journal article·1994-09-01

Free electron laser irradiation at 200 μm inhibits DNA synthesis in living cells

Michael W. Berns, William Bewley, Chung-Ho Sun, Pamela Templin, Alexander Karn

Journal of Laser Applications· Volume 6· Issue 3
Publisher page

Abstract

The effect of a 200 μm wavelength free electron laser (FEL) beam on vertebrate tissue culture cells in two study series is described. Cell cultures exhibited no morphological alterations. However, a statistically significant proportion of the cells exhibited a reduction in tritiated thymidine incorporation. The results suggest that this wavelength might affect DNA synthesis, and the studies demonstrate the feasibility of biological investigations with the FEL.
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Research context

OpenAlex topics: Laser Applications in Dentistry and Medicine · Laser Material Processing Techniques · Laser Design and Applications

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Affiliations

1Beckman Laser Institute and Medical Clinic, University of California at Irvine, 1002 Health Sciences Road East, Irvine, CA 92715, U.S.A.

2Department of Physics, University of California at Santa Barbara, Santa Barbara CA 93106, U.S.A.

References

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