.1016/j.euromechsol.2014.10.005 ↗
47. Finite element simulation of rate-dependent magneto-active polymer response10.1088/0964-1726/25/10/104003 ↗
48. Theoretical models for magneto-sensitive elastomers: a comparison between continuum and dipole approaches10.1103/PhysRevE.95.042501 ↗
49. Ferrogels cross-linked by magnetic particles: field-driven deformation and elasticity studied using computer simulations10.1063/1.4932371 ↗
50. Designing hysteresis with dipolar chains10.1103/PhysRevLett.120.157202 ↗
51. Large scale finite-element simulation of micromagnetic thermal noise10.1016/j.jmmm.2018.11.106 ↗
52. GROMACS 4: algorithms for highly efficient, load-balanced, and scalable molecular simulation10.1021/ct700301q ↗
53. Espresso 3.1: molecular dynamics software for coarse-grained models
54. Vegas: software package for the atomistic simulation of magnetic materials10.31349/RevMexFis.64.490 ↗
55. Dissipative particle dynamics: bridging the gap between atomistic and mesoscopic simulation10.1063/1.474784 ↗
56. Allen · 2017
57. A simple algorithm to accelerate the computation of non-bonded interactions in cell-based molecular dynamics simulations10.1002/jcc.20563 ↗
58. Role of repulsive forces in determining the equilibrium structure of simple liquids10.1063/1.1674820 ↗
59. Molecular dynamics simulations of auxetic ferrogel
60. Molecular dynamics study on the equilibrium magnetization properties and structure of ferrofluids10.1103/PhysRevE.66.021405 ↗
61. Efficient algorithms for langevin and dpd dynamics10.1021/ct3000876 ↗
62. Fluctuation–dissipation: response theory in statistical physics10.1016/j.physrep.2008.02.002 ↗
63. Rapaport · 2004
64. Velocity Verlet algorithm for dissipative-particle-dynamics-based models of suspensions10.1103/PhysRevE.59.3733 ↗
65. Robust rotational-velocity-Verlet integration methods10.1103/PhysRevE.81.056706 ↗
66. How would you integrate the equations of motion in dissipative particle dynamics simulations?10.1016/S0010-4655(03)00202-9 ↗
67. System Identification: Theory for the User
68. Grosso · 2000