journal article·2025-04

Gold nanocage-carbon nanodot composites activate ornidazole against biofilm infections through modulating the hypoxic microenvironment

Zekun Wang, Yingying Li, Hanqing Zhao, Fangyuan Chen, Wenjun Shao, Man Jiang, Lu Zhang, Tao Ma, Qingqing Wang

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OpenAlex topics: Nanoplatforms for cancer theranostics · Luminescence and Fluorescent Materials · Advanced Nanomaterials in Catalysis

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References (46)

Show source-provided references
1. Microalgae-based bioactive hydrogel loaded with quorum sensing inhibitor promotes infected wound healing10.1016/j.nantod.2021.101368 ↗
2. Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections10.1038/s41579-020-0420-1 ↗
3. Strategies to promote the journey of nanoparticles against biofilm-associated infections10.1002/smll.202305988 ↗
4. H2O2 self-supplying and GSH-depleting nanosystem for amplified NIR mediated-chemodynamic therapy of MRSA biofilm-associated infections10.1186/s12951-024-02350-6 ↗
5. Strategy for treatment of infected diabetic foot ulcers10.1021/acs.accounts.0c00864 ↗
6. Antibiotic-derived carbon-nanodot-decorated hydrogel for reactive oxygen species-enhanced anti-infection through biofilm damage10.1002/adfm.202300341 ↗
7. Copper ion-inspired dual controllable drug release hydrogels for wound management: driven by hydrogen bonds
8. Enhanced antibiofilm photodynamic therapy: leveraging the slow photon effect for maximized efficacy with minimal photosensitizer and light doses10.1016/j.nantod.2024.102225 ↗
9. Phase separation of extracellular polymeric substances induced by bacteria responsive Nano-antibiotics for drug-resistant bacterial infection management10.1016/j.cej.2023.148136 ↗
10. Promoting the healing of infected diabetic wound by an anti-bacterial and nano-enzyme-containing hydrogel with inflammation-suppressing, ROS-scavenging, oxygen and nitric oxide-generating properties10.1016/j.biomaterials.2022.121597 ↗
11. Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy10.1038/s41467-023-43067-8 ↗
12. Infection microenvironment-triggered nanoparticles eradicate MRSA by thermally amplified chemodynamic therapy and M1 macrophage10.1186/s12951-024-02706-y ↗
13. Targeting microbial biofilms: current and prospective therapeutic strategies10.1038/nrmicro.2017.99 ↗
14. The biofilm life cycle: expanding the conceptual model of biofilm formation10.1038/s41579-022-00767-0 ↗
15. Injectable self-expanding/self-propelling hydrogel adhesive with procoagulant activity and rapid gelation for lethal massive hemorrhage management
16. Methicillin-resistant Staphylococcus aureus10.1038/nrdp.2018.33 ↗
17. Surface chemistry engineered selenium nanoparticles as bactericidal and immuno-modulating dual-functional agents for combating methicillin-resistant Staphylococcus aureus infection, Drug Resist
18. An injectable multifunctional hydrogel for eradication of bacterial biofilms and wound healing10.1016/j.actbio.2023.03.008 ↗
19. Potentiating hypoxic microenvironment for antibiotic activation by photodynamic therapy to combat bacterial biofilm infections10.1038/s41467-022-31479-x ↗
20. Biofilm-specific antibiotic tolerance and resistance10.1007/s10096-015-2323-z ↗
21. A pH-responsive hydrogel with potent antibacterial activity against both aerobic and anaerobic pathogens10.1039/C8BM01211C ↗
22. Ornidazole-loaded graphene paper for combined antibacterial materials10.1016/j.jscs.2017.10.002 ↗
23. Synthesis and therapeutic potential of imidazole containing compounds10.1186/s13065-020-00730-1 ↗
24. Multiparticulate based thermosensitive intra-pocket forming implants for better treatment of bacterial infections in periodontitis10.1016/j.ijbiomac.2018.04.179 ↗
25. PTT/PDT-induced microbial apoptosis and wound healing depend on immune activation and macrophage phenotype transformation10.1016/j.actbio.2023.06.025 ↗
26. Interfacial regulation of BiOI@Bi2S3/MXene heterostructures for enhanced photothermal and photodynamic therapy in antibacterial applications10.1016/j.actbio.2023.09.036 ↗
27. l-arg-rich amphiphilic dendritic peptide as a versatile NO donor for NO/photodynamic synergistic treatment of bacterial infections and promoting wound healing10.1002/smll.202101495 ↗
28. Enhancing near-infrared II photodynamic therapy with nitric oxide for eradicating multidrug-resistant biofilms in deep tissues
29. Multifunctional photoactive hydrogels for wound healing acceleration10.1021/acsnano.1c08334 ↗
30. NIR II-triggered core-shell upconversion nanocomposites for peroxynitrite-boosted anti-infection against diabetic wound10.1016/j.cej.2023.148271 ↗
31. Biofilm microenvironment response nanoplatform synergistically degrades biofilm structure and relieves hypoxia for efficient sonodynamic therapy10.1016/j.cej.2022.139839 ↗
32. Enzyme-like photocatalytic octahedral Rh/Ag2MoO4 accelerates diabetic wound healing by photo-eradication of pathogen and relieving wound hypoxia10.1002/smll.202402723 ↗
33. l-arginine-loaded gold nanocages ameliorate myocardial ischemia/reperfusion injury by promoting nitric oxide production and maintaining mitochondrial function10.1002/advs.202302123 ↗
34. Recent progress of antibacterial hydrogels in wound dressings
35. Cascade-targeting poly(amino acid) nanoparticles eliminate intracellular bacteria via on-site antibiotic delivery10.1002/adma.202109789 ↗
36. Sustained reduction of antibiotic use and low bacterial resistance:: 10-year follow-up of the Swedish Strama programme10.1016/S1473-3099(08)70017-3 ↗
37. Co-delivery of ampicillin and fl-lactamase inhibitor by selenium nanocomposite to achieve synergistic anti-infective efficiency through overcoming multidrug resistance10.1016/j.cej.2021.128908 ↗
38. Synthesis of carbon dots with multiple color emission by controlled graphitization and surface functionalization
39. Red-emissive carbon dots for fluorescent, photoacoustic, and thermal theranostics in living mice10.1002/adma.201500323 ↗
40. Antibacterial gas therapy: strategies, advances, and prospects
41. Antimicrobial hybrid amphiphile via dynamic covalent bonds enables bacterial biofilm dispersal and bacteria eradication10.1002/adfm.202214299 ↗
42. Antibacterial microneedle patch releases oxygen to enhance diabetic wound healing
43. Biofilm microenvironment-responsive nanoparticles for the treatment of bacterial infection10.1016/j.nantod.2022.101602 ↗
44. Flexible nanoplatform facilitates antibacterial phototherapy by simultaneously enhancing photosensitizer permeation and relieving hypoxia in bacterial biofilms10.1016/j.actbio.2024.06.018 ↗
45. pH-switchable antimicrobial nanofiber networks of Hydrogel eradicate biofilm and rescue stalled healing in chronic wounds10.1021/acsnano.9b05608 ↗
46. Immunology of acute and chronic wound healing10.3390/biom11050700 ↗